Cancer has become a significant global public health concern, surpassing cardiovascular diseases as the leading cause of death in many high-income countries [1]. Breast cancer (BC) is the most diagnosed, with around 2.3 million new cases and 670,000 deaths in 2022 [2-4], making it the leading cause of cancer-related death among women globally [3,4]. Although the incidence of BC is lower in high-income countries, it is often diagnosed at advanced stages, leading to higher mortality rates [5].

As a low-income country, the World Bank classifies Jordan as a lower-middle-income country (LMIC) [6]. It confronts substantial health care resource management challenges, particularly for noncommunicable diseases like cancer [5,7]. BC is the most common cancer among women in Jordan, accounting for 39.2% of female cancer cases in 2022. The age-standardized rate (ASR) of BC is 60 per 100,000 population, which is higher than in some neighboring Arab countries but lower than in Western countries. The global ASR average is 46.8 [2,8,9]. The rising incidence of BC in LMICs is linked to increased life expectancy, improved health care services, and increased health insurance coverage. In addition, the adoption of Western lifestyles and changes in reproductive behaviors, such as delayed childbirth and shorter breastfeeding durations, have also contributed to this trend [10,11].

The American College of Radiology (ACR) recommends that all women at average risk of BC should begin annual mammograms at the age of 40 years. Moreover, women who are at higher-than-average risk due to various factors are recommended to undergo more intensive screening [12]. Ultimately, mammography screening can reduce BC mortality by 40% or more in women aged 40 years and older [12]. Early detection of BC through mammography can lead to significantly improved survival rates [12,13]. In response to this, Jordan established the Jordan Cancer Registry in 1996, the King Hussein Cancer Foundation and Center in 2001, and the Jordan Breast Cancer Program (JBCP) in 2007 to coordinate detection efforts, provide screening, and raise public awareness [11]. It also recommends that women begin mammogram screenings at the age of 40 years [9,14].

Despite these national initiatives, participation in mammography screening remains low. According to the Jordan Cancer Registry, only 18.6% of women aged 40-69 years have undergone mammographic screening in the past 2 years [15]. Another survey indicated that just 14% of women aged 40-49 years have ever had a mammogram [16]. These rates are comparable to those in neighboring countries, such as Qatar (22.5%) and Saudi Arabia (27.7%) [17,18]. However, they are still significantly lower than the rates reported in high-income countries, such as France (48.5%) and the United States (61%) [19,20]. This low participation persists despite the expansion of screening services and public awareness campaigns, indicating ongoing barriers to preventive care [7,11,14].

One of the main challenges and barriers is that many Jordanian women are unaware of their eligibility for screening due to a lack of awareness, absence of health problems, fear of diagnosis, and the influence of cultural and religious beliefs [16,21]. Although educational interventions have been implemented, evidence suggests that simply increasing awareness is insufficient to effect meaningful change in screening behaviors [21-23]. Deeply rooted beliefs and attitudes, shaped by cultural and individual factors, continue to hinder adherence to breast cancer screening (BCS) guidelines [24,25]. Furthermore, health beliefs regarding mammography among this age group in Jordan are underresearched [26,27].

To address these gaps, this study aims to investigate how knowledge and health beliefs about mammography screening practices based on the Health Belief Model (HBM) among Jordanian women aged 40 years and older. The study also seeks to identify the sociodemographic characteristics that influence knowledge and beliefs regarding screening.

This study is guided by the HBM, a theoretical framework that explains preventive health behaviors in various contexts, such as vaccination and smoking [28,29]. The HBM suggests that individuals’ actions are influenced by their perceptions of susceptibility, severity, benefits, barriers, cues for action, and self-efficacy [28-30].

Victoria Champion developed the Champion Health Belief Model (CHBM) as an adaptation of the original HBM to better understand and predict women’s participation in BCS behaviors [31,32]. Champion initially created separate scales to measure constructs such as perceived susceptibility, benefits, and barriers related to BCS [31,32]. These scales were later combined and revised to form the Champion Health Belief Model Scale (CHBMS) [33,34]. This comprehensive instrument emphasizes health motivation and self-efficacy in women’s decisions to participate in BCS, while also taking into account cultural factors [33,34]. The CHBMS has been adapted and validated in various cultural contexts to assess the beliefs and attitudes that influence BCS behaviors [22,26,34,35].

In this study, we used 3 constructs of the CHBMS: perceived benefits, barriers, and health motivation. These constructs were selected based on the study conducted by Petro-Nustas [26], who revised these specific aspects of the CHBMS [22,33]. This psychometrically validated tool has been used to assess the beliefs of Jordanian women regarding mammography.

This study implemented a cross-sectional design to assess the knowledge and beliefs about BC and mammography among Jordanian women aged 40 years and older. It adhered to the Strengthening of the Reporting of Observational Studies in Epidemiology (STROBE) guidelines (Checklist 1) [36]. The HBM served as the theoretical framework for this study, as it has been identified as the most frequently used and suitable theoretical health behavior model in previous studies that explain women’s BCS practices [37,38].

This study was conducted at Albashir Hospital in Amman, Jordan, the largest public medical complex in the country. It is a national referral center comprising multiple specialized hospitals and centers. The sample included women from different socioeconomic and clinical backgrounds. In 2022, the hospital’s outpatient clinics received a total of 632,352 patients who visited the hospital and the outpatient clinics. Participant recruitment and data collection took place from women attending various outpatient clinics between May and July 2024 during regular clinic hours (8:00 AM to 4:00 PM, Sunday through Thursday).

The variables of interest in this study—sociodemographic data, knowledge of BC, and health beliefs about mammography screening—were clearly defined and systematically measured. Data for all variables were collected using a questionnaire. The questionnaire consisted of 3 sections: sociodemographic characteristics, knowledge about BC, and health beliefs, measured using 3 constructs from the CHBMS.

The sociodemographic data section included questions about participants’ age, education, marital status, health insurance status, and mammography screening history in the past 12 months (these questions were used to assess participants’ eligibility). In addition, participants were asked an open-ended question to provide up to 4 reasons for not having a mammogram, offering qualitative insight into the barriers to screening, with no specific order required.

The knowledge section featured 12 true, false, or do not know questions about BC, with 7 correct answers marked as “true” and 5 as “false.” Participants scored 1 point for each correct answer and zero for each incorrect or “do not know” answer. The maximum possible score was 12, indicating excellent knowledge, while a score of zero indicated limited knowledge.

The health belief section consisted of 3 constructs from the CHBMS, comprising 18 statements: 6 related to perceived benefits, 5 to perceived barriers, and 7 to health motivation. The scale is positively associated with screening behaviors, except for perceived barriers, which are negatively associated. Each statement was rated on a 5-point Likert scale (1=strongly disagree to 5=strongly agree), with reversed scoring applied to the barriers. Scores ranged from 18 (highly negative beliefs) to 90 (highly positive beliefs).

In the previous section on health beliefs, we used a culturally adapted Arabic version of the CHBMS (Multimedia Appendix 1), initially translated and validated for BCS among Jordanian women by Mikhail and Petro-Nustas in 2001 [35]. Petro-Nustas later revised and validated the entire questionnaire to better reflect the health beliefs of Jordanian women regarding mammography, focusing on 3 constructs from the CHBMS: perceived benefits, perceived barriers, and health motivation [22]. Our study followed this methodology and obtained permission from Petro-Nustas and Champion to use the questionnaire (Multimedia Appendix 2).

The study size was determined based on previous relevant studies [14,24,27] 2727 and calculated using the Raosoft sample size calculator (Raosoft, Inc) [39]. The target population consisted of Jordanian women aged 40 years or older, totaling approximately 1,460,300 in 2023. Based on a 95% confidence level, a 5% margin of error, and a response distribution of 50%, the minimum required sample size was determined to be 384 participants. A total of 405 women were recruited to mitigate potential nonresponses, attrition, and data exclusion while preserving statistical power.

Descriptive statistics were calculated, including the mean and SD for continuous data and frequencies and percentages for categorical data. A Multivariate Analysis of Variance (MANOVA) was conducted to examine the association between sociodemographic independent variables: age, educational level, marital status, and health insurance, and the dependent variables: knowledge and health beliefs based on the HBM, specifically in terms of perceived benefits, perceived barriers, and health motivation. Following significant results from the MANOVA (P<.05), indicating an association between the dependent and independent variables, Bonferroni post hoc tests were conducted to determine which specific groups within each dependent variable showed statistically significant differences (P<.001); to quantify the magnitude of effects beyond statistical significance, partial eta-squared (ηp²) values were calculated for each independent and dependent variable relationship. All statistical analyses were performed using IBM SPSS version 28 [40].

This study was conducted in accordance with the ethical principles outlined in the Declaration of Helsinki. Ethical approval was obtained from the Institutional Review Board (IRB) of the Ministry of Health and Albashir Hospital in Jordan (IRB-7790) in May 2024 (Multimedia Appendix 3). Written consent was obtained from all participants before their participation (Multimedia Appendix 4). They were provided with detailed information about the study’s aims and significance, as well as their right to withdraw at any time without any obligations. To ensure privacy, no personal identifiers were used; participants were assigned unique code numbers to maintain confidentiality. No financial compensation or incentives were provided to participants.

Out of 2608 women screened at Albashir Hospital outpatient clinics, 376 were excluded, and 1827 refused to participate, resulting in 405 eligible participants who consented and completed the study. This process is outlined in the STROBE flow diagram [36] as shown in Figure 1.

A total of 405 Jordanian women participated in the study, aged 40-76 years. The vast majority, 187 (46.2%), fell within the 40‐49 years age group, 173 (42.7%) completed secondary education, 213 (52.6%) were married, 372 (91.9%) reported having health insurance, and none had undergone mammogram screening in the past 12 months (Table 1).

The participants’ responses to the open-ended questions were analyzed and categorized into 8 main reasons that may negatively impact screening practices. An example of the main reasons reported among the 405 participants was a lack of knowledge, cited by 72.8% (295). This was followed by fear of results, reported by 66.4% (269), cultural beliefs at 63% (255), and religious reasons, mentioned by 29.4% (119) (Multimedia Appendix 5).

Table 2 shows that the overall knowledge score about BC was relatively low (48.3%), with a mean (SD) score of 5.80 (2.64). Regarding knowledge aspects, approximately out of 405, three-quarters of the sample, 74.3% (301), correctly recognized that BC is the most common cancer among women. In addition, half of the sample, 206 (50.9%), identified excess weight and having a first child after age 30 years as risk factors for BC. In contrast, only 145 (35.8%) correctly identified that most breast tumors are not cancerous.

Scores for each construct and question within the CHBM scale ranged from 1 to 5. The perceived benefits of mammography had a relatively low mean (SD) score of 2.59 (0.59). Among the perceived benefits, women identified that mammography helps in the early detection of lumps, with a mean (SD0 score of 2.62 (1.08). The perception that mammography decreases the chances of dying from BC had a mean (SD0 score of 2.60 (1.13). Furthermore, the item related to reducing worry about BC was rated the lowest, with a mean (SD) score of 2.45 (1.19) (Table 3).

The perceived barriers to undergoing mammograms were assessed with a mean (SD) score of 2.48 (0.71), indicating that women have various concerns about this procedure. Worries related to BC (item 7) had a mean (SD) score of 2.52 (0.92), while fears of pain had a mean (SD) score of 2.48 (1.02). Item 8, “Having a mammogram of the breast would be embarrassing,” was the highest perceived barrier, with a mean (SD) score of 2.38 (1.00).

Participants reported a low health motivation score regarding mammography, with a mean (SD) of 2.51 (0.71). Among the health motivation items, the desire to detect health problems early (item 12) had the highest mean (SD) score of 2.64 (1.09). In contrast, lower scores were observed for exercising 3 times a week (item 17), with a mean (SD0 of 2.31 (0.95), and for undergoing regular health check-ups even when not sick (item 18), with a mean (SD) of 2.11 (1.08).

The statistical analysis, conducted using MANOVA, revealed that age and educational level had a significant influence on knowledge and beliefs, as measured by the CHBM scale (P<.05 for all). Moreover, the Bonferroni post hoc tests for age groups and educational levels revealed that women aged 60 years and older with primary or secondary education demonstrated lower levels of knowledge, perceived benefits, and health motivation. In addition, they reported higher perceived barriers compared with women in the 40‐49 years and 50‐59 years age groups who had a university education (P<.001). In contrast, marital status and health insurance had no significant effect on the variables related to BC and mammography (P>.05 for all) (Table 4).

The results showed that age significantly influenced knowledge (F₂₄₀₂=22.44; P<.001). Participants aged 40‐49 years had a mean (SD) score of 6.43 (2.70), while those aged 50‐59 years had a mean (SD) score of 5.86 (2.44). These groups had significantly higher mean scores than participants aged 60 years and older, who had a mean (SD) score of 4.17 (2.13, P<.001). In addition, the educational level also significantly influenced knowledge (F₂₄₀₂=179.05; P<.001). Participants with a university education had mean (SD) scores of 8.19 (2.15), which were higher than those with secondary education, 5.98 (1.92), and primary education, 3.42 (1.69), P<.001. In addition, the partial eta squared (ηp²) results for age showed a medium effect size for knowledge (ηp²=0.10), while education level displayed a large effect size for knowledge (ηp²=0.471).

Similarly, perceived benefits were significantly influenced by age (F₂₄₀₂=27.82; P<.001), and had a medium effect size (ηp²=0.122). The mean (SD) score for the participants aged 40‐49 years was 2.86 (0.97), and for those aged 50‐59 years, it was 2.54 (0.70). Both mean scores were higher than those of participants aged 60 years and older, who had a mean (SD) score of 2.02 (0.68), P<.001. In addition, the educational level significantly influenced perceived benefits (F₂₄₀₂=203.11; P<.001), and had a medium effect size (ηp²=0.503). Participants with a university education had higher mean (SD) scores of 3.44 (0.81) compared with those with secondary education, 2.63 (0.60), and primary education, 1.77 (0.47), P<.001.

Moreover, the perceived barriers were significantly influenced by age (F₂₄₀₂=19.32; P<.001) with a medium effect size (ηp²=0.088). Participants aged 60 years and older displayed significantly higher barrier scores, with a mean (SD) score of 2.08 (0.64), compared with those in the 40‐49 years age group, 2.65 (0.73), and the 50‐59 years age group, 2.48 (0.63), P<.001. In addition, the educational level had a significant influence (F₂₄₀₂=45.24; P<.001), and a large effect size (ηp²=0.184). Participants with primary education had higher barrier mean (SD) scores of 2.09 (0.66) compared to those with secondary education, 2.50 (0.60), and university education, 2.89 (0.69), P<.001.

Ultimately, health motivation was significantly influenced by age (F₂₄₀₂=17.53; P<.001). The participants’ mean (SD) score for both ages 40‐49 years was 2.68 (0.77), and that for 50‐59 years was 2.49 (0.62), which was higher than those of participants 60 years and older, 2.14 (0.57), P<.001. The educational level also had a significant influence (F₂₄₀₂=118.54; P<.001), with women holding a university education 3.08 (0.64) scoring higher than those with secondary education 2.56 (0.58) and primary education 1.94 (0.47), P<.001. Furthermore, the partial eta squared results for age revealed a medium effect size for health motivation (ηp²=0.080). The effect size was large for both educational level and health motivation (ηp²=0.371).

Regarding marital status, the effect sizes were small or negligible for all dependent variables: knowledge (ηp²=0.019), perceived benefits (ηp²=0.005), perceived barriers (ηp²=0.007), and health motivation (ηp²=0.003). Finally, there was no effect (ηp²=0.000) on any dependent variables for health insurance status.

This cross-sectional study examines the knowledge and beliefs of Jordanian women aged 40 years and older regarding BC and mammography, using the HBM as a theoretical framework. The findings offer valuable insights into the knowledge, perceived benefits, barriers, and health motivations that influence mammogram screening practices among this population.

Participants in this study reported several barriers that adversely affected their participation in screening practices, such as cost, fear of results, pain, cultural beliefs, and religious factors. These findings were consistent with those observed by Abu-Helalah et al in Jordan [14], which identified the main reasons for avoiding screening as fear of results (63.8%), lack of support (59.7%), cost (53.4%), and religious beliefs (51.1%). Another study conducted by AlAbdulKader et al [41] in Saudi Arabia found that the main barriers to receiving BCS include feeling that it is unnecessary (24.2%), believing it to be painful (22.1%), and fearing abnormal results (18.6%). In addition, other regional and global studies support these findings, highlighting fear of pain and fear of diagnosis as common reasons for avoiding BCS [42,43].

Furthermore, the prevalence of cultural beliefs (63%) and religious factors (29.4%) is a significant barrier to mammography screening, as observed in our study and supported by Albadawi et al [44], who found that these beliefs influence BCS behaviors among women in Jordan. Similarly, Taha et al [45] and Salman et al [46] revealed through qualitative interviews that many Jordanian women hold fatalistic views shaped by the religious concept of “Qadaa Wa Qadar” (predestination).

These beliefs lead many to view BC as “from Allah (God)” and thus unavoidable, reducing their perceived benefits of early detection. This religious fatalism, as highlighted in studies by Petro-Nustas et al and Donnelly et al [22,47], serves as a significant barrier to adopting preventive health behaviors. Moreover, Taha et al [45] also discussed this in a study conducted in Jordan, where men viewed BC as an unavoidable act of God, detached from their families. This belief is linked to notions of improper behavior and a readiness to confront the cultural stigma of Eib (shame) [48]. In addition, research by Al-Naggar and Bobryshev [49] found that religious beliefs accounted for 42.5% of screening avoidance among Malaysian Muslim women, closely aligning with our finding of 37.5%. Their study also emphasized that support from religious leaders can boost participation rates, a factor worth exploring in the Jordanian context.

We observed a significant lack of knowledge about BC among the participants in this study, with a low average score of 5.80 out of 12. Furthermore, 72.8% of participants indicated that their lack of knowledge was the primary reason for not undergoing mammogram screenings. This finding aligns with Kawar’s study [50], which emphasized the importance of health care advice in improving awareness and encouraging participation in screenings. In addition, a 2023 national survey conducted among Palestinian women revealed that 53.2% believed the idea of “having a physical trauma” was a myth associated with BC, while 19.4% regarded “wearing a tight bra” as a misconception [51]. In contrast, our study found that only 43.5% of participants understood that not all fibrous sacs increase the risk of BC, and only 35.8% recognized that not all breast tumors are cancerous. These findings suggest a substantial gap in understanding breast abnormalities, which is similar to the health literacy deficiencies commonly observed in low-resource settings, where limited access to accurate health information contributes to poor health literacy [7,52,53].

The findings from the CHBM scale in this study revealed that perceived barriers had the lowest mean (SD) score of 2.48 (0.71) out of 5, followed by health motivation at 2.51 (0.59) out of 5 and perceived benefits at 2.59 (0.71) out of 5. This finding is consistent with previous studies that have identified perceived barriers as the most significant predictor of mammogram screening [27,33,37]. Participants in our study showed a negative perception regarding the benefits of mammography, as evidenced by their lower scores on statements such as: “When I get a mammogram, I do not worry as much about BC” and “Having a mammogram will decrease my chances of dying from BC.” These results were compatible with findings from other studies [22,33], as reported by Al-Naggar and Bobryshev [49], which indicated that Malaysian women with a limited understanding of the benefits of mammography were less likely to participate in regular screenings; only 15% had ever undergone a mammogram. Together, these findings underscore the importance of educational interventions in addressing misconceptions and promoting awareness of the benefits of mammography [54].

In our study, participants reported higher perceived barriers to mammogram screening, such as the belief that “having a mammogram would be embarrassing” or “having a mammogram would be painful.” Previous studies support these findings, as Amin et al [55] found that embarrassment and anxiety about pain significantly deterred Bangladeshi women from mammography screening, especially where modesty is prioritized. In addition, Al-Mousa et al [56] found that Jordanian women often avoid mammography due to feelings of embarrassment and fear of the results, as they believe they do not need a mammogram if they have no family history of BC, which is deeply rooted in cultural beliefs. These studies emphasize the need for culturally sensitive interventions to increase the screening rate.

Moreover, participants in our study had a negative perception of health motivation, with low mean scores for attending regular check-ups, maintaining a balanced diet, and exercising regularly. These findings suggest that targeted health interventions should increase awareness about the importance of routine check-ups, provide accessible and culturally appropriate dietary guidance, and promote exercise through structured programs to foster sustained engagement in preventive health behaviors [22,23,56]. The motivation for health and awareness was significantly associated with screening behavior [27].

Our study’s findings, related to the association between sociodemographic characteristics and knowledge and beliefs regarding BC and mammography, reveal that participants’ age and education have a significant influence on their knowledge and beliefs. Older and less educated women showed lower awareness and more negative perceptions regarding the screening. These results align with previous studies and underscore the significant influence of age and education on shaping women’s perspectives toward mammography screening [23,27,56,57].

Specifically, our study’s findings revealed a significant association between knowledge and beliefs, as measured by the CHBMS, and the ages and educational levels of the participants (P<.05). Participants aged 40‐49 years and 50‐59 years scored higher on knowledge, perceived benefits, and health motivation compared with those aged 60 years and older (P<.001). This was consistent with previous studies suggesting that younger women have better access to health information, are more exposed to BC awareness campaigns, and benefit from higher literacy rates and greater access to digital platforms [58,59]. Younger women appreciate early detection, which is influenced by targeted screening and health care recommendations. Moreover, older women may underestimate the benefits of mammography, possibly due to rooted cultural beliefs, as found by Mah et al [60] that older women felt less vulnerable to BC than younger women and were less positive about screening. This suggests that motivation declines with age due to health priorities and misconceptions about the effectiveness of screening in older adults [61,62].

Similarly, women with a university education scored higher on knowledge, perceived benefits, and health motivation compared to those with secondary and primary education (P<.001). This supports the notion that individuals with higher education are more proactive about their health and preventive care and are more likely to follow medical advice [63]. This suggests that highly educated women are more likely to recognize the value of early detection and preventive care [64]. This suggests a more substantial health motivation for the importance of screening among women with higher levels of education [63,64].

Conversely, the perceived barriers were significantly more negative among participants aged 60 years and older compared with those aged 40‐49 years and 50‐59 years (P<.001), aligning with the logistical and psychological challenges faced by older women and their traditional beliefs [65,66]. Furthermore, participants with primary education reported more barriers than those with secondary and university education (P<.001), suggesting that lower education is associated with higher perceived obstacles, such as lack of knowledge, fear, embarrassment, financial concerns, and cultural beliefs [67,68].

Neither marital status nor health insurance had a significant impact on knowledge and beliefs (P>.05). This finding contrasts with studies suggesting that married women benefit from spousal support for mammography [69,70]. While health insurance facilitates access to screening, its impact may diminish in areas with few financial barriers [71,72].

The study has several limitations. Its cross-sectional design uses convenience sampling, which prevents the determination of causal relationships between beliefs and screening behaviors and limits the generalizability of the results. The reliance on self-reported data may introduce information bias. Recruiting participants from a single hospital through convenience sampling may limit the generalizability of the findings to all Jordanian women aged 40 years and older, as it will not encompass all Jordanian women from different geographical locations, particularly those from rural areas. Furthermore, excluding women who had a mammogram within the last 12 months, as well as those with personal or family histories of BC, may introduce selection bias and limit insights into the influence of hereditary factors on screening behaviors.

Developing effective educational interventions for Jordanian women requires a multifaceted approach that addresses both individual and systemic barriers. These interventions must account for varying levels of awareness, health beliefs, and the influence of religious factors, such as fatalism, which affect screening behaviors. Involving religious and community leaders in program content can boost motivation and reduce participation barriers.

Educational initiatives should include different community activities, such as workshops, home visits, and outreach sessions with community leaders, religious figures, and BC survivors. This approach fosters trust and delivers culturally appropriate information. Expanding mobile mammography units and organizing workplace screening campaigns are crucial, especially for underserved rural populations.

Public health officials and health care providers need ongoing training in culturally competent communication and patient counseling to ensure sensitive and supportive care. To improve accessibility, financial barriers can be addressed by offering free or subsidized mammograms for low-income women and advocating for broader insurance coverage.

Delivery methods should use digital health tools, such as mobile apps and SMS text messaging reminders, which can enhance personalized education and appointment alerts. In addition, providing culturally appropriate support services, including flexible scheduling and female-only environments, is important for addressing concerns about modesty and privacy.

These interventions should be integrated within a robust policy framework that updates national screening guidelines and incorporates educational efforts into a national registry and monitoring system. By tackling awareness levels, health beliefs, and religious perspectives, Jordan can implement effective interventions to improve BCS and outcomes for women nationwide. Ultimately, ongoing research to monitor screening trends is crucial for evaluating and enhancing health initiatives, providing valuable insights to inform future policies and programs.

This study contributes to the growing body of research on BCS in Jordan and similar contexts. It highlights significant barriers to mammogram screening among Jordanian women aged 40 years and older, including a lack of knowledge, cultural beliefs, and psychological and financial challenges. The study emphasizes the importance of establishing a solid foundation for culturally appropriate and sensitive interventions that are tailored to the local context and targeted to improve health awareness, accessibility, and policy reforms. Health care providers and policy makers can adopt an evidence-based approach to enhance early detection, reduce BC mortality rates, and promote a healthier future. Future research should focus on assessing the long-term effects of these initiatives.