TY - JOUR AU - Mehta, Mihir AU - Julaiti, Juxihong AU - Griffin, Paul AU - Kumara, Soundar PY - 2020 DA - 2020/9/11 TI - Early Stage Machine Learning–Based Prediction of US County Vulnerability to the COVID-19 Pandemic: Machine Learning Approach JO - JMIR Public Health Surveill SP - e19446 VL - 6 IS - 3 KW - COVID-19 KW - coronavirus KW - prediction model KW - county-level vulnerability KW - machine learning KW - XGBoost AB - Background: The rapid spread of COVID-19 means that government and health services providers have little time to plan and design effective response policies. It is therefore important to quickly provide accurate predictions of how vulnerable geographic regions such as counties are to the spread of this virus. Objective: The aim of this study is to develop county-level prediction around near future disease movement for COVID-19 occurrences using publicly available data. Methods: We estimated county-level COVID-19 occurrences for the period March 14 to 31, 2020, based on data fused from multiple publicly available sources inclusive of health statistics, demographics, and geographical features. We developed a three-stage model using XGBoost, a machine learning algorithm, to quantify the probability of COVID-19 occurrence and estimate the number of potential occurrences for unaffected counties. Finally, these results were combined to predict the county-level risk. This risk was then used as an estimated after-five-day-vulnerability of the county. Results: The model predictions showed a sensitivity over 71% and specificity over 94% for models built using data from March 14 to 31, 2020. We found that population, population density, percentage of people aged >70 years, and prevalence of comorbidities play an important role in predicting COVID-19 occurrences. We observed a positive association at the county level between urbanicity and vulnerability to COVID-19. Conclusions: The developed model can be used for identification of vulnerable counties and potential data discrepancies. Limited testing facilities and delayed results introduce significant variation in reported cases, which produces a bias in the model. SN - 2369-2960 UR - http://publichealth.jmir.org/2020/3/e19446/ UR - https://doi.org/10.2196/19446 UR - http://www.ncbi.nlm.nih.gov/pubmed/32784193 DO - 10.2196/19446 ID - info:doi/10.2196/19446 ER -