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This study aims to outline the design, implementation, and deployment of a modular data transformation pipeline that transforms oncological RWD into an HL7 FHIR format and then into a tabular format in preparation for a federated analysis (FA) across the 6 BZKF university hospitals.
J Med Internet Res 2025;27:e65681
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The creation of a trauma-informed codevelopment space was crucial to facilitate safer and more open discussions. To accomplish this, we established a parallel, intervention refinement process using a helical structure developed by this team and based on our prior research with structural indicators for community-based participatory action research [33]. As shown in Figure 2, the “hand off” of work drives an iterative (helical) thinking process.
JMIR Res Protoc 2025;14:e69829
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A total of 12 additional self-generated items were used to assess acceptability (Multimedia Appendix 2 provides the items). Except for 2 items, they were all rated on a 4-point Likert scale from 1 (not at all) to 4 (very). One item asking whether participants would recommend the training to a friend was answered with yes or no. Another item asking whether the training takes a reasonable amount of time was rated on a 5-point Likert scale from 1 (far too high) to 5 (far too low).
JMIR Form Res 2025;9:e65357
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The index visit was defined as the first order of a culprit medication for a given patient on a given hospitalization (encounter), with only one medication used to define each hospitalization for each patient. As such, a given individual patient could be included more than once, although each encounter (hospitalization) was only used once for each patient under a given culprit medication. The earliest date of enrollment was July 6, 2011, and the latest was April 16, 2024.
J Med Internet Res 2025;27:e68256
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The International Organization for Standardization describes usability as “the extent to which a system, product or service can be used by specified users to achieve specified goals with effectiveness, efficiency and satisfaction in a specified context of use” [1]. Usability testing is a method in which a product is evaluated by users as they perform tasks, and may include formative or summative testing [2].
JMIR Res Protoc 2025;14:e64350
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To enhance recruitment, a home testing option is provided, allowing families to conveniently perform finger-prick testing and data collection at home.
After screening results are available, a research physician reviews the findings. Participants who test positive for islet autoantibodies are invited to a follow-up visit that includes personalized counseling, targeted educational interventions, and additional metabolic staging to determine their T1 D stage.
JMIR Res Protoc 2025;14:e70575
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Conditional inference trees model the nonlinear relationships between a wide range of predictors and an outcome. As a data mining approach, the conditional inference tree is a data-driven analytic strategy that identifies interacting social determinants from many candidate predictors to determine which predictors are most relevant to specific outcomes.
J Med Internet Res 2025;27:e65452
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For example, medical students completing an online module on a basic science topic may be confident in their ability to learn but struggle to see the value in the material beyond their next examination. Conversely, students completing a virtual examination with a standardized patient may see the value in what they are learning but not feel confident in their ability to succeed.
JMIR Med Educ 2025;11:e64179
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Participants (N=11; mean age 43.6, SD 17.8; range 19‐76 years) were female (55%, n=6), White (91%, n=10), Hispanic (73%, n=8), with a history of acute myeloid leukemia (100%, n=11), and a mean time of 1.64 (SD 0.81) years post-SCT at the time of the focus groups.
JMIR Form Res 2025;9:e65188
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The aim of this study is to develop risk calculators that best predict (1) a mother’s risk of having a neonate with abnormal fetal growth (large for gestational age [LGA] or small for gestational age [SGA]); (2) a mother’s risk of having a serious adverse neonatal outcome; and (3) a mother’s risk of developing new metabolic disease after pregnancy (Figure 1).
JMIR Res Protoc 2025;14:e72542
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