Published on in Vol 6, No 2 (2020): Apr-Jun

Preprints (earlier versions) of this paper are available at, first published .
Delivering Benefits at Speed Through Real-World Repurposing of Off-Patent Drugs: The COVID-19 Pandemic as a Case in Point

Delivering Benefits at Speed Through Real-World Repurposing of Off-Patent Drugs: The COVID-19 Pandemic as a Case in Point

Delivering Benefits at Speed Through Real-World Repurposing of Off-Patent Drugs: The COVID-19 Pandemic as a Case in Point


  1. Pillaiyar T, Wendt L, Manickam M, Easwaran M. The recent outbreaks of human coronaviruses: A medicinal chemistry perspective. Medicinal Research Reviews 2021;41(1):72 View
  2. Infante M, Ricordi C, Alejandro R, Caprio M, Fabbri A. Hydroxychloroquine in the COVID-19 pandemic era: in pursuit of a rational use for prophylaxis of SARS-CoV-2 infection. Expert Review of Anti-infective Therapy 2021;19(1):5 View
  3. Mostafa T. Could Oral Phosphodiesterase 5 Inhibitors Have a Potential Adjuvant Role in Combating COVID-19 Infection?. Sexual Medicine Reviews 2021;9(1):15 View
  4. Lisi L, Lacal P, Barbaccia M, Graziani G. Approaching coronavirus disease 2019: Mechanisms of action of repurposed drugs with potential activity against SARS-CoV-2. Biochemical Pharmacology 2020;180:114169 View
  5. Heffernan K, Ranadive S, Jae S. Exercise as medicine for COVID-19: On PPAR with emerging pharmacotherapy. Medical Hypotheses 2020;143:110197 View
  6. Mondaini N. Phosphodiesterase Type 5 Inhibitors and COVID-19: Are They Useful In Disease Management?. The World Journal of Men's Health 2020;38(3):254 View
  7. Cadegiani F. Repurposing existing drugs for COVID-19: an endocrinology perspective. BMC Endocrine Disorders 2020;20(1) View
  8. Tyagi S, Singh M. Multi-organ damage by covid-19: congestive (cardio-pulmonary) heart failure, and blood-heart barrier leakage. Molecular and Cellular Biochemistry 2021;476(4):1891 View
  9. Ennis M, Tiligada K. Histamine receptors and COVID-19. Inflammation Research 2021;70(1):67 View
  10. Yeramaneni S, Doshi P, Sands K, Cooper M, Kurbegov D, Fromell G. Famotidine Use Is Not Associated With 30-day Mortality: A Coarsened Exact Match Study in 7158 Hospitalized Patients With Coronavirus Disease 2019 From a Large Healthcare System. Gastroenterology 2021;160(3):919 View
  11. Rios C, Cassatt D, Hollingsworth B, Satyamitra M, Tadesse Y, Taliaferro L, Winters T, DiCarlo A. Commonalities Between COVID-19 and Radiation Injury. Radiation Research 2020;195(1) View
  12. Rogosnitzky M, Berkowitz E, Jadad A. No Time to Waste: Real-World Repurposing of Generic Drugs as a Multifaceted Strategy Against COVID-19. JMIRx Med 2020;1(1):e19583 View
  13. Reznikov L, Norris M, Vashisht R, Bluhm A, Li D, Liao Y, Brown A, Butte A, Ostrov D. Identification of antiviral antihistamines for COVID-19 repurposing. Biochemical and Biophysical Research Communications 2021;538:173 View
  14. Motta N, Autran L, Brazão S, Lopes R, Scaramello C, Lima G, Brito F. Could cilostazol be beneficial in COVID-19 treatment? Thinking about phosphodiesterase-3 as a therapeutic target. International Immunopharmacology 2021;92:107336 View
  15. Dabbish A, Yonis N, Salama M, Essa M, Qoronfleh M. Inflammatory pathways and potential therapies for COVID-19: A mini review. European Journal of Inflammation 2021;19:205873922110029 View
  16. Kifle Z, Ayele A, Enyew E, Broecker F. Drug Repurposing Approach, Potential Drugs, and Novel Drug Targets for COVID-19 Treatment. Journal of Environmental and Public Health 2021;2021:1 View
  17. Caiazza R, Phan P, Lehmann E, Etzkowitz H. An absorptive capacity-based systems view of Covid-19 in the small business economy. International Entrepreneurship and Management Journal 2021;17(3):1419 View
  18. Pawar A, Pal A, Goswami K, Squitti R, Rongiolettie M. Molecular basis of quercetin as a plausible common denominator of macrophage-cholesterol-fenofibrate dependent potential COVID-19 treatment axis. Results in Chemistry 2021;3:100148 View
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  23. Mahdiraji H, Kamardi A, Beheshti M, Hajiagha S, Rocha-Lona L. Analysing supply chain coordination mechanisms dealing with repurposing challenges during Covid-19 pandemic in an emerging economy: a multi-layer decision making approach. Operations Management Research 2022;15(3-4):1341 View
  24. Shamohammadi I, Kazemeyni S, Sadighi M, Hasanzadeh T, Dizavi A. Efficacy of tadalafil on improvement of men with erectile dysfunction caused by COVID-19: A randomized placebo-controlled trial. Asian Journal of Urology 2024;11(1):128 View
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Books/Policy Documents

  1. Mohanty C, Vinod C, Acharya S, Mahapatra N. Modeling, Control and Drug Development for COVID-19 Outbreak Prevention. View
  2. Rogosnitzky M. Drug Repurposing. View
  3. Altuntas F. Using Crises and Disasters as Opportunities for Innovation and Improvement. View