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Glucagon-Like Peptide-1 Receptor Agonists Combined With Personalized Digital Health Care for the Treatment of Metabolic Syndrome in Adults With Obesity: Retrospective Observational Study

Glucagon-Like Peptide-1 Receptor Agonists Combined With Personalized Digital Health Care for the Treatment of Metabolic Syndrome in Adults With Obesity: Retrospective Observational Study

This study encompassed 51 adult patients from diverse ethnic backgrounds who had completed a 6-month program duration with all Met S parameters collected. Medication administration followed a thorough assessment, including a 15-day evaluation period and initial dietary analysis, to confirm participant eligibility. Treatment selection, whether semaglutide or tirezepatide, was determined by physicians based on clinical suitability.

Hala Zakaria, Hadoun Jabri, Sheikha Alshehhi, Milena Caccelli, Joelle Debs, Yousef Said, Joudy Kattan, Noah Almarzooqi, Ali Hashemi, Ihsan Almarzooqi

Interact J Med Res 2025;14:e63079

Mobile App-Based Interactive Care Plan for Migraine: Survey Study of Usability and Improvement Opportunities

Mobile App-Based Interactive Care Plan for Migraine: Survey Study of Usability and Improvement Opportunities

The MICP was designed to facilitate remote monitoring of adult patients with migraine, deliver educational content, and streamline care delivery.

Nathan P Young, Jennifer I Stern, Stephanie J Steel, Jon O Ebbert

JMIR Form Res 2025;9:e66763

Impact on Patient Outcomes of Continuous Vital Sign Monitoring on Medical Wards: Propensity-Matched Analysis

Impact on Patient Outcomes of Continuous Vital Sign Monitoring on Medical Wards: Propensity-Matched Analysis

We first identified adult patients (aged ≥18 years) admitted to a tertiary care center (Atrium Health Wake Forest Baptist Medical Center main campus) over 2 years (between January 1, 2018, and December 31, 2019) under a primary medical service. Primary medical services included hospitalist, general internal medicine, and family medicine. Provider staffing varied by service but included physician attendings, advanced practice providers, and medical residents.

Bradley Rowland, Amit Saha, Vida Motamedi, Richa Bundy, Scott Winsor, Daniel McNavish, William Lippert, Ashish K Khanna

J Med Internet Res 2025;27:e66347

Data Interoperability in COVID-19 Vaccine Trials: Methodological Approach in the VACCELERATE Project

Data Interoperability in COVID-19 Vaccine Trials: Methodological Approach in the VACCELERATE Project

In step 3, the outcomes derived from the adult trial protocols were compared against the VACCELERATE adult master protocol (Figure 1). This comparison focused on 4 core areas of the master protocol template’s core outcome set (COS): (1) immunogenicity, (2) safety, (3) efficacy/clinical/physiological, and (4) other outcomes of interest. Differences and similarities among the protocols were identified manually. Methodology for the identification of the interoperable data points.

Salma Malik, Zoi Pana Dorothea, Christos D Argyropoulos, Sophia Themistocleous, Alan J Macken, Olena Valdenmaiier, Frank Scheckenbach, Elena Bardach, Andrea Pfeiffer, Katherine Loens, Jordi Cano Ochando, Oliver A Cornely, Jacques Demotes-Mainard, Sergio Contrino, Gerd Felder

JMIR Med Inform 2025;13:e65590

Future Patient—Telerehabilitation of Patients With Atrial Fibrillation: Protocol for a Multicenter, Mixed Methods, Randomized Controlled Trial

Future Patient—Telerehabilitation of Patients With Atrial Fibrillation: Protocol for a Multicenter, Mixed Methods, Randomized Controlled Trial

Atrial fibrillation (AF) is a chronic cardiovascular condition occurring in 3% of the adult population, the prevalence of which is predicted to more than double over the next 20 years [1]. The increase in AF prevalence may be attributed to better opportunistic screening for silent AF, aging of the population, and an increase in conditions predisposing to AF, such as obesity, hypertension, diabetes, obstructive sleep apnea, and physical inactivity [2].

Birthe Dinesen, Andi Eie Albertsen, Elisabet Dortea Ragnvaldsdóttir Joensen, Helle Spindler, Katja Møller Jensen, Kristian Kidholm, Lars Frost, Lars Dittman, Mathushan Gunasegaram, Søren Paaske Johnsen, Mads Rovsing Jochumsen, Dorthe Svenstrup

JMIR Res Protoc 2025;14:e64259

Adapting a Mobile Health App for Smoking Cessation in Black Adults With Anxiety Through an Analysis of the Mobile Anxiety Sensitivity Program Proof-of-Concept Trial: Qualitative Study

Adapting a Mobile Health App for Smoking Cessation in Black Adults With Anxiety Through an Analysis of the Mobile Anxiety Sensitivity Program Proof-of-Concept Trial: Qualitative Study

Reference 1: Disparities in adult cigarette smoking-United States, 2002-2005 and 2010-2013 Reference 15: Anxiety sensitivity in relation to quit day dropout among adult daily smokers recruited Reference 20: Identification of anxiety sensitivity classes and clinical cut-scores in a sample of adultadult

Marshall K Cheney, Adam C Alexander, Lorra Garey, Matthew W Gallagher, Emily T Hébert, Anka A Vujanovic, Krista M Kezbers, Cameron T Matoska, Michael J Zvolensky, Michael S Businelle

JMIR Form Res 2025;9:e53566