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Skip search results from other journals and go to results- 4 JMIR Public Health and Surveillance
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Laboratory testing plays a key role in clinical decision-making and physician orders for laboratory tests are increasing [1,2]. It is estimated that at least 20% of the 4-5 billion lab orders submitted annually in the United States are inappropriate. Studies have shown that overutilization and underutilization of laboratory tests occur 20.6% and 44.8% of the time, respectively [3].
Interact J Med Res 2025;14:e46007
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Hepatitis refers to inflammation of the liver and is characterized by an increase in transaminase levels, for which quantitative recordings are available in clinical laboratory databases [9,10]. These routinely collected laboratory data are rarely exploited for public health surveillance, but could be used as an opportunistic measure for disease surveillance in new or periodic outbreaks.
JMIR Public Health Surveill 2024;10:e55376
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The test center in Denmark’s PCR laboratory at Statens Serum Institut, which performs the PCR analyses for this study, is ISO/IEC 17025 accredited.
The participants enrolled in the study will receive an online questionnaire 3 months after enrollment to follow up on the number and length of symptoms after they were tested (see Multimedia Appendix 1).
This trial was reported to the Regional Ethics Committee of the Capital Region of Denmark which considered it exempted from further processing (H-22022937).
JMIR Res Protoc 2024;13:e47446
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Health care providers depend on laboratory results to decide on differentiated care models and tuberculosis screening [6]. For a national HIV program to be highly successful and reduce HIV-related deaths, the health system must integrate data from an effective clinical laboratory system. Access to quality laboratory services remains a challenge in low- and middle-income countries (LMICs), and many still rely on paper-based records [7].
JMIR Public Health Surveill 2024;10:e50407
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The data source contained comprehensive inpatient and outpatient claims records, laboratory test results, and individual and various aggregated demographic information. In this study, we leveraged the outpatient laboratory data set for SARS-Co V-2 to assemble the cohort.
The Harvard Medical School Institutional Review Board waived the approval requirement for this study as our database analysis is not regarded as human participants research (IRB20-0935).
J Med Internet Res 2024;26:e44249
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Samples can be sent to a laboratory for culture-based testing; tested using a rapid antigen detection test, which has a sensitivity of 70%-90% for GABHS [2] and can provide a result in a few minutes; or could potentially be used for novel tests involving molecular techniques [10] and testing for evidence of host response. However, throat swabbing has traditionally only been available as part of a face-to-face consultation, and it is unclear whether patients or parents are able to self-sample at home.
J Med Internet Res 2023;25:e39791
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Challenges to global control of SARS-Co V-2 have underscored the need for accurate, safe, and rapidly scalable laboratory testing to inform rapid diagnosis and implementation of appropriate clinical and public health measures. Furthermore, early detection of emerging infectious disease threats is critical to limit spread. Over the last 4 decades, 1-3 newly emerging pathogens have been identified annually [1].
JMIR Form Res 2023;7:e32848
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Therefore, every laboratory should establish RIs suitable for its specific service populations.
Previous studies have demonstrated that RIs can be established through direct, indirect, and transference methods [2], each of which has particular applicable conditions and relative advantages. Generally, the Clinical and Laboratory Standards Institute (CLSI) endorses direct methods over the other 2 types of methods [2].
J Med Internet Res 2023;25:e45651
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A Wolf in Sheep’s Clothing: Reuse of Routinely Obtained Laboratory Data in Research
In 2005, the Central Diagnostic Laboratory of the University Medical Center Utrecht (UMCU) began collecting EHRs, including raw data from our International Organization for Standardization (ISO)-15189 certified laboratory, and compiling them in the Utrecht Patient Orientated Database (UPOD) [4].
J Med Internet Res 2022;24(11):e40516
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Drill-Hole Bone Defects in Animal Models of Bone Healing: Protocol for a Systematic Review
This systematic review aims to provide a detailed description of the different methods used to induce drill-hole bone defects in long bones of laboratory animals and to provide a comprehensive overview of their methodology and potential for investigation of bone healing. This research question has been formulated following the Population, Intervention, Comparison, and Outcome (PICO) framework [29].
This review will include all in vivo animal studies using drill-hole bone defects.
JMIR Res Protoc 2022;11(7):e34887
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