Social Media Impact of the Food and Drug Administration's Drug Safety Communication Messaging About Zolpidem: Mixed-Methods Analysis

Michael S Sinha   ¹ , MD, JD, MPH ;   Clark C Freifeld   ² , PhD ;   John S Brownstein   ³ , PhD ;   Macarius M Donneyong   ⁴ , MPH, PhD ;   Paula Rausch   ⁵ , PhD, RN ;   Brian M Lappin   ⁵ , MA ;   Esther H Zhou   ⁵ , MD, PhD ;   Gerald J Dal Pan   ⁵ , MD, MHS ;   Ajinkya M Pawar   ¹ , PhD ;   Thomas J Hwang   ¹ ;   Jerry Avorn   ¹ , MD ;   Aaron S Kesselheim   ¹ , MD, JD, MPH

¹ Program On Regulation, Therapeutics, And Law, Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States

² College of Computer and Information Science, Northeastern University, Boston, MA, United States

³ Computational Epidemiology Group, Boston Children's Hospital, Boston, MA, United States

⁴ Health Services Management and Policy, College of Public Health, The Ohio State University, Columbus, OH, United States

⁵ Food and Drug Administration, Silver Spring, MD, United States