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Alternative methods, such as K-means, Gaussian mixture models [40], and density-based spatial clustering of applications with noise (DBSCAN) [41], face theoretical limitations: K-means assumes spherical clusters that is difficult to satisfy in high-dimensional embeddings; DBSCAN relies on density thresholds that break down in such spaces; and Gaussian mixture models can be unstable with overlapping subtypes.
JMIR Aging 2025;8:e65178
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