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Assessing the Noninferiority of a Rhythm and Language Training Serious Game Combined With Speech Therapy Versus Speech Therapy Care for Children With Dyslexia: Protocol for an Investigator-Blinded Randomized Controlled Trial

Assessing the Noninferiority of a Rhythm and Language Training Serious Game Combined With Speech Therapy Versus Speech Therapy Care for Children With Dyslexia: Protocol for an Investigator-Blinded Randomized Controlled Trial

The maximum acceptable inferiority for experimental versus control on the primary outcome is therefore expected to be a standardized difference (Cohen d=0.39), which corresponds to a label between small or medium, depending on the guidelines (R effect size package) [44]. Considering a one-sided significance level of 2.5% and a power of 90%, it is necessary to include 137 participants per group (G*Power 3.1).

Charline Grossard, Mélanie Descamps, Sara Cadoni, Hugues Pellerin, François Vonthron, Jean Xavier, Bruno Falissard, David Cohen

JMIR Res Protoc 2025;14:e71326

Multilevel Intervention to Increase Patient Portal Use in Adults With Type 2 Diabetes Who Access Health Care at Community Health Centers: Single Arm, Pre-Post Pilot Study

Multilevel Intervention to Increase Patient Portal Use in Adults With Type 2 Diabetes Who Access Health Care at Community Health Centers: Single Arm, Pre-Post Pilot Study

We estimated the Cohen d effect size of MAP on A1 C and tested the statistical significance of the change from baseline using longitudinal models, including generalized linear mixed model (GLMM), a logistic model with random intercept (which incorporates the correlation within repeated measures), and a negative binomial model with random intercept. The coefficients of the categorial time variable (ie, baseline, 3 months, and 6 months) represent the average change of Hb A1c at 3 and 6 months from baseline.

Robin Whittemore, Sangchoon Jeon, Samuel Akyirem, Helen N C Chen, Joanna Lipson, Maritza Minchala, Julie Wagner

JMIR Form Res 2025;9:e67293

GPT-4 as a Clinical Decision Support Tool in Ischemic Stroke Management: Evaluation Study

GPT-4 as a Clinical Decision Support Tool in Ischemic Stroke Management: Evaluation Study

Agreement between treatment decisions was measured using a linear weighted Cohen κ coefficient, using the psych 2.3.12 library. This study was approved by the Rambam Medical Center Helsinki Committee (0156-24-D) as a retrospective analysis. The requirement for informed consent was waived due to the retrospective nature of the study and the use of deidentified data. All patient information was anonymized prior to analysis, with all identifiers, names, and dates removed to ensure privacy and confidentiality.

Amit Haim Shmilovitch, Mark Katson, Michal Cohen-Shelly, Shlomi Peretz, Dvir Aran, Shahar Shelly

JMIR AI 2025;4:e60391