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Thus, validating the pooling assay and instrumentation is critical to reducing false-negative results [19-21]. In any case, using pooling as a screening technique rather than as a diagnostic method minimizes its shortcomings [9]. The Centers for Disease Control and Prevention (CDC) Interim Guidance [22] establishes the differences between diagnostic, screening, and surveillance testing and the specific requirements for each pooling application.
JMIR Public Health Surveill 2024;10:e54503
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