This paper is in the following e-collection/theme issue:

Health Services in Resource-Poor Settings and LMICs (413) Perinatal Education for Parents (219) Midwifery, Nurse-midwifery and Care for Pregnant or New Mothers (59)

Published on in Vol 10 (2024)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/49367, first published .
Spatial Access to Continuous Maternal and Perinatal Health Care Services in Low-Resource Settings: Cross-Sectional Study

Spatial Access to Continuous Maternal and Perinatal Health Care Services in Low-Resource Settings: Cross-Sectional Study

Spatial Access to Continuous Maternal and Perinatal Health Care Services in Low-Resource Settings: Cross-Sectional Study

Authors of this article:

Qin Li1, 2 Author Orcid Image ;   Elsa Kanduma3 Author Orcid Image ;   Isaías Ramiro3 Author Orcid Image ;   Dong (Roman) Xu4, 5 Author Orcid Image ;   Rosa Marlene Manjate Cuco6 Author Orcid Image ;   Eusebio Chaquisse6 Author Orcid Image ;   Yili Yang1, 2 Author Orcid Image ;   Xiuli Wang1, 2 Author Orcid Image ;   Jay Pan1, 7 Author Orcid Image
Article Authors Cited by (1) Tweetations (1) Metrics

    Original Paper

    1HEOA Group, West China School of Public Health, West China Fourth Hospital, Sichuan University, Chengdu, China

    2Institute for Healthy Cities, West China Research Center for Rural Health Development, Sichuan University, Chengdu, China

    3Comité para a Saúde de Moçambique, Maputo City, Mozambique

    4Acacia Lab for Implementation Science, Center for World Health Organization Studies, School of Health Management, Southern Medical University, Guangzhou, China

    5SMU Institute for Global Health, Dermatology Hospital, Southern Medical University, Guangzhou, China

    6Mozambique Ministry of Health and Faculty of Medicine, Eduardo Mondlane University, Maputo City, Mozambique

    7China Center for South Asian Studies, Sichuan University, Chengdu, China

    *these authors contributed equally

    Corresponding Author:

    Jay Pan, PhD

    HEOA Group

    West China School of Public Health, West China Fourth Hospital

    Sichuan University

    17 People’s South Road

    Chengdu, 610041

    China

    Phone: 86 1 861 579 9937

    Email: panjie.jay@scu.edu.cn


    Background: Maternal and perinatal health are fundamental to human development. However, in low-resource settings such as sub-Saharan Africa (SSA), significant challenges persist in reducing maternal, newborn, and child mortality. To achieve the targets of the sustainable development goal 3 (SDG3) and universal health coverage (UHC), improving access to continuous maternal and perinatal health care services (CMPHS) has been addressed as a critical strategy.

    Objective: This study aims to provide a widely applicable procedure to illuminate the current challenges in ensuring access to CMPHS for women of reproductive age. The findings are intended to inform targeted recommendations for prioritizing resource allocation and policy making in low-resource settings.

    Methods: In accordance with the World Health Organization guidelines and existing literature, and taking into account the local context of CMPHS delivery to women of reproductive age in Mozambique, we first proposed the identification of CMPHS as the continuum of 3 independent service packages, namely antenatal care (ANC), institutional delivery (ID), and postnatal care (PNC). Then, we used the nearest-neighbor method (NNM) to assess spatial access to each of the 3 service packages. Lastly, we carried out an overlap analysis to identify 8 types of resource-shortage zones.

    Results: The median shortest travel times for women of reproductive age to access ANC, ID, and PNC were 2.38 (IQR 1.38-3.89) hours, 3.69 (IQR 1.87-5.82) hours, and 4.16 (IQR 2.48-6.67) hours, respectively. Spatial barriers for women of reproductive age accessing ANC, ID, and PNC demonstrated large variations both among and within regions. Maputo City showed the shortest travel time and the best equity within the regions (0.46, IQR 0.26-0.69 hours; 0.74, IQR 0.47-1.04 hours; and 1.34, IQR 0.83-1.85 hours, respectively), while the provinces of Niassa (4.07, IQR 2.41-6.63 hours; 18.20, IQR 11.67-24.65 hours; and 7.69, IQR 4.74-13.05 hours, respectively) and Inhambane (2.69, IQR 1.49-3.91 hours; 4.43, IQR 2.37-7.16 hours; and 10.76, IQR 7.73-13.66 hours, respectively) lagged behind significantly in both aspects. In general, more than 51% of the women of reproductive age, residing in 83.25% of Mozambique’s land area, were unable to access any service package of CMPHS in time (within 2 hours), while only about 21%, living in 2.69% of Mozambique’s land area, including Maputo, could access timely CMPHS.

    Conclusions: The spatial accessibility and equity of CMPHS in Mozambique present significant challenges in achieving SDG3 and UHC, especially in the Inhambane and Niassa regions. For Inhambane, policy makers should prioritize the implementation of a decentralization allocation strategy to increase coverage and equity through upgrading existing health care facilities. For Niassa, the cultivation of well-trained midwives who can provide door-to-door ANC and PNC at home should be prioritized, with an emphasis on strengthening communities’ engagement. The proposed 2-step procedure should be implemented in other low-resource settings to promote the achievement of SDG3.

    JMIR Public Health Surveill 2024;10:e49367

    doi:10.2196/49367

    Keywords

    continuous maternal and perinatal health care services; sub-Saharan Africa; SSA; spatial access; resource allocation; low-resource settings 


    Access to continuous maternal and perinatal health care services (CMPHS) has been proposed by the World Health Organization (WHO) as an essential strategy to improve maternal and child health [1]. Instead of focusing on single interventions, CMPHS emphasizes packages of interventions delivered throughout the lifecycle at all levels of health care facilities in the health delivery system [2]. The provision of CMPHS is also a priority for achieving universal health coverage (UHC) and is listed as a key indicator for monitoring the progress of maternal, newborn, and child outcomes [3]. It has been widely recognized that CMPHS can be understood as the integration of 3 service delivery packages: antenatal care (ANC), institutional delivery (ID), and postnatal care (PNC) [4]. ANC facilitates the prompt detection and management of complications among pregnant women [5]. Research suggests that even a 7% increase in ANC coverage might save 160,000 newborn lives annually in Africa [6]. ID ensures appropriate equipment and supplies are available on site or through immediate referral to a higher-level facility if necessary [7]. As suggested by the literature, perinatal mortality is 21% lower for facility-based deliveries compared to home deliveries. In the best settings, up to 14 perinatal deaths might be averted per 1000 births if the obstetric deliveries occurred at facilities instead of at homes [8]. PNC provides great opportunities to check for dangerous signs and symptoms associated with poor health outcomes in babies [9]. The importance of PNC has been documented, with an estimation that if PNC rates reach 90% in sub-Saharan Africa (SSA), neonatal deaths could be averted by 10%-27% [10].

    Mozambique represents a low-resource setting of the type prevalent in the SSA region, where the world’s highest maternal and neonatal mortality persists as a critical issue (533 maternal deaths per 100,000 live births vs 211 per 100,000 worldwide and 27 neonatal deaths per 1000 live births vs 18 per 1000 worldwide). Timely provision of CMPHS could prevent a significant proportion of these deaths [11-13]. Several recent studies have examined health care accessibility in low-resource settings, including emergency obstetric and newborn care, skilled birth attendance and caesarean delivery services, and primary health care [14-18]. However, efforts to assess the spatial accessibility of CMPHS remain insufficient [19] despite widespread recognition that the effectiveness of the 3 service packages is greatly influenced by health care services achieved in the previous stages. Moreover, there is a lack of targeted suggestions on resource investment and policy making in this area.

    Among various barriers preventing women of reproductive age from obtaining timely access to CMPHS, spatial accessibility (geographic proximity) has become one of the primary barriers, particularly in low-resource settings [20]. As a crucial aspect of accessibility, use, and the provision of health care services to the population group in need [21], assessment of spatial accessibility has been carried out worldwide and been incorporated into policy making in many countries. However, there is a paucity of studies assessing the spatial accessibility of CMPHS by integrating multiple indicators into 3 separate service packages in low-resource settings.

    As the deadline for sustainable development goal 3 (SDG3) approaches, and the fundamental need for maternal and prenatal health care persists, the efficient allocation of limited health care resources, especially in low-resource settings, is of great importance. Mozambique, one of the world’s poorest and most underdeveloped countries (with a United Nations Human Development Index of 0.446 in 2021), faces significant challenges in implementing SDG3, particularly concerning CMPHS indicators [22]. This study uses Mozambique as a case study, aiming to provide a widely applicable procedure for assessing the spatial access to CMPHS and to offer evidence-based suggestions for policy makers that will guide the prioritization of health resource allocation to improve CMPHS accessibility and maternal, newborn, and child health outcomes in low-resource settings.


    Study Area

    Mozambique, located on the southeast coast of Africa, is divided into 11 provinces, including 1 provincial city (Multimedia Appendix 1, Figure S1A). According to data announced by the General Population and Housing Census 2017 in Mozambique [23], the estimated total population was 30.07 million, with the majority living in rural areas and generally sparsely and unevenly distributed (Multimedia Appendix 1, Figure S1B). Nearly 80% of people living in poverty live in rural areas distant from basic public facilities [24]. The country’s overall economy remains extremely underdeveloped (gross domestic product <US $1.00/person/day); the highest average consumption level in Maputo City is 6.9 times higher than the lowest, in Zambezia province (Multimedia Appendix 1, Figure S1C) [25].

    According to a report from the Mozambique Ministry of Health, the country’s maternal mortality rate was as high as 451 deaths per 100,000 live births, and the infant mortality rate was 67.4 deaths per 1000 live births in 2020 [26]. Factors such as long travel distances from residential locations to health care facilities, lack of available transportation, and poorly constructed transportation networks contribute to significant service delays for women of reproductive age accessing CMPHS [15,27].

    Data Sources

    Data on 2 perspectives were needed for identifying indicators reflective of the delivery of the 3 service packages in Mozambique for calculating spatial accessibility. Following the existing literature and considering both representativeness and implementability, 2 categories of data were used for indicator identification and 3 categories of data were used to facilitate the analysis of spatial accessibility, including supply side data (health care facility data), demand side data (distribution data for women of reproductive age), and environmental data (for calculating geospatial barriers) [28-30]. The data sources are shown in detail in Table 1.

    Table 1. Description and sources of data use in the 2 steps of the proposed procedure.
    PerspectivesData typeData descriptionData sources
    Identifying indicators representing 3 service packages of CMPHSa in MozambiqueFor representativeness: global guidelinesGuidelines for essential practice in maternal, newborn, and child health and pregnancy, childbirth, postpartum, and newborn careWorld Health Organization guidelines [31,32]
    For implementability: Mozambique-specific dataContinuous maternal and perinatal health care services (antenatal care, institutional delivery, and postnatal care)The questionnaire of the National Survey on Infrastructure, Equipment, Human Resources and Health Services 2018
    Calculating spatial accessibility of CMPHS in MozambiqueSupply side: health care facility dataGeographic coordinates (longitude, latitude) of all health care facilitiesPublic health facilities in sub-Saharan Africa; Figshare data set [33] and Google Maps
    Address of all health care facilitiesThe questionnaire of the National Survey on Infrastructure, Equipment, Human Resources and Health Services 2018
    Demand side: population dataData on number of women of reproductive age at the provincial level (2018)Statistical Yearbook 2018 of Mozambique [34]
    Raster data on spatial distribution of pregnancies at 1×1 km2 resolution (2015)WorldPop provides open geospatial data on distribution of pregnancies in Mozambique [35]
    Environmental dataAdministrative boundariesOpenStreetMap [36]

    aCMPHS: continuous maternal and perinatal health care services.

    Data Pretreatment and Analysis

    A detailed flowchart describing the 2-step procedure is shown in Figure 1.

    ‎
    Figure 1. Flowchart of the proposed 2-step procedure, including the main process and data used in each process. ANC: antenatal care; CMPHS: continuous maternal and perinatal health care services; ID: institutional delivery; MNCH: maternal, newborn, and child health; PCPNC: pregnancy, childbirth, postpartum and newborn care; PNC: postnatal care; WHO: World Health Organization.
    Step 1: Identification of Indicators Representing the 3 Service Packages of CMPHS

    The selection of indicators was based on 2 main principles. The first principle was accordance with maternal, newborn, and child health (MNCH) guidelines, as well as the pregnancy, childbirth, postpartum, and newborn care (PCPNC) guidelines proposed by the WHO. The second principle was to fully reflect the region-specific characteristics of CMPHS delivery in the study area.

    In adhering to the 2 main principles, recommended and available indicators were first filtered to identify a group of separate indicators from each individual service package. The available indicators were extracted from Mozambique’s Survey on Infrastructure, Equipment, Human Resources and Health Services 2018 (Multimedia Appendix 1, Table S1) [37,38]. Then, with consideration of both avoiding fragmented services and ensuring the quality of CMPHS, as well as extensive reference to existing literature, [39], the filtered indicators were further screened and integrated to the 3 service packages. ANC includes 7 integrated indicators, ID includes 8 integrated indicators, and PNC includes 10 integrated indicators (Multimedia Appendix 1, Table S2).

    Step 2: Calculation of Spatial Access to CMPHS (Data Pretreatment)

    For the supply side data, 3 levels of health care facilities were included, consisting of Mozambique’s health care delivery system: primary (urban and rural health centers and community health posts), secondary (rural, district, and general hospitals), and tertiary (central and provincial, specialized, and military hospitals). Combined with results from step 1, the capability of delivering the 3 service packages of CMPHS was identified for every health care facility.

    For demand side data, gridded estimates of pregnancies were obtained at 1×1 km2 spatial resolution from the WorldPop database for 2015, which served to weight the spatial distribution of the demand side data. Then, data on the nationally announced provincial-level aggregated number of women aged 15-49 years in Mozambique was used to adjust the spatial distribution of pregnant women at a resolution of 1×1 km2 to generate a more accurate and up-to-date demand distribution, as process generally used in related research [40-42].

    The following formula was used to calculate the spatial distribution of women of reproductive age at 1×1 km2 resolution [40], in which Pij is the number of women of reproductive age of grid i in the province or provincial capital j, and Gij is the corresponding WorldPop value for pregnancy density of grid i. Gj is the sum of the grid values for WorldPop in province or provincial capital j, and Tj is the actual number of women of reproductive age in province or provincial capital j from the Statistical Yearbook 2018 of Mozambique [23]:

    Analysis of Spatial Accessibility (Establishment of Geo-Database)

    ArcGIS (version 10.5; Esri, Inc) was used to calculate spatial access to CMPHS in this study. A geodatabase incorporating supply side data, demand side data, and administrative boundary data was first generated [43].

    Calculation of the Shortest Travel Time Needed to Reach ANC, ID, and PNC

    The nearest-neighbor method (NMM) was used to calculate the shortest travel time necessary to access ANC, ID, and PNC [44]. For each grid of women of reproductive age, only the nearest health care facility was considered [41]. The travel mode of walking at a speed of 4 km/h for spatial accessibility assessment and a threshold of 2 hours were used as criteria for timely access (Multimedia Appendix 1, Table S3) [5]. Additionally, the travel time along the straight-line distance was used to compare the travel time criterion [18,45]. The shortest travel time needed to reach ANC, ID, and PNC was calculated separately, and the average travel time was calculated for each province or provincial capital.

    Overlap Analysis of Spatial Coverage of CMPHS

    An overlap analysis was applied to identify multilevel health care access zones. On the basis of identifying areas able to access ANC, ID, and PNC in a timely manner (ie, within a 2 h threshold), 3 layers representing timely access to ANC, ID, and PNC, respectively, were overlapped to generate 8 types of multilevel health care access zones. Then, percentages for area and women of reproductive age covered within each type of multilevel health care access zone were calculated.

    Ethical Considerations

    The study was approved by the Swiss Confederation, represented by the Swiss Federal Department of Foreign Affairs, acting through the Swiss Agency for Development and Cooperation Global Cooperation Department and Southern Medical University of the People’s Republic of China (81067392). Core data used in this study were derived from the National Survey on Infrastructure, Equipment, Human Resources and Health Services 2018, which was collected between February and April 2018 through a cross-sectional survey of health care facilities. The survey included a census of all health facilities in the country and collected data through interviews with key informants at health care facilities. The core standard Service Availability and Readiness Assessment (SARA) questionnaire of the WHO was used and adapted to the Mozambique context [37,38]. The SARA questionnaire and linked protocols were granted approval by Mozambique’s Ministry of Health. More information about the primary data collection procedures is available in the Mozambique SARA 2018 report [38]. Permission to use the data was obtained from Mozambique’s Ministry of Health by coauthors from Mozambique. Other data, including population distribution and administrative boundaries, were extracted from publicly available data sets. No human participants or animals were involved in the study.


    Identification and Coverage of Indicators Representing CMPHS

    The identified indicators for the 3 service packages and the percentage of health care facilities capable of providing each service (indicators) are shown in Table 2. Among all health care facilities (N=1542), 784 were able to provide ANC, 365 were able to provide ID, and 299 were able to provide PNC.

    Most health care facilities within the study area managed to cover all services listed in each individual service package, with some indicators having fairly good penetration. The provision of intermittent preventive treatment in pregnancy for malaria, a component of the ANC service package, was offered in 1408 (91.31%) health care facilities. Conversely, some indicators showed suboptimal coverage; for example, emergency obstetric care was available in only 504 (32.68%) health care facilities and injectable antibiotics intended for neonatal sepsis were available in just 766 (49.68%) health care facilities (Table 2).

    Table 2. Identified indicators of the 3 service packages and the percentage of health care facilities able to provide each service (indicators) based on global guidelines for maternal, newborn, and child health, as well as pregnancy, childbirth, postpartum, and newborn care proposed by the World Health Organization and data extracted from the National Survey on Infrastructure, Equipment, Human Resources and Health Services 2018.
    Phases and key indicatorsHealth care facilities providing antenatal care, institutional delivery, and postnatal care (N=1542), n (%)
    Antenatal care (n=7 indicators; n=784 health care facilities)

    		Iron supplementation1070 (69.39)

    		Folic acid supplementation1035 (67.12)

    		Tetanus toxoid vaccination1364 (88.46)

    		Monitoring for hypertensive disorder of pregnancy1198 (77.69)

    		IPTpa for malaria1408 (91.31)

    		HIV counseling and testing for HIV-positive pregnant women1369 (88.78)

    		Antiviral treatment for HIV-positive pregnant women1347 (87.35)
    Institutional delivery(n=8 indicators; n=365 health care facilities)

    		Monitoring of labor with partograph1273 (82.56)

    		Parenteral administration of oxytocin1243 (80.61)

    		Assisted vaginal delivery1125 (72.96)

    		Manual removal of placenta1103 (71.53)

    		Antibiotics for preterm849 (55.06)

    		Blank partograph1204 (78.08)

    		Parenteral administration of magnesium sulfate1079 (69.97)

    		Emergency obstetric care504 (32.68)
    Postnatal care (n=10 indicators; n=299 health care facilities)

    		Immediate and exclusive breastfeeding1313 (85.15)

    		Thermal protection1293 (83.85)

    		Hygenic cord care1307 (84.76)

    		Neonatal resuscitation1122 (72.76)

    		Kangaroo mother care1094 (70.95)

    		Injectable antibiotics for neonatal sepsis766 (49.68)

    		HIV counseling and testing for infants born to HIV-positive women1351 (87.61)

    		ARVb prophylaxis to newborns of HIV-positive pregnant women1345 (87.22)

    		HIV-positive infant and young child feeding counseling1367 (88.65)

    		BCGc vaccine886 (57.46)

    aIPTp: intermittent preventive treatment in pregnancy.

    bARV: AIDS-related virus.

    cBCG: bacillus Calmette-Guérin.

    Distribution of Health Care Facilities Providing CMPHS

    There were 1542 health care facilities in total across the study area, among which were 1490 primary-level health care facilities (urban and rural health centers or community health posts), 43 secondary-level health care facilities (rural, district, and general hospitals), and 9 tertiary-level health care facilities (central and provincial hospitals or specialized and military hospitals). Among the primary-level facilities, 51.48% (767/1490), 21.34% (318/1490), and 18.46% (275/1490) were able to provide ANC, ID, and PNC, respectively. For the secondary facilities, the respective percentages were 37% (16/43), 91% (39/43), and 23% (17/43). For the tertiary-level health care facilities, the respective percentages were 11% (1/9), 89% (8/9), and 78% (7/9).

    Figure 2 shows the spatial distribution of the 3 levels of health care facilities able to deliver the 3 service packages. The spatial distribution of different levels of health care facilities able to provide ANC, ID, and PNC, respectively, is shown in Multimedia Appendix 1, Figure S2.

    ‎
    Figure 2. Capability of delivering the 3 service packages of continuous maternal and perinatal health care services was identified for every health care facility on the supply side. The WorldPop data set was used to provide spatial distribution of pregnant women at a 1×1 km2 resolution on the demand side. (A) The spatial distribution of women of reproductive age (people/0.01 km2). (B) The spatial distribution of the 3 levels of health care facilities in Mozambique in 2018. Maputo and Maputo City are displayed in the figures separately.

    Spatial Access to The 3 Service Packages of CMPHS

    In Mozambique, the median shortest travel times needed to access ANC, ID, and PNC were 2.38 (IQR 1.38-3.89) hours, 3.69 (IQR 1.87-5.28) hours, and 4.16 (IQR 2.48-6.67) hours, respectively. The shortest travel times required to reach the nearest health care facilities offering these services varied significantly across different regions. For ANC services, the shortest travel time ranged from 0.46 (IQR 0.26-0.69) hours in Maputo City to 4.95 (IQR 3.03-7.21) hours in Manica province. For ID services, it ranged from 0.74 (IQR 0.47-1.04) hours in Maputo City to 18.20 (IQR 11.67-24.65) hours in Niassa province. For PNC services, the shortest travel time ranged from 1.34 (IQR 0.83-1.85) hours in Maputo City to 10.76 (IQR 7.53-13.66) hours in Inhambane province. Except for Manica province, the shortest travel time needed to access ID was greater than for ANC in all other provinces. The shortest travel time spent to access ID was found to be distinctly longer than that for PNC in 3 provinces, namely Gaza, Maputo, and Niassa (Table 3).

    The results for coverage of different services in Figure 3 shows that women of reproductive age living in Maputo City were able to obtain timely ANC, ID, and PNC. Conversely, multiple provinces with lower population density were recognized as underserved areas, including the provinces of Niassa, Cabo Delgado, Gaza, and Inhambane, especially for the provision of ID and PNC.

    Table 3. The shortest travel time spent to reach antenatal care, institutional delivery, and postnatal care was calculated for different regions using the nearest-neighbor method with a criterion of 2 hours’ walking, which was set under the scenario that demanders walked along a straight line with a speed of 4 km/hour.
    RegionTime to reach antenatal care (hours)Time to reach institutional delivery (hours)Time to reach postnatal care (hours)

    		Median (IQR)MaximumMedian (IQR)MaximumMedian (IQR)Maximum







    Mozambique2.38 (1.38-3.89)30.383.69 (1.87-5.28)60.274.16 (2.48-6.67)45.53
    Cabo Delgado4.01 (2.39-6.82)25.714.89 (2.89-8.40)33.664.78 (2.64-8.11)29.78
    Gaza2.90 (1.56-4.25)20.406.09 (3.71-8.64)27.624.39 (2.71-6.35)27.99
    Inhambane2.69 (1.49-3.91)16.954.43 (2.37-7.16)31.4610.76 (7.53-13.66)33.82
    Manica4.95 (3.03-7.21)27.483.17 (1.94-4.41)20.054.09 (2.67-5.67)20.05
    Maputo1.94 (1.03-3.02)18.923.07 (1.78-4.79)18.612.33 (1.37-3.53)18.14
    Maputo City0.46 (0.26-0.69)2.190.74 (0.47-1.04)2.311.34 (0.83-1.85)3.70
    Nampula2.13 (1.37-2.80)10.612.81 (1.77-4.08)13.814.37 (2.80-6.39)17.15
    Niassa4.07 (2.41-6.63)30.3818.20 (11.67-24.65)60.277.69 (4.74-13.05)44.27
    Sofala2.11 (1.29-3.10)18.164.90 (2.98-7.22)25.214.21 (2.46-6.25)22.28
    Tete3.87 (2.41-5.34)18.065.70 (3.58-8.19)23.865.51 (3.41-8.51)45.53
    Zambezia2.47 (1.52-3.63)12.833.78 (2.35-5.69)19.664.03 (2.56-5.95)16.76
    ‎
    Figure 3. The spatial coverage of antenatal care (ANC), institutional delivery (ID), and postnatal care (PNC) provided by different levels of health care facilities by walking along a straight line with a speed of 4 km/hour and the standard of 2-hour security service range. The coverage area (in terms of 2-hour travel time) for (A) ANC, (B) ID, and (C) PNC. Maputo and Maputo City are displayed in the figures separately.

    Classification and Identification of Underserved Areas for CMPHS

    For women of reproductive age in Mozambique, more than 21% (living in about 2.69% of Mozambique’s area) lived in type 1 areas (able to obtain timely CMPHS including ANC, ID, and PNC); more than 51% (living in 83.25% of Mozambique’s area) lived in type 8 areas (not able to obtain timely access to any service packages of CMPHS); only 27.5% (living in about 14.07% of Mozambique’s area) lived in type 2-7 areas (able to access 1 or 2 types of services of CMPHS). The second highest percentage of women of reproductive age fell within type 5 areas, indicating that approximately 10% (living in about 7.42% of Mozambique’s area) were able to obtain ANC services in a timely manner. The third highest percentage of women of reproductive age fell within type 2 areas, meaning that more than 9% (living in about 2.19% of Mozambique’s area) were able to reach ANC and PNC in a timely manner (Table 4).

    Table 4. Three layers representing timely access to antenatal care (ANC), institutional delivery (ID), and postnatal care (PNC), respectively, were overlapped to generate 8 types of multilevel health care access zones. The percentages by land area and by women of reproductive age covered within each type of multilevel health care access zone were calculated using an overlap analysis with a criterion of 2-hour security service range.
    TypeMultilevel health care access zonesLand area, %Population, %
    1Able to obtain timely CMPHSa, including ANC, ID, and PNC2.6921.1
    2Able to obtain timely ANC and ID2.199.7
    3Able to obtain timely ANC and PNC1.613.79
    4Able to obtain timely ID and PNC0.951.63
    5Able to obtain timely ANC7.429.96
    6Able to obtain timely ID1.031.47
    7Able to obtain timely PNC0.870.95
    8Not able to obtain timely CMPHS, including ANC, ID, and PNC83.2551.4

    aCMPHS: continuous maternal and perinatal health care services.

    As can be seen in Figure 4 and Multimedia Appendix 1, Figure S3, the coverage of CMPHS was low in Mozambique, especially in the provinces of Inhambane, Niassa, and Gaza. Maputo City was the only region that was able to provide timely CMPHS for women of reproductive age.

    ‎
    Figure 4. Overlay analysis of spatial access among women of reproductive age to continuous maternal and perinatal health care services (CMPHS) with a criterion of a 2-hour secure service range. Multilevel health care access zones are areas able to access all 3 service packages, 2 of the 3 service packages, only 1 of the 3 service packages, or none of the 3 service packages. Green is used to represent full access to CMPHS (ie, a good service type, namely type 1), shades of yellow are used to represent access to any 2 types of service (ie, medium service types, namely type 2, type 3, and type 4), shades of red are used to represent access to any 1 type of service (ie, poorer service types, namely type 5, type 6, and type 7), and the blank areas represent no access to any type of services (ie, the poorest service type, namely type 8). Maputo and Maputo City are displayed in the figure separately. ANC: antenatal care; ID: institutional delivery; PNC: postnatal care.

    Principal Findings

    Our study proposed a 2-step procedure to assess the spatial accessibility of CMPHS and verified its applicability through a case study in Mozambique. The results first showed spatial access to different types of CMPHS and disparities among different service packages. By using an overlay analysis, this procedure could identify 7 types of underserved areas and the detailed spatial distribution of existing well-served areas. The results from this procedure have evidence-based implications to inform decision-making processes related to health resource allocation, particularly in low-resource settings confronted with similar challenges. This can ultimately aid in improving maternal and newborn health outcomes. The necessity of enhancing spatial accessibility as a critical solution to improve coverage of CMPHS is also highlighted. In the specific case of Mozambique, only 21% of women of reproductive age could access CMPHS in a timely manner, and these women were predominately clustered in the most-developed region, Maputo City. This highlights that spatial access to CMPHS remains a significant challenge and that improvements in the coverage of ID and PNC are urgently needed.

    Large disparities among regions in accessing CMPHS were also a critical issue. Inequities in CMPHS exist at the national, provincial, and district levels and always present fundamental barriers to progress, particularly among the most disadvantaged population groups [46]. This has been validated by our findings that the provinces of both Niassa and Cabo Delgado, which have lower population densities, tended to be more underserved, especially in accessing ID and PNC service packages. Our study also found that Maputo City was the only administrative unit that was capable of providing effective access to all the 3 service packages. We assume this is mainly because Maputo City is the capital of Maputo and the economic and social development center of Mozambique, so its development status far exceeds all the other areas [47]. In addition, the frequent occurrence of natural disasters, which greatly hinders health care service delivery, further adds to health inequities between the southern and northern regions in Mozambique, leading to lower rates of both ANC and ID visits in the southern region, corresponding to 74 additional maternal deaths and 726 additional deaths of children under the age of 1 month by the end of 2021 [48].

    In the context of Mozambique’s poor accessibility and low equity in health care, the implementation of a decentralized allocation strategy to address the inequity issue has been recognized as an effective measure to promote both accessibility and coverage of CMPHS, which can take China’s successful experiences as an example [49,50]. China has made remarkable achievements and passed milestones in achieving SDGs through implementing a decentralized allocation strategy to improve accessibility and equality of health care services. China clearly indicated that women and children were target groups in the cooperation for global health in the Belt and Road Initiative in 2017 and implemented 100 foreign assistance programs for women and children’s health in low-income countries, so decentralized allocation strategies from China can help low-income countries improve their own CMPHS [51]. For example, strategies for the promotion of primary health care, along with the optimization of a hierarchical health care delivery system intended for maternal and child health care, were implemented. According to these strategies, integrated service packages delivered via the collaborative efforts of tertiary hospitals and primary maternal health care facilities proved to be an effective solution to strengthen the capacity of local health care facilities, as well as their corresponding referral systems, which resulted in increased in-hospital births and significantly reduced maternal mortality [50,52,53]. Furthermore, community-based interventions with components to engage or mobilize communities have been increasingly implemented to improve maternal and newborn health outcomes in low-resource settings [54-56]. For example, training programs should be provided to cultivate highly skilled health care professionals among local health care facilities [55,57].

    Comparison With Prior Work

    Few studies have assessed the spatial accessibility of health care resources in Mozambique. A previous study reported that 67.3% of Mozambique’s population lived outside a 1-hour travel distance from primary health care centers [58]. However, spatial barriers to accessing health care services are gaining increasing attention. According to the Statistical Yearbook 2018 of Mozambique, the average travel distance needed to access a health care facility for people living in remote areas was 12.3 km [34]. The 2018-2019 Mozambique Humanitarian Response Plan reported that about 50% of the population lived more than 20 km away from the nearest health care facility [59]. Given the national focus on maternal and perinatal health, studies assessing spatial access to CMPHS have been carried out in the context of low-resource settings [14,17,60]. Previous findings suggest that 49.8% of women of reproductive age in Mozambique lived outside a 2-hour travel area from the nearest hospital for emergency services [61]. In southern Mozambique, 46% of pregnant women were able to access the nearest primary health care facility within 1 hour by walking, while 64% of women living in the region could receive life-saving service delivery within 2 hours [46]. While most existing literature has only assessed spatial access to single services, our results are consistent with previous findings that spatial access to maternal and perinatal health care services is poor in Mozambique. Moreover, our study further considered 3 separate service packages, representing important stages in the continuity of maternal and perinatal health care services, revealing spatial access to CMPHS in a straightforward manner.

    Public Health Implications

    Our findings provide important evidence on the development of tailored, country-specific policies and interventions to address the geographical disparities of CMPHS in low-resource settings, which can support the development of resource allocation strategies based on the priority of CMPHS delivery. Using Mozambique as a case study of a low-resource setting, we recommend that public health policy makers and decision-makers draw from successful lessons such as decentralized allocation strategies. Through a comprehensive understanding of the geographical barriers to access to CMPHS, these strategies can quickly and efficiently improve maternal and neonatal health outcomes and contribute to the achievement of SDG3 and UHC.

    Limitations

    This study does have several limitations. First, we set a scenario of women of reproductive age walking to health care facilities to reflect the most basic requirement of the vast number of vulnerable people in Mozambique. Other travel modes were not considered due to data limitations and the complexity of factors influencing the choice of travel mode. Specific travel thresholds for different levels of health care facilities were also not set due to a lack of reference data. Second, we used the spatial distribution of women of reproductive age as demand-side data instead of pregnancies due to data availability. Third, the integration of indicators representing the 3 service packages failed to take into account the type of health care facilities providing each service. Consequently, the continuum of services in different health care facilities was not further analyzed.

    Conclusions

    Using Mozambique as a case study, this research used a 2-step procedure to assess the accessibility of CMPHS and proposes targeted policy suggestions for improving health outcomes. Further studies could be conducted, especially in low-resource settings, with reference to local context, and thus inform resource allocation–related decision-making procedures. In turn, this could potentially contribute to the improvement of global maternal and neonatal health, the realization of SDG3, and the attainment of UHC.

    Acknowledgments

    The authors are grateful to staff from the Mozambique National Institute of Health for providing data on health care facilities in Mozambique.

    Data Availability

    Data from the National Survey on Infrastructure, Equipment, Human Resources and Health Services 2018 can be accessed with approval from Mozambique’s Ministry of Health. Other data used in this study come from publicly available data sets with sources listed in the main text.

    Authors' Contributions

    QL and XW designed the study. QL, XW, and JP designed, had full access to, and verified the underlying data reported in the study. QL performed the data analysis and wrote the first draft with supervision from XW and JP. EK, IR, RMMC and EC provided suggestions on the data processing. DRX and YY helped revise the draft. All authors contributed to interpretation of data, revised the article critically for important intellectual content, and approved the final version of the manuscript.

    Conflicts of Interest

    None declared.

    Multimedia Appendix 1

    Supplementary Tables S1-S3 and Figures S1-S3.

    DOCX File , 2186 KB
    1. Trends in maternal mortality 2000 to 2020: estimates by WHO, UNICEF, UNFPA, World Bank Group and UNDESA/Population Division: executive summary. World Health Organization. URL: https://www.who.int/publications/i/item/9789240069251 [accessed 2024-06-05]
    2. Matthews Z, Rawlins B, Duong J, Molla YB, Moran AC, Singh K, et al. Geospatial analysis for reproductive, maternal, newborn, child and adolescent health: gaps and opportunities. BMJ Glob Health. 2019;4(Suppl 5):e001702. [FREE Full text] [CrossRef] [Medline]
    3. Alam N, Hajizadeh M, Dumont A, Fournier P. Inequalities in maternal health care utilization in sub-Saharan African countries: a multiyear and multi-country analysis. PLoS One. 2015;10(4):e0120922. [FREE Full text] [CrossRef] [Medline]
    4. Gandhi S, Ramesh S, Dash U, Babu SM. A systematic review of demand-based and supply-based interventions on continuum of maternal and child healthcare in south Asian countries. J Public Health (Berl.). Jan 13, 2020;29(4):857-870. [CrossRef]
    5. Hierink F, Rodrigues N, Muñiz M, Panciera R, Ray N. Modelling geographical accessibility to support disaster response and rehabilitation of a healthcare system: an impact analysis of Cyclones Idai and Kenneth in Mozambique. BMJ Open. Nov 03, 2020;10(11):e039138. [FREE Full text] [CrossRef] [Medline]
    6. Sakuma S, Yasuoka J, Phongluxa K, Jimba M. Determinants of continuum of care for maternal, newborn, and child health services in rural Khammouane, Lao PDR. PLoS One. 2019;14(4):e0215635. [FREE Full text] [CrossRef] [Medline]
    7. Delivering for women: improving maternal health services to save lives. UNICEF. URL: https://data.unicef.org/resources/delivering-for-women/ [accessed 2024-06-05]
    8. Chinkhumba J, De Allegri M, Muula AS, Robberstad B. Maternal and perinatal mortality by place of delivery in sub-Saharan Africa: a meta-analysis of population-based cohort studies. BMC Public Health. Sep 28, 2014;14(1):1014. [FREE Full text] [CrossRef] [Medline]
    9. Healthy mothers, healthy babies: Taking stock of maternal health. UNICEF. 2019. URL: https://data.unicef.org/resources/healthy-mothers-healthy-babies/ [accessed 2024-06-05]
    10. Heredia-Pi I, Serván-Mori E, Nigenda G, Sosa-Rubí SG, Reyes-Morales H. Early contraception and continuity of maternal health care in primiparous adolescents and young adults from low- and middle-income countries: the case of Mexico. Sex Res Soc Policy. Mar 30, 2022;19(3):991-1005. [CrossRef]
    11. More women and children survive today than ever before – UN report. World Health Organization. 2019. URL: https:/​/www.​who.int/​news/​item/​19-09-2019-more-women-and-children-survive-today-than-ever-before-un-report [accessed 2024-06-05]
    12. Perin J, Mulick A, Yeung D, Villavicencio F, Lopez G, Strong KL, et al. Global, regional, and national causes of under-5 mortality in 2000-19: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet Child Adolesc Health. Feb 2022;6(2):106-115. [FREE Full text] [CrossRef] [Medline]
    13. World Health Report 2005. Make every mother and child count. World Health Organization. URL: https://www.who.int/publications/i/item/9241562900 [accessed 2024-06-05]
    14. Wigley AS, Tejedor-Garavito N, Alegana V, Carioli A, Ruktanonchai CW, Pezzulo C, et al. Measuring the availability and geographical accessibility of maternal health services across sub-Saharan Africa. BMC Med. Sep 08, 2020;18(1):237. [FREE Full text] [CrossRef] [Medline]
    15. Keyes EB, Parker C, Zissette S, Bailey PE, Augusto O. Geographic access to emergency obstetric services: a model incorporating patient bypassing using data from Mozambique. BMJ Glob Health. 2019;4(Suppl 5):e000772. [FREE Full text] [CrossRef] [Medline]
    16. Llop-Gironés A, Julià M, Chicumbe S, Dulá J, Odallah AAP, Alvarez F, et al. Inequalities in the access to and quality of healthcare in Mozambique: evidence from the household budget survey. Int J Qual Health Care. Oct 31, 2019;31(8):577-582. [CrossRef] [Medline]
    17. Bobo FT, Asante A, Woldie M, Dawson A, Hayen A. Spatial patterns and inequalities in skilled birth attendance and caesarean delivery in sub-Saharan Africa. BMJ Glob Health. Oct 2021;6(10):e007074. [FREE Full text] [CrossRef] [Medline]
    18. Dotse-Gborgbortsi W, Tatem AJ, Matthews Z, Alegana VA, Ofosu A, Wright JA. Quality of maternal healthcare and travel time influence birthing service utilisation in Ghanaian health facilities: a geographical analysis of routine health data. BMJ Open. Jan 18, 2023;13(1):e066792. [FREE Full text] [CrossRef] [Medline]
    19. Birmeta K, Dibaba Y, Woldeyohannes D. Determinants of maternal health care utilization in Holeta town, central Ethiopia. BMC Health Serv Res. Jul 03, 2013;13(1):256. [FREE Full text] [CrossRef] [Medline]
    20. Stanton M, Higgs E, Koblinsky M. Investigating financial incentives for maternal health: an introduction. J Health Popul Nutr. Dec 2013;31(4 Suppl 2):1-7. [Medline]
    21. Delamater PL, Messina JP, Shortridge AM, Grady SC. Measuring geographic access to health care: raster and network-based methods. Int J Health Geogr. May 15, 2012;11(1):15. [FREE Full text] [CrossRef] [Medline]
    22. Human development report 2021-22. United Nations Development Programme. URL: https://hdr.undp.org/content/human-development-report-2021-22 [accessed 2024-06-05]
    23. mozambique's general population and housing census in 2017. Instituto Nacional de Estadística. 2018. URL: https://www.ine.gov.mz/web/guest/censo-2017 [accessed 2024-06-05]
    24. Egger E, Salvucci V, Tarp F. Evolution of multidimensional poverty in crisis-ridden Mozambique. Soc Indic Res. 2023;166(3):485-519. [FREE Full text] [CrossRef] [Medline]
    25. Households and NPISHs Final consumption expenditure (constant 2015 US$). World Bank. URL: https://data.worldbank.org/indicator/NE.CON.PRVT.KD [accessed 2024-06-05]
    26. Report on neonatal maternal deaths and in-hospital mortality. República de Moçambique Ministério da Saúde. 2020. URL: https:/​/www.​misau.gov.mz/​index.php/​relatorios-anuais-de-auditoria-de-mortes-maternas-e-neonatais-e-de-mortalidade-intra-hospitalar [accessed 2024-06-05]
    27. Amosse F, Boene H, Kinshella MW, Drebit S, Sharma S, Makanga PT, et al. Implementation of a community transport strategy to reduce delays in seeking obstetric care in rural Mozambique. Glob Health Sci Pract. Mar 15, 2021;9(Suppl 1):S122-S136. [FREE Full text] [CrossRef] [Medline]
    28. Wang X, Yang H, Duan Z, Pan J. Spatial accessibility of primary health care in China: A case study in Sichuan Province. Soc Sci Med. Jul 2018;209:14-24. [CrossRef] [Medline]
    29. Tian F, Pan J. Hospital bed supply and inequality as determinants of maternal mortality in China between 2004 and 2016. Int J Equity Health. Jan 30, 2021;20(1):51. [FREE Full text] [CrossRef] [Medline]
    30. Pan J, Zhao H, Wang X, Shi X. Assessing spatial access to public and private hospitals in Sichuan, China: The influence of the private sector on the healthcare geography in China. Soc Sci Med. Dec 2016;170:35-45. [CrossRef] [Medline]
    31. Pregnancy, childbirth, postpartum and newborn care: A guide for essential practice (3rd edition). World Health Organization. 2015. URL: https://www.who.int/publications/i/item/9789241549356 [accessed 2024-06-05]
    32. Improving the quality of care for maternal, newborn and child health: implementation guide for national, district and facility levels. World Health Organization. URL: https://iris.who.int/handle/10665/353738 [accessed 2024-06-05]
    33. Public health facilities in sub Saharan Africa. Figshare. Dataset. URL: https://doi.org/10.6084/m9.figshare.7725374.v1 [accessed 2024-06-05]
    34. República DMMDS. Statistical Yearbook 2018. Anuários Estatísticos. 2019. URL: https://old.misau.gov.mz/index.php/anuarios-estatistico?limitstart=0 [accessed 2024-06-10]
    35. Pregnancies/Individual countries/Mozambique 1000m. WorldPop Hub. URL: https://hub.worldpop.org/geodata/summary?id=995 [accessed 2024-06-05]
    36. OpenStreetMap. URL: https://www.openstreetmap.org/ [accessed 2024-06-05]
    37. Maulide CR, Sheffel A, Salomão C, Sambo J, Matusse E, Ismail E. Structural readiness of health facilities in Mozambique: how is Mozambique positioned to deliver nutrition-specific interventions to women and children? J Glob Health Rep. 2023:7. [CrossRef]
    38. SARA 2018: inventário nacional. World Health Organization. URL: https://www.afro.who.int/fr/node/12239 [accessed 2024-06-05]
    39. Kerber KJ, de Graft-Johnson JE, Bhutta ZA, Okong P, Starrs A, Lawn JE. Continuum of care for maternal, newborn, and child health: from slogan to service delivery. Lancet. Oct 13, 2007;370(9595):1358-1369. [CrossRef] [Medline]
    40. Wang X, Seyler BC, Han W, Pan J. An integrated analysis of spatial access to the three-tier healthcare delivery system in China: a case study of Hainan Island. Int J Equity Health. Feb 12, 2021;20(1):60. [FREE Full text] [CrossRef] [Medline]
    41. Pan J, Liu H, Wang X, Xie H, Delamater PL. Assessing the spatial accessibility of hospital care in Sichuan Province, China. Geospat Health. Nov 27, 2015;10(2):384. [FREE Full text] [CrossRef] [Medline]
    42. Wang X, Pan J. Assessing the disparity in spatial access to hospital care in ethnic minority region in Sichuan Province, China. BMC Health Serv Res. Aug 17, 2016;16(1):399. [FREE Full text] [CrossRef] [Medline]
    43. Deng Y, Zhang Y, Pan J. Optimization for locating emergency medical service facilities: a case study for health planning from China. Risk Manag Healthc Policy. 2021;14:1791-1802. [FREE Full text] [CrossRef] [Medline]
    44. Noor AM, Amin AA, Gething PW, Atkinson PM, Hay SI, Snow RW. Modelling distances travelled to government health services in Kenya. Trop Med Int Health. Feb 2006;11(2):188-196. [FREE Full text] [CrossRef] [Medline]
    45. Alegana VA, Wright JA, Pentrina U, Noor AM, Snow RW, Atkinson PM. Spatial modelling of healthcare utilisation for treatment of fever in Namibia. Int J Health Geogr. Feb 15, 2012;11:6. [FREE Full text] [CrossRef] [Medline]
    46. Makanga PT, Schuurman N, Sacoor C, Boene HE, Vilanculo F, Vidler M, et al. Seasonal variation in geographical access to maternal health services in regions of southern Mozambique. Int J Health Geogr. Jan 13, 2017;16(1):1. [FREE Full text] [CrossRef] [Medline]
    47. Barletta G, Castigo F, Egger E, Keller M, Salvucci V, Tarp F. The impact of COVID-19 on consumption poverty in Mozambique. J Int Dev. May 2022;34(4):771-802. [FREE Full text] [CrossRef] [Medline]
    48. Stone B, Sambo J, Sawadogo-Lewis T, Roberton T. When it rains, it pours: detecting seasonal patterns in utilization of maternal healthcare in Mozambique using routine data. BMC Health Serv Res. Oct 15, 2020;20(1):950. [FREE Full text] [CrossRef] [Medline]
    49. Souza J, Tunçalp Ö, Vogel J, Bohren M, Widmer M, Oladapo O, et al. Obstetric transition: the pathway towards ending preventable maternal deaths. BJOG. Mar 2014;121 Suppl 1:1-4. [CrossRef] [Medline]
    50. Chen N, Pan J. The causal effect of delivery volume on severe maternal morbidity: an instrumental variable analysis in Sichuan, China. BMJ Glob Health. May 2022;7(5):e008428. [FREE Full text] [CrossRef] [Medline]
    51. Qiao J, Wang Y, Li X, Jiang F, Zhang Y, Ma J, et al. A Lancet Commission on 70 years of women's reproductive, maternal, newborn, child, and adolescent health in China. Lancet. Jun 26, 2021;397(10293):2497-2536. [CrossRef] [Medline]
    52. Li X, Krumholz HM, Yip W, Cheng KK, De Maeseneer J, Meng Q, et al. Quality of primary health care in China: challenges and recommendations. Lancet. Jun 06, 2020;395(10239):1802-1812. [FREE Full text] [CrossRef] [Medline]
    53. Tao Z, Han W. Assessing the impacts of hierarchical healthcare system on the accessibility and spatial equality of healthcare services in Shenzhen, China. ISPRS Int J Geoinf. Sep 16, 2021;10(9):615. [CrossRef]
    54. Dada S, Cocoman O, Portela A, De Brún A, Bhattacharyya S, Tunçalp Ö, et al. What's in a name? Unpacking 'Community ' terminology in reproductive, maternal, newborn and child health: a scoping review. BMJ Glob Health. Feb 2023;8(2):e009423. [FREE Full text] [CrossRef] [Medline]
    55. Amosse F, Kinshella MW, Boene H, Sharma S, Nhamirre Z, Tchavana C, et al. CLIP Mozambique Working Group. The development and implementation of a community engagement strategy to improve maternal health in southern Mozambique. PLOS Glob Public Health. 2023;3(1):e0001106. [FREE Full text] [CrossRef] [Medline]
    56. Gwacham-Anisiobi U, Boo YY, Oladimeji A, Kurinczuk JJ, Roberts N, Opondo C, et al. Types, reporting and acceptability of community-based interventions for stillbirth prevention in sub-Saharan Africa (SSA): a systematic review. EClinicalMedicine. Aug 2023;62:102133. [FREE Full text] [CrossRef] [Medline]
    57. Mason E, Mathai M, Silvestre MA. Time of transition: lessons from China's progress in reproductive, maternal, newborn, child, and adolescent health. Lancet. Jun 26, 2021;397(10293):2444-2447. [CrossRef] [Medline]
    58. Dos Anjos Luis A, Cabral P. Geographic accessibility to primary healthcare centers in Mozambique. Int J Equity Health. Oct 18, 2016;15(1):173. [FREE Full text] [CrossRef] [Medline]
    59. 2018-2019 Mozambique humanitarian response plan revised following cyclones Idai and Kenneth, May 2019 (November 2018 - June 2019). United Nations Office of Coordinated Humanitarian Affairs. 2019. URL: https:/​/reliefweb.​int/​report/​mozambique/​2018-2019-mozambique-humanitarian-response-plan-revised-following-cyclones-idai [accessed 2024-06-05]
    60. Alamneh TS, Teshale AB, Yeshaw Y, Alem AZ, Ayalew HG, Liyew AM, et al. Barriers for health care access affects maternal continuum of care utilization in Ethiopia; spatial analysis and generalized estimating equation. PLoS One. 2022;17(4):e0266490. [FREE Full text] [CrossRef] [Medline]
    61. Ouma PO, Maina J, Thuranira PN, Macharia PM, Alegana VA, English M, et al. Access to emergency hospital care provided by the public sector in sub-Saharan Africa in 2015: a geocoded inventory and spatial analysis. Lancet Glob Health. Mar 2018;6(3):e342-e350. [FREE Full text] [CrossRef] [Medline]

    ‎
    ANC: antenatal care
    CMPHS: continuous maternal and perinatal health care services
    ID: institutional delivery
    MNCH: maternal, newborn, and child health
    NNM: nearest-neighbor method
    PCPNC: pregnancy, childbirth, postpartum and newborn care
    PNC: postnatal care
    SARA: Service Availability and Readiness Assessment
    SDG3: sustainable development goal 3
    SSA: sub-Saharan Africa
    UHC: universal health coverage
    WHO: World Health Organization

    Edited by A Mavragani; submitted 26.05.23; peer-reviewed by X Zhou, Y Sun; comments to author 04.10.23; revised version received 26.11.23; accepted 07.05.24; published 18.07.24.

    Copyright

    ©Qin Li, Elsa Kanduma, Isaías Ramiro, Dong (Roman) Xu, Rosa Marlene Manjate Cuco, Eusebio Chaquisse, Yili Yang, Xiuli Wang, Jay Pan. Originally published in JMIR Public Health and Surveillance (https://publichealth.jmir.org), 18.07.2024.

    This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Public Health and Surveillance, is properly cited. The complete bibliographic information, a link to the original publication on https://publichealth.jmir.org, as well as this copyright and license information must be included.