%0 Journal Article
%@ 2369-2960
%I JMIR Publications
%V 8
%N 6
%P e33995
%T Reasons for COVID-19 Vaccine Hesitancy Among Chinese People Living With HIV/AIDS: Structural Equation Modeling Analysis
%A Yao,Yan
%A Chai,Ruiyu
%A Yang,Jianzhou
%A Zhang,Xiangjun
%A Huang,Xiaojie
%A Yu,Maohe
%A Fu,Geng-feng
%A Lan,Guanghua
%A Qiao,Ying
%A Zhou,Qidi
%A Li,Shuyue
%A Xu,Junjie
%+ Clinical Research Academy, Peking University Shenzhen Hospital, Peking University, 1120, Lianhua Road, Futian District, Shenzhen, 518036, China, 86 755 8392333, xjjcmu@163.com
%K COVID-19 vaccine
%K vaccine hesitancy
%K PLWHA
%K structural equation modeling
%D 2022
%7 30.6.2022
%9 Original Paper
%J JMIR Public Health Surveill
%G English
%X Background: Many countries and organizations recommended people living with HIV/AIDS (PLWHA) receive the COVID-19 vaccine. However, vaccine hesitancy still exists and becomes a barrier for promoting COVID-19 vaccination among PLWHA. Objective: This study aims to investigate factors that contributed to COVID-19 vaccine hesitancy among PLWHA. Methods: The study used a multicenter cross-sectional design and an online survey mode. We recruited PLWHA aged 18-65 years from 5 metropolitan cities in China between January 2021 and February 2021. Participants completed an online survey through Golden Data, a widely used encrypted web-based survey platform. Multiple linear regression models were used to assess the background characteristics in relation to COVID-19 vaccine hesitancy, and structural equation modeling was performed to assess the relationships among perceived benefits, perceived risks, self-efficacy, subjective norms, and COVID-19 vaccine hesitancy. Results: Among 1735 participants, 41.61% (722/1735) reported COVID-19 vaccine hesitancy. Older age, no other vaccinations in the past 3 years, and having chronic disease history were positively associated with COVID-19 vaccine hesitancy. Structural equation modeling revealed a direct relationship of perceived benefits, perceived risks, and subjective norms with self-efficacy and vaccine hesitancy and an indirect relationship of perceived benefits, perceived risks, and subjective norms with vaccine hesitancy. Moreover, self-efficacy toward COVID-19 vaccination was low. PLWHA had concerns of HIV disclosure during COVID-19 vaccination. Family member support could have an impact on COVID-19 vaccination decision-making. Conclusions: COVID-19 vaccine hesitancy was high among PLWHA in China. To reduce COVID-19 vaccine hesitancy, programs and strategies should be adopted to eliminate the concerns for COVID-19 vaccination, disseminate accurate information on the safety and efficacy of the COVID-19 vaccine, encourage family member support for COVID-19 vaccination, and improve PLWHA’s trust of medical professionals. 
%M 35486810
%R 10.2196/33995
%U https://publichealth.jmir.org/2022/6/e33995
%U https://doi.org/10.2196/33995
%U http://www.ncbi.nlm.nih.gov/pubmed/35486810