@Article{info:doi/10.2196/33995,
author="Yao, Yan
and Chai, Ruiyu
and Yang, Jianzhou
and Zhang, Xiangjun
and Huang, Xiaojie
and Yu, Maohe
and Fu, Geng-feng
and Lan, Guanghua
and Qiao, Ying
and Zhou, Qidi
and Li, Shuyue
and Xu, Junjie",
title="Reasons for COVID-19 Vaccine Hesitancy Among Chinese People Living With HIV/AIDS: Structural Equation Modeling Analysis",
journal="JMIR Public Health Surveill",
year="2022",
month="Jun",
day="30",
volume="8",
number="6",
pages="e33995",
keywords="COVID-19 vaccine; vaccine hesitancy; PLWHA; structural equation modeling",
abstract="Background: Many countries and organizations recommended people living with HIV/AIDS (PLWHA) receive the COVID-19 vaccine. However, vaccine hesitancy still exists and becomes a barrier for promoting COVID-19 vaccination among PLWHA. Objective: This study aims to investigate factors that contributed to COVID-19 vaccine hesitancy among PLWHA. Methods: The study used a multicenter cross-sectional design and an online survey mode. We recruited PLWHA aged 18-65 years from 5 metropolitan cities in China between January 2021 and February 2021. Participants completed an online survey through Golden Data, a widely used encrypted web-based survey platform. Multiple linear regression models were used to assess the background characteristics in relation to COVID-19 vaccine hesitancy, and structural equation modeling was performed to assess the relationships among perceived benefits, perceived risks, self-efficacy, subjective norms, and COVID-19 vaccine hesitancy. Results: Among 1735 participants, 41.61{\%} (722/1735) reported COVID-19 vaccine hesitancy. Older age, no other vaccinations in the past 3 years, and having chronic disease history were positively associated with COVID-19 vaccine hesitancy. Structural equation modeling revealed a direct relationship of perceived benefits, perceived risks, and subjective norms with self-efficacy and vaccine hesitancy and an indirect relationship of perceived benefits, perceived risks, and subjective norms with vaccine hesitancy. Moreover, self-efficacy toward COVID-19 vaccination was low. PLWHA had concerns of HIV disclosure during COVID-19 vaccination. Family member support could have an impact on COVID-19 vaccination decision-making. Conclusions: COVID-19 vaccine hesitancy was high among PLWHA in China. To reduce COVID-19 vaccine hesitancy, programs and strategies should be adopted to eliminate the concerns for COVID-19 vaccination, disseminate accurate information on the safety and efficacy of the COVID-19 vaccine, encourage family member support for COVID-19 vaccination, and improve PLWHA's trust of medical professionals. ",
issn="2369-2960",
doi="10.2196/33995",
url="https://publichealth.jmir.org/2022/6/e33995",
url="https://doi.org/10.2196/33995",
url="http://www.ncbi.nlm.nih.gov/pubmed/35486810"
}