Correlation Between Opioid Drug Prescription and Opioid-Related Mortality in Spain as a Surveillance Tool: Ecological Study

Alejandro Salazar   ^{1, 2, 3} , PhD ;   Soledad Moreno-Pulido   ⁴ , PhD ;   Pablo Prego-Meleiro   ^{5, 6} , PhD ;   Jesús Henares-Montiel   ^{7, 8} , PhD ;   José Pulido   ^{5, 7} , PhD ;   Marta Donat   ⁹ , PhD ;   Gabriel Sotres-Fernandez   ^{10, 11} , MD ;   Luis Sordo   ^{5, 7} , PhD

¹ Observatory of Pain, University of Cádiz, Cádiz, Spain

² Biomedical Research and Innovation Institute of Cádiz (INiBICA), Research Unit, Puerta del Mar University Hospital, University of Cadiz, Cádiz, Spain

³ Department of Statistics and Operational Research, University of Cádiz, Puerto Real, Spain

⁴ Department of Mathematics, University of Cádiz, Puerto Real, Spain

⁵ Department of Public Health and Maternal-Child Health, Faculty of Medicine, Complutense University of Madrid, Madrid, Spain

⁶ Department of Analytical Chemistry, Physical Chemistry and Chemical Engineering, Faculty of Pharmacy, University of Alcalá, Alcalá de Henares, Spain

⁷ Center for Biomedical Research in Epidemiology and Public Health (CIBER), Madrid, Spain

⁸ Andalusian School of Public Health, Granada, Spain

⁹ National School of Health, Salud Carlos III Health Institute, Madrid, Spain

¹⁰ Oncology Department, Hospital Quirón Salud, Madrid, Spain

¹¹ Department of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain