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Modernizing the Staging of Parkinson Disease Using Digital Health Technology
J Med Internet Res 2025;27:e63105
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The reported P value is defined as the proportion of permutations that resulted in a mean difference between the 2 permuted groups that is larger than the real observed mean difference between the subgroup and its reference group. Both unadjusted and adjusted P values (adjusted for multiple comparisons with false discovery rate correction using the Benjamini-Hochberg method) are reported.
J Med Internet Res 2025;27:e63090
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Statistical significance was defined as P
Of the 3684 participants screened for eligibility, 633 participants were excluded (346 declined participation and 287 did not meet eligibility criteria; Figure 2). The program started with 3051 participants, of which 2367 participants completed it, translating into a completion rate of 77.6%.
Study flowchart.
JMIR Mhealth Uhealth 2025;13:e68242
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P values for the chi-square test are given.
a EV: embryonic volume.
b Not applicable.
c GA: gestational age.
d HV: head volume.
For the HV, a total of 475 ultrasound scans of 326 participants were included. The data were divided over similar subsets. The development set contained 383 ultrasound scans of 261 participants acquired before 2020. The test set contained 92 ultrasound scans of 65 participants acquired before 2020. The future test set contained 80 ultrasound scans of 58 participants acquired in 2020.
J Med Internet Res 2025;27:e60887
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P
A total of 20 participants participated in the course to which they were assigned and the first simulation-based assessment. Of these, 16 (80%) participants, with 8 (40%) in each group, participated in the second simulation-based assessment at 6 months. However, 1 (5%) participant in the control group did not complete the assessment, and data from this participant were not included in the grouped responses for the second assessment (Figure 3).
JMIR Form Res 2025;9:e58542
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The scoping review protocol has been registered on the Open Science Framework Registries [30] and was guided by and reported according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) [31]. The completed PRISMA-P checklist can be found in Multimedia Appendix 1. The results of the scoping review will be reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-Sc R) checklist [32].
JMIR Res Protoc 2025;14:e65733
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