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Scaling Up and Enhancing the Functionality of the Electronic Integrated Diseases Surveillance and Response System in Uganda, 2020-2022: Description of the Journey, Challenges, and Lessons Learned

Scaling Up and Enhancing the Functionality of the Electronic Integrated Diseases Surveillance and Response System in Uganda, 2020-2022: Description of the Journey, Challenges, and Lessons Learned

Uganda is highly susceptible to public health emergencies due to its proximity to the ecologically diverse and biologically rich tropical Congo Basin, recurrent epidemic-prone outbreaks, and refugee inflow [1]. In the last 5 years before 2024, Uganda has faced several significant outbreaks, including Ebola and Marburg virus diseases, cholera, measles, and Crimean-Congo hemorrhagic fever, highlighting the ongoing threat of infectious diseases [2].

Rodney Mugasha, Andrew Kwiringira, Vivian Ntono, Lydia Nakiire, Immaculate Ayebazibwe, Caroline Kyozira, Allan Niyonzima Muruta, Juliet Namugga Kasule, Dathan M Byonanebye, Judith Nanyondo, Richard Walwema, Francis Kakooza, Mohammed Lamorde

JMIR Public Health Surveill 2025;11:e59783

Integration of a Patient-Centered mHealth Intervention (Support-Moms) Into Routine Antenatal Care to Improve Maternal Health Among Pregnant Women in Southwestern Uganda: Protocol for a Randomized Controlled Trial

Integration of a Patient-Centered mHealth Intervention (Support-Moms) Into Routine Antenatal Care to Improve Maternal Health Among Pregnant Women in Southwestern Uganda: Protocol for a Randomized Controlled Trial

Fixed SMS data are stored in a secure cloud, which is Health Insurance Portability and Accountability Act (HIPAA) compliant. i Streams-Uganda works in partnership with Africa’s Talking, a platform that facilitates access to a telco infrastructure that uses automated SMS, voice, airtime, and other application programming interfaces—mechanisms tested and successfully used during our pilot study. This automated technology for SMS [23,25] and calls [36,63] has also been used for other studies in Uganda.

Esther Cathyln Atukunda, Godfrey Rwambuka Mugyenyi, Jessica E Haberer, Mark J Siedner, Angella Musiimenta, Josephine N Najjuma, Celestino Obua, Lynn T Matthews

JMIR Res Protoc 2025;14:e67049

Characterizing Telehealth Barriers and Preferences to Promote Acceptable Implementation Strategies in Central Uganda: Multilevel Formative Evaluation

Characterizing Telehealth Barriers and Preferences to Promote Acceptable Implementation Strategies in Central Uganda: Multilevel Formative Evaluation

Thus, the purpose of this study was to conduct a multi-level formative evaluation identifying barriers and facilitators for implementing telehealth among health service providers and patients in Central Uganda.

Michael Kizito, Erina Nabunjo Mugabi, Sabrina Ford, Bree Holtz, Kelly Hirko

JMIR Form Res 2025;9:e60843

Effectiveness of a Mobile Health Intervention (DOT Selfie) in Increasing Treatment Adherence Monitoring and Support for Patients With Tuberculosis in Uganda: Randomized Controlled Trial

Effectiveness of a Mobile Health Intervention (DOT Selfie) in Increasing Treatment Adherence Monitoring and Support for Patients With Tuberculosis in Uganda: Randomized Controlled Trial

Similarly, studies conducted among patients and health care providers in Uganda have shown that VDOT is feasible and acceptable for monitoring and supporting patients undergoing TB treatment [25,30,31]. A recent systematic review and meta-analysis found that VDOT is effective in improving medication adherence and bacteriological resolution compared with in-person DOT care [32].

Juliet Nabbuye Sekandi, Esther Buregyeya, Sarah Zalwango, Damalie Nakkonde, Patrick Kaggwa, Trang Ho Thu Quach, David Asiimwe, Lynn Atuyambe, Kevin Dobbin

JMIR Mhealth Uhealth 2025;13:e57991

A Narrative-Gamified Mental Health App (Kuamsha) for Adolescents in Uganda: Mixed Methods Feasibility and Acceptability Study

A Narrative-Gamified Mental Health App (Kuamsha) for Adolescents in Uganda: Mixed Methods Feasibility and Acceptability Study

The prevalence of common mental disorders among adolescents in Uganda is alarmingly high, with estimates reaching up to 25% [1-3]. When left unaddressed, common mental disorders such as depression and anxiety can profoundly impact the developmental trajectories of adolescents, with potentially long-lasting consequences that extend into adulthood [4].

Julia R Pozuelo, Christine Nabulumba, Doreen Sikoti, Meghan Davis, Joy Louise Gumikiriza-Onoria, Eugene Kinyanda, Bianca Moffett, Alastair van Heerden, Heather A O'Mahen, Michelle Craske, DoBAt & Ebikolwa Consortium, Munshi Sulaiman, Alan Stein

JMIR Serious Games 2024;12:e59381

Assessing the Usage and Usability of a Mental Health Advice Telephone Service in Uganda: Mixed Methods Study

Assessing the Usage and Usability of a Mental Health Advice Telephone Service in Uganda: Mixed Methods Study

Uganda, like many other low- and middle-income countries, faces a significant mental health burden and a substantial gap in mental health care. Approximately 1 in 3 Ugandans experience some form of mental illness, with depression (22.2%) and anxiety (20.2%) being the most prevalent [18,19]. Additionally, Uganda has one of the highest per-capita alcohol consumption rates, with alcohol and substance use disorders being widespread, particularly among men, while also affecting children and youth [20].

Johnblack K Kabukye, Juliet Nakku, Jackline Niwemuhwezi, James Nsereko, Rosemary Namagembe, Iris Dorothee Emilie Groen, Ritah Neumbe, Denis Mubiru, Caroline Kisakye, Roseline Nanyonga, Marie Sjölinder, Susanne Nilsson, Caroline Wamala-Larsson

J Med Internet Res 2024;26:e65692

Leveraging Ecological Momentary Assessment Data to Characterize Individual Mobility: Exploratory Pilot Study in Rural Uganda

Leveraging Ecological Momentary Assessment Data to Characterize Individual Mobility: Exploratory Pilot Study in Rural Uganda

The mostly rural district of Rakai, Uganda, is characterized by substantial mobility for fishing and trading, among other family and school-related reasons [5-7], demonstrating significant time spent away from home.

Aleya Khalifa, Laura K Beres, Aggrey Anok, Ismail Mbabali, Charles Katabalwa, Jeremiah Mulamba, Alvin G Thomas, Eva Bugos, Gertrude Nakigozi, Larry W Chang, M Kate Grabowski

JMIR Form Res 2024;8:e54207

An mHealth Intervention to Address Depression and Improve Antiretroviral Therapy Adherence Among Youths Living With HIV in Uganda: Protocol for a Pilot Randomized Controlled Trial

An mHealth Intervention to Address Depression and Improve Antiretroviral Therapy Adherence Among Youths Living With HIV in Uganda: Protocol for a Pilot Randomized Controlled Trial

A mobile health (m Health) intervention is a feasible approach for the delivery of interventions to youths with depression living with HIV in Uganda. Upwards of 85% of countries in SSA have accomplished a high level of mobile phone penetration [46]. According to the 2021 Uganda Communications Commission Report, over 70% of Ugandans own a mobile phone [47].

Proscovia Nabunya, Patricia Cavazos-Rehg, James Mugisha, Erin Kasson, Olive Imelda Namuyaba, Claire Najjuuko, Edward Nsubuga, Lindsey M Filiatreau, Abel Mwebembezi, Fred M Ssewamala

JMIR Res Protoc 2024;13:e54635

Mobile Phone Technology for Preventing HIV and Related Youth Health Problems, Sexual Health, Mental Health, and Substance Use Problems in Southwest Uganda (Youth Health SMS): Protocol for a Pilot Randomized Controlled Trial

Mobile Phone Technology for Preventing HIV and Related Youth Health Problems, Sexual Health, Mental Health, and Substance Use Problems in Southwest Uganda (Youth Health SMS): Protocol for a Pilot Randomized Controlled Trial

Further, in part owing to the lack of access to information and services related to mobility, the uptake of antiretroviral therapy among adolescents and young adults in Uganda living with HIV is considerably lower than that among adults in Uganda living with HIV [8-10]. Mental health and substance use affect decisions regarding sexual and reproductive health (SRH) and can increase the risk for acquiring HIV infection [11-13].

Philip Kreniske, Olive Imelda Namuyaba, Robert Kasumba, Phionah Namatovu, Fred Ssewamala, Gina Wingood, Ying Wei, Michele L Ybarra, Charlotte Oloya, Costella Tindyebwa, Christina Ntulo, Vincent Mujune, Larry W Chang, Claude A Mellins, John S Santelli

JMIR Res Protoc 2023;12:e49352