%0 Journal Article
%@ 2369-2960
%I JMIR Publications
%V 9
%N 
%P e43381
%T Disease Burden and the Accumulation of Multimorbidity of Noncommunicable Diseases in a Rural Population in Henan, China: Cross-sectional Study
%A Chen,Ying
%A Pan,Mingming
%A He,Yaling
%A Dong,Xiaokang
%A Hu,Ze
%A Hou,Jian
%A Bao,Yining
%A Yang,Jing
%A Yuchi,Yinghao
%A Li,Ruiying
%A Zhu,Linghui
%A Kang,Ning
%A Liao,Wei
%A Li,Shuoyi
%A Wang,Chongjian
%A Zhang,Lei
%+ China-Australia Joint Research Center for Infectious Diseases, School of Public Health, Xi’an Jiaotong University Health Science Center, No. 76, Yanta West Road, Xi’an, Shaanxi, 710061, China, 86 29 82655135, lei.zhang1@monash.edu
%K multimorbidity
%K prevalence
%K associating factors
%K noncommunicable disease accumulation
%K NCD accumulation
%K public health
%D 2023
%7 22.5.2023
%9 Original Paper
%J JMIR Public Health Surveill
%G English
%X Background: Multimorbidity causes substantial disease and economic burdens on individuals and the health care system. Objective: This study aimed to explore the disease burden of multimorbidity and the potential correlations among chronic noncommunicable diseases (NCDs) in a rural population in Henan, China. Methods: A cross-sectional analysis was performed using the baseline survey of the Henan Rural Cohort Study. Multimorbidity was defined as the simultaneous occurrence of at least two NCDs in a participant. This study examined the multimorbidity pattern of 6 NCDs, including hypertension, dyslipidemia, type 2 diabetes mellitus, coronary heart disease, stroke, and hyperuricemia. Results: From July 2015 to September 2017, a total of 38,807 participants (aged 18-79 years; 15,354 men and 23,453 women) were included in this study. The overall population prevalence of multimorbidity was 28.1% (10,899/38,807), and the multimorbidity of hypertension and dyslipidemia was the most common (8.1%, 3153/38,807). Aging, higher BMI, and unfavorable lifestyles were significantly associated with a higher risk of multimorbidity (multinomial logistic regression, all P<.05). The analysis of the mean age at diagnosis suggested a cascade of interrelated NCDs and their accumulation over time. Compared with participants without 2 conditional NCDs, participants with 1 conditional NCD would have higher odds of another NCD (1.2-2.5; all P<.05), and those with 2 conditional NCDs would elevate the odds of the third NCD to 1.4-3.5 (binary logistic regression, all P<.05). Conclusions: Our findings indicate a plausible tendency for the coexistence and accumulation of NCDs in a rural population in Henan, China. Early prevention of multimorbidity is essential to reduce the NCD burden in the rural population. 
%M 37213192
%R 10.2196/43381
%U https://publichealth.jmir.org/2023/1/e43381
%U https://doi.org/10.2196/43381
%U http://www.ncbi.nlm.nih.gov/pubmed/37213192