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<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPH</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Public Health Surveill</journal-id>
      <journal-title>JMIR Public Health and Surveillance</journal-title>
      <issn pub-type="epub">2369-2960</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v8i1e25375</article-id>
      <article-id pub-id-type="pmid">34982721</article-id>
      <article-id pub-id-type="doi">10.2196/25375</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Original Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Ecological Momentary Assessment of Physical Activity and Wellness Behaviors in College Students Throughout a School Year: Longitudinal Naturalistic Study</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Kukafka</surname>
            <given-names>Rita</given-names>
          </name>
        </contrib>
        <contrib contrib-type="editor">
          <name>
            <surname>Eysenbach</surname>
            <given-names>Gunther</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Deshaw</surname>
            <given-names>Kathryn</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Liang</surname>
            <given-names>Yan</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Bai</surname>
            <given-names>Yang</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of Health and Kinesiology</institution>
            <institution>College of Health</institution>
            <institution>University of Utah</institution>
            <addr-line>HPER-North</addr-line>
            <addr-line>Room 204</addr-line>
            <addr-line>Salt Lake City, UT, 84102</addr-line>
            <country>United States</country>
            <phone>1 8015870482</phone>
            <email>yang.bai@utah.edu</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-6751-3896</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Copeland</surname>
            <given-names>William E</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1348-7781</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Burns</surname>
            <given-names>Ryan</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-5933-4633</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Nardone</surname>
            <given-names>Hilary</given-names>
          </name>
          <degrees>BSc</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-7631-663X</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Devadanam</surname>
            <given-names>Vinay</given-names>
          </name>
          <degrees>BA</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-2637-6797</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Rettew</surname>
            <given-names>Jeffrey</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-4238-5979</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author">
          <name name-style="western">
            <surname>Hudziak</surname>
            <given-names>James</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9653-758X</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Health and Kinesiology</institution>
        <institution>College of Health</institution>
        <institution>University of Utah</institution>
        <addr-line>Salt Lake City, UT</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Vermont Center for Children, Youth, and Families</institution>
        <institution>Division of Child Psychiatry</institution>
        <institution>University of Vermont</institution>
        <addr-line>Burlington, VT</addr-line>
        <country>United States</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Yang Bai <email>yang.bai@utah.edu</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>1</month>
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>4</day>
        <month>1</month>
        <year>2022</year>
      </pub-date>
      <volume>8</volume>
      <issue>1</issue>
      <elocation-id>e25375</elocation-id>
      <history>
        <date date-type="received">
          <day>29</day>
          <month>10</month>
          <year>2020</year>
        </date>
        <date date-type="rev-request">
          <day>17</day>
          <month>12</month>
          <year>2020</year>
        </date>
        <date date-type="rev-recd">
          <day>21</day>
          <month>1</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>15</day>
          <month>10</month>
          <year>2021</year>
        </date>
      </history>
      <copyright-statement>©Yang Bai, William E Copeland, Ryan Burns, Hilary Nardone, Vinay Devadanam, Jeffrey Rettew, James Hudziak. Originally published in JMIR Public Health and Surveillance (https://publichealth.jmir.org), 04.01.2022.</copyright-statement>
      <copyright-year>2022</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Public Health and Surveillance, is properly cited. The complete bibliographic information, a link to the original publication on https://publichealth.jmir.org, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://publichealth.jmir.org/2022/1/e25375" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>The Wellness Environment app study is a longitudinal study focused on promoting health in college students.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>The two aims of this study were (1) to assess physical activity (PA) variation across the days of the week and throughout the academic year and (2) to explore the correlates that were associated with PA, concurrently and longitudinally.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>The participants were asked to report their wellness and risk behaviors on a 14-item daily survey through a smartphone app. Each student was provided an Apple Watch to track their real time PA. Data were collected from 805 college students from Sept 2017 to early May 2018. PA patterns across the days of the week and throughout the academic year were summarized. Concurrent associations of daily steps with wellness or risk behavior were tested in the general linear mixed-effects model. The longitudinal, reciprocal association between daily steps and health or risk behaviors were tested with cross-lagged analysis.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>Female college students were significantly more active than male ones. The students were significantly more active during the weekday than weekend. Temporal patterns also revealed that the students were less active during Thanksgiving, winter, and spring breaks. Strong concurrent positive correlations were found between higher PA and self-reported happy mood, 8+ hours of sleep, ≥1 fruit and vegetable consumption, ≥4 bottles of water intake, and ≤2 hours of screen time (<italic>P</italic>&#60;.001). Similar longitudinal associations found that the previous day’s wellness behaviors independently predicted the following day’s higher PA except for mood. Conversely, the higher previous-day PA levels were associated with better mood, more fruit and vegetable consumption, and playing less music, but with higher liquor consumption the next day.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>This study provides a comprehensive surveillance of longitudinal PA patterns and their independent association with a variety of wellness and risk behaviors in college students.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>young adulthood</kwd>
        <kwd>wellness</kwd>
        <kwd>substance use</kwd>
        <kwd>Apple Watch</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>Research has shown that physical activity (PA) has numerous health and wellness benefits across the life span [<xref ref-type="bibr" rid="ref1">1</xref>-<xref ref-type="bibr" rid="ref4">4</xref>]. Despite this, few American college students meet public health recommendations for 150 minutes of moderate and vigorous PA per week [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref6">6</xref>]. Indeed, approximately 40% to 56% of college students participate in PA less than 2 times a week [<xref ref-type="bibr" rid="ref7">7</xref>]. College students also fail to meet the guidelines for a total of 10,000 steps per day [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref9">9</xref>].</p>
      <p>Being able to monitor individuals’ PA plays an important role on PA promotion initiatives [<xref ref-type="bibr" rid="ref10">10</xref>]. Wearable technologies, such as the Apple Watch (Apple Inc), provide valid estimates of steps, PA time, and energy expenditure under laboratory and free-living conditions, providing opportunities for individuals to self-monitor their behaviors [<xref ref-type="bibr" rid="ref11">11</xref>-<xref ref-type="bibr" rid="ref13">13</xref>]. Public health professionals have indicated that wearable devices may be a cost-effective intervention method for PA behavior change to improve health outcomes and facilitate high levels of interest and motivation for PA [<xref ref-type="bibr" rid="ref14">14</xref>]. However, studies examining the effectiveness of wearable devices in college students are conflicting. Kim et al [<xref ref-type="bibr" rid="ref15">15</xref>] found that wearing an activity monitor for 15 weeks did not improve PA relative to a control group. However, Pope et al [<xref ref-type="bibr" rid="ref16">16</xref>] implemented a 12-week, combined smartwatch and health education intervention on a sample of college students, aimed to improve PA, and found statistically significant increases in moderate-to-vigorous physical activity (MVPA) and improvements in other health behaviors or outcomes. The PA level among college students varied dramatically from daily 6-10 minutes to 46-57 minutes, depending on how the PA was measured [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>].</p>
      <p>PA tends to correlate with other health and risk behaviors; therefore, multicomponent approaches to improve health behaviors and lower-risk behaviors may yield greater effectiveness compared with targeting 1 behavior alone [<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref18">18</xref>]. The intercorrelation between PA and other health behaviors such as sleep, diet, and water consumption have been extensively explored in both cross-sectional and longitudinal studies where positive associations have been reported [<xref ref-type="bibr" rid="ref19">19</xref>-<xref ref-type="bibr" rid="ref21">21</xref>]. Conversely, the associations of risk behaviors such as smoking and alcohol consumption with PA have shown mixed results [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>].</p>
      <p>The longitudinal pattern and correlates of PA in college students may better inform future intervention work for designing ecological and multicomponent health behavior programs [<xref ref-type="bibr" rid="ref25">25</xref>]. To the best of our knowledge, no study has examined yearlong trajectories of PA using the Apple Watch and correlated the objective PA with other salient health and risk behaviors. Therefore, the primary purpose of this study was to document objective PA trajectories, assessed using the Apple Watch during the 2017-2018 academic year, in a sample of college students. The secondary purpose of this study was to assess the concurrent and longitudinal associations of PA and other health and risk behaviors.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Participants</title>
        <p>All participants were from the University of Vermont (UVM) Wellness Environment (WE) study during the 2017-18 academic year. Less than half of the recruited students were assigned to the WE group, and the remainder were assigned to the control group. WE is a neuroscience-inspired health promotion program that incentivizes students to adopt healthy lifestyles. All of the recruited participants had access to a smartphone app, developed to incentivize higher PA, consume a healthy snack after workout, drink more water, and engage in mindfulness activities. WE students were provided resources that included gym access located in the residence halls, group fitness classes, mindfulness classes, and fitness and nutrition mentors.</p>
        <p>Study inclusion criteria included full-time UVM undergraduates aged 18-25 years with an iPhone 5 (Appl Inc) or newer (for app compatibility and connection to Apple Watch). A total of 1952 students were originally recruited, and 805 participants (222 Male, 574 Female, and 9 students who chose not to disclose their gender) were included in this study. The study protocol was approved by the UVM Institutional Review Board.</p>
      </sec>
      <sec>
        <title>Instruments and Assessment</title>
        <sec>
          <title>Apple Watch</title>
          <p>All participating students received either a Series 0 or Series 1 Apple Watch. The Apple Watch is equipped with heart rate sensor, accelerometer, and gyroscope to track steps, heart rate, exercise minutes, active and resting energy expenditure, sedentary breaks, distance traveled, and stairs climbed. The students were asked to wear the Apple Watch during the 2017-2018 academic year.</p>
        </sec>
        <sec>
          <title>Daily Surveys</title>
          <p>A 14-item survey was distributed to all participants each night (opening from 7 PM to midnight) via the WE study app on their iPhone or Apple Watch. The survey collected data from 6 wellness behaviors (ie, minutes of exercise, minutes of mindfulness, minutes of music played or sang, fruits and vegetables consumed, hours of sleep, and amount of water consumed) and 7 risk behaviors (ie, cigarette use, consumption of alcoholic drinks, illicit drug use, shots of liquor, number of nonprescribed pills, marijuana use, and hours of screen time). Data informing the overall mood of the day (happy, ok, or sad day) were also included. The daily survey was not a previously validated survey but has been cross-validated with other validated surveys [<xref ref-type="bibr" rid="ref26">26</xref>]. The participants’ demographic data were also collected at baseline. Apple Watch and daily survey data collected from Oct 9, 2017, to May 13, 2018, were used in the current study, resulting in 216 days of data.</p>
        </sec>
      </sec>
      <sec>
        <title>Data Processing and Analysis</title>
        <p>The data were analyzed in 2020. Daily step data were accessed via Apple’s HealthKit application programming interface and screened for compliance. A daily step total of 2000 was used as the wear time cut-off point [<xref ref-type="bibr" rid="ref27">27</xref>]. The students who had a minimum of 50 valid days of Apple Watch data and completed at least 50% of the daily surveys were included in the final sample. The inclusion criterion of 50 days was the median compliance rate that 50% of the participants (n=1952) had at least 50 days of valid Apple Watch data. Descriptive statistics for demographic variables including age, inclusion in wellness program, gender, race, and year in college as well as average daily steps were computed.</p>
        <p>Concurrent associations of daily steps with each wellness or risk behavior were tested first using a general linear mixed effects univariable model (1 behavior as a single predictor). This was followed using a multivariable model (all behaviors entered the same time as multiple predictors) with all 13 wellness and risk behaviors, except for exercise, tested simultaneously.</p>
        <p>Longitudinal, reciprocal associations between daily steps and health or risk behaviors were tested with cross-lagged analysis to explore whether the previous-day health and risk behaviors predict the next-day PA and vice versa. The intraclass correlation coefficient was 23.4% in the unconditional model, indicating that 23.4% of the variance in daily steps was between the participants. Thus, all analyses of the daily surveys accounted for repeated, correlated observations within individuals. An autoregressive covariance structure was used, and demographic variables were controlled for all of the mixed models [<xref ref-type="bibr" rid="ref28">28</xref>]. All analyses were conducted with SAS 9.4 (SAS Institute) software with an alpha value set at <italic>P</italic>&#60;.05.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Sample Description</title>
        <p>A total of 805 participants with at least 50% daily survey completion and 50 days of valid steps data were included in the analytic sample, which resulted in 77,857 total participant-days’ worth of observations. The analytic sample included in the study did not differ from the baseline sample (N=1871) in terms of demographic distribution (ie, academic year, gender, involvement in the WE program, and race). The average number of observations per participant throughout the 2017-18 academic year was 97 days (SD 48, range 50-212). Overall, the majority of the study sample were female (72.1%), Caucasian (85.4%), and freshman (60.8%) or sophomore (21.8%) (<xref ref-type="table" rid="table1">Table 1</xref>). No statistical differences were found in the average steps between races, academic class standing, and involvement in the WE program. The only significant difference was that female participants had higher average steps than males (<italic>P</italic>&#60;.001)<italic>.</italic></p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Average daily steps stratified by sample characteristics.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="250"/>
            <col width="220"/>
            <col width="160"/>
            <col width="190"/>
            <col width="150"/>
            <thead>
              <tr valign="top">
                <td colspan="3">Characteristics and populations</td>
                <td colspan="3">Other values</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <break/>
                </td>
                <td>Mean steps</td>
                <td>95% CI</td>
                <td><italic>P</italic> value</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="3">
                  <bold>Gender, n (%)</bold>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Male</td>
                <td>222 (27.9)</td>
                <td>8488</td>
                <td>(8227-8749)</td>
                <td>Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Female</td>
                <td>574 (72.1)</td>
                <td>8904</td>
                <td>(8739-9069)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="2">
                  <bold>WE<sup>a</sup> status, n (%)</bold>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Wellness Environment</td>
                <td>351 (43.6)</td>
                <td>8833</td>
                <td>(8624-9042)</td>
                <td>Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>College as usual</td>
                <td>454 (56.4)</td>
                <td>8731</td>
                <td>(8545-8917)</td>
                <td>.47</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Academic year, n (%)</bold>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>First year of college</td>
                <td>486 (60.8)</td>
                <td>8826</td>
                <td>(8650-9010)</td>
                <td>Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Second year of college</td>
                <td>174 (21.8)</td>
                <td>8800</td>
                <td>(8538-9131)</td>
                <td>.98</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Third year of college</td>
                <td>113 (14.1)</td>
                <td>8539</td>
                <td>(8160-8902)</td>
                <td>.15</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Fourth year of college</td>
                <td>26 (3.3)</td>
                <td>8588</td>
                <td>(7908-9456)</td>
                <td>.71</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Race, n (%)</bold>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Caucasian</td>
                <td>677 (85.4)</td>
                <td>8770</td>
                <td>(8624-8927)</td>
                <td>Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>African American</td>
                <td>12 (1.5)</td>
                <td>9030</td>
                <td>(7992-10,072)</td>
                <td>.63</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Asian</td>
                <td>53 (6.7)</td>
                <td>8714</td>
                <td>(8231-9361)</td>
                <td>.95</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Latina or Latino</td>
                <td>22 (2.8)</td>
                <td>8571</td>
                <td>(7851-9452)</td>
                <td>.77</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Native American</td>
                <td>4 (0.5)</td>
                <td>8388</td>
                <td>(6307-10,469)</td>
                <td>.72</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Pacific Islander</td>
                <td>3 (0.4)</td>
                <td>11,223</td>
                <td>(8827-13,620)</td>
                <td>.05</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Other</td>
                <td>22 (2.8)</td>
                <td>8672</td>
                <td>(7796-9472)</td>
                <td>.74</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>WE: Wellness Environment.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Prevalence of Daily Steps</title>
        <p>Steps were tracked daily and across the entire year (<xref rid="figure1" ref-type="fig">Figure 1</xref>). The participants were more active during the weekdays (Monday to Friday, ranged from 8989 to 9566), and their daily steps were approximately 1000 fewer on Saturdays (8533, SD 286) and an additional 800 fewer steps on Sundays (7327, SD 286) compared with weekday steps. A larger variation was found across the school year. Step counts were significantly lower during school breaks including Thanksgiving (6999, SD 338), winter break (6471, SD 345), and spring break (7725, SD 341). The most active period was the first 3 weeks of the study, which ranged from 10,697 to 10,864 steps daily. Gender difference attenuated during the weekends and breaks. Compared with males, female participants accumulated about 1500 more steps during weekdays and over 1100 more steps on Saturdays and Sundays.</p>
        <p>Note that the daily steps were averaged into weekdays with data from the entire academic year (<xref rid="figure1" ref-type="fig">Figure 1</xref>a), and the daily steps were averaged into study weeks (<xref rid="figure1" ref-type="fig">Figure 1</xref>b).</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>The prevalence of daily steps across day of the week (a) and the academic year (b) by gender.</p>
          </caption>
          <graphic xlink:href="publichealth_v8i1e25375_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Concurrent Associations of Daily Steps With Wellness or Risk Behaviors</title>
        <p>The association of daily steps with 1 wellness or risk behavior (<xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>: Supplemental Table 1) in the univariable model was similar to that of the steps with multiple behaviors in the multivariable model (<xref ref-type="table" rid="table2">Table 2</xref>). Higher levels of PA were associated with happy mood (&#62;650 daily steps) and other health behaviors, including ≥1 servings of fruits and vegetables, ≥4 glasses of water, and ≥1 minute of mindfulness practice (<italic>P</italic>&#60;.001). A dose-response association was also found between PA with fruit and water consumption. Nonacademic screen time was negatively associated with daily steps in that a difference of over 2000 steps was found between the participants who spent 0-2 hours and 7+ hours on screen (<italic>P</italic>&#60;.001).</p>
        <p>Moreover, 3 out of 6 substance abuse behaviors (ie, liquor, cannabis, and nonprescribed pills) were significantly associated with PA (<italic>P</italic>&#60;.001). For 30 minutes of self-report exercise, there was approximately 1700 additional steps estimated by Apple Watch (<italic>P</italic>&#60;.001). The cumulative wellness items had a positive association with daily steps (<italic>P</italic>&#60;.001). The participants were most active when they had 0 risk behaviors (9338 steps; 95% CI 8748-9928) followed by those who engaged 2 and more risk behaviors (8855 steps; 95% CI 8257-9452) and then 1 risk behavior (8508 steps; 95% CI 7918-9099).</p>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Healthy and risky behaviors predicting daily steps within the multivariate model.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="300"/>
            <col width="0"/>
            <col width="240"/>
            <col width="0"/>
            <col width="250"/>
            <col width="0"/>
            <col width="180"/>
            <thead>
              <tr valign="bottom">
                <td colspan="3"> Healthy and risky behaviors<sup>a</sup></td>
                <td colspan="2">Estimated steps</td>
                <td colspan="2">95% CI</td>
                <td><italic>P</italic> value</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="3">
                  <bold>Mood</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Sad</td>
                <td colspan="2">8535</td>
                <td colspan="2">(7774-9295)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Ok</td>
                <td colspan="2">8622</td>
                <td colspan="2">(7867-9378)</td>
                <td colspan="2">.17</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Happy</td>
                <td colspan="2">9189</td>
                <td colspan="2">(8434-9944)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Sleep (hours)</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>&#60;4</td>
                <td colspan="2">9194</td>
                <td colspan="2">(8419-9969)</td>
                <td colspan="2">.51</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>4-7</td>
                <td colspan="2">9125</td>
                <td colspan="2">(8372-9879)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>8+</td>
                <td colspan="2">8027</td>
                <td colspan="2">(7273-8780)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Fruit, n</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>0</td>
                <td colspan="2">8169</td>
                <td colspan="2">(7412-8927)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>1-3</td>
                <td colspan="2">8798</td>
                <td colspan="2">(8044-9552)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>4+</td>
                <td colspan="2">9378</td>
                <td colspan="2">(8619-10,138)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Water, n</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>0-3</td>
                <td colspan="2">8105</td>
                <td colspan="2">(7349-8861)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>4-6</td>
                <td colspan="2">8824</td>
                <td colspan="2">(8069-9579)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>7+</td>
                <td colspan="2">9416</td>
                <td colspan="2">(8655-10,177)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Screen time (hours)</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>0-2</td>
                <td colspan="2">9848</td>
                <td colspan="2">(9094-10,601)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>3-6</td>
                <td colspan="2">8859</td>
                <td colspan="2">(8104-9613)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>7+</td>
                <td colspan="2">7639</td>
                <td colspan="2">(6871-8408)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Mindfulness (minutes)</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>0</td>
                <td colspan="2">8386</td>
                <td colspan="2">(7632-9141)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>1-9</td>
                <td colspan="2">9009</td>
                <td colspan="2">(8251-9767)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>10+</td>
                <td colspan="2">8951</td>
                <td colspan="2">(8191-9711)</td>
                <td colspan="2">.02</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Music (minutes)</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>0</td>
                <td colspan="2">8752</td>
                <td colspan="2">(7996-9508)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>1-30</td>
                <td colspan="2">8731</td>
                <td colspan="2">(7974-9487)</td>
                <td colspan="2">.64</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>31+</td>
                <td colspan="2">8863</td>
                <td colspan="2">(8106-9620)</td>
                <td colspan="2">.04</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Alcohol</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8811</td>
                <td colspan="2">(8057-9565)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8753</td>
                <td colspan="2">(7992-9513)</td>
                <td colspan="2">.41</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Liquor</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8487</td>
                <td colspan="2">(7733-9242)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">9077</td>
                <td colspan="2">(8313-9840)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Marijuana</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8674</td>
                <td colspan="2">(7919-9430)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8890</td>
                <td colspan="2">(8128-9651)</td>
                <td colspan="2">.01</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Cigarettes</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8724</td>
                <td colspan="2">(7973-9474)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8840</td>
                <td colspan="2">(8042-9638)</td>
                <td colspan="2">.52</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Illicit drugs</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8881</td>
                <td colspan="2">(8219-9544)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8682</td>
                <td colspan="2">(7660-9704)</td>
                <td colspan="2">.64</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Nonprescribed pills</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">9169</td>
                <td colspan="2">(8434-9904)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8395</td>
                <td colspan="2">(7542-9248)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Gender</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Male</td>
                <td colspan="2">8519</td>
                <td colspan="2">(7729-9308)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Female</td>
                <td colspan="2">9045</td>
                <td colspan="2">(8287-9803)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>WE<sup>b</sup> status</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Wellness Environment</td>
                <td colspan="2">8712</td>
                <td colspan="2">(7918-9506)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>College as usual</td>
                <td colspan="2">8852</td>
                <td colspan="2">(8097-9607)</td>
                <td colspan="2">.44</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Academic year</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>First year of college</td>
                <td colspan="2">9074</td>
                <td colspan="2">(8333-9816)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Second year of college</td>
                <td colspan="2">8752</td>
                <td colspan="2">(7967-9537)</td>
                <td colspan="2">.12</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Third year of college</td>
                <td colspan="2">8644</td>
                <td colspan="2">(7819-9468)</td>
                <td colspan="2">.09</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Fourth year of college</td>
                <td colspan="2">8658</td>
                <td colspan="2">(75552-9764)</td>
                <td colspan="2">.36</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Race</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Caucasian</td>
                <td colspan="2">8360</td>
                <td colspan="2">(7797-8922)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>African American</td>
                <td colspan="2">8596</td>
                <td colspan="2">(7264-9927)</td>
                <td colspan="2">.71</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Asian</td>
                <td colspan="2">8429</td>
                <td colspan="2">(7626-9232)</td>
                <td colspan="2">.83</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Latina or Latino</td>
                <td colspan="2">8435</td>
                <td colspan="2">(7383-9487)</td>
                <td colspan="2">.87</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Native American</td>
                <td colspan="2">8110</td>
                <td colspan="2">(5914-10,305)</td>
                <td colspan="2">.82</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Pacific Islander</td>
                <td colspan="2">11,039</td>
                <td colspan="2">(8502-13,575)</td>
                <td colspan="2">.03</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Other</td>
                <td colspan="2">8506</td>
                <td colspan="2">(7391-9622)</td>
                <td colspan="2">.77</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>Demographic factors were controlled in the model.</p>
            </fn>
            <fn id="table2fn2">
              <p><sup>b</sup>WE: Wellness Environment.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Longitudinal Associations of Daily Steps With Wellness of Risk Behaviors</title>
        <p>The previous-day behaviors predicting the next day’s PA were tested using both univariable (<xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>: Supplemental Table 2) and multivariable models (<xref ref-type="table" rid="table3">Table 3</xref>). The results indicated that each of the self-reported behaviors independently predicted the next day’s PA. As shown in <xref ref-type="table" rid="table3">Table 3</xref>, the previous-day fruit and vegetable consumption, water consumption, and mindfulness practice had significantly positive associations with the following day’s PA. The students who had 1-3 and 4+ servings of fruit and vegetables accumulated 656 and 375 more following-day steps compared with students who had no fruit and vegetable consumption, respectively (<italic>P</italic>&#60;.001). Similarly, the students who had 7+ bottles of water accumulated 335 and 215 additional following-day steps compared with those who had 0-3 and 4-6 bottles of water (<italic>P</italic>&#60;.001). The previous-day screen time was a negative predictor of the following-day PA. The students who had 3-6 hours and 7+ hours of screen time accumulated 203 and 506 fewer following-day steps compared with those who had 0-2 hours of screen time (<italic>P</italic>&#60;.001). The students with any mindfulness practice had 300-400 additional following-day steps compared with those who had no mindfulness practice (<italic>P</italic>&#60;.001). However, Students who were happy or played music predicted lower following-day PA compared with those who had a sad mood or played no music. Previous-day cigarettes and illicit drugs did not significantly predict the following day’s PA (<xref ref-type="table" rid="table3">Table 3</xref>). Conversely, higher previous-day PA levels were associated with less following-day exercise, higher fruit and vegetable consumption, less playing music, and higher liquor consumption (<italic>P</italic>&#60;.05, <xref ref-type="table" rid="table4">Table 4</xref>).</p>
        <table-wrap position="float" id="table3">
          <label>Table 3</label>
          <caption>
            <p>Previous-day healthy and risky behaviors predicting daily steps in multivariate model.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="420"/>
            <col width="0"/>
            <col width="190"/>
            <col width="0"/>
            <col width="230"/>
            <col width="0"/>
            <col width="130"/>
            <thead>
              <tr valign="bottom">
                <td colspan="3"> Previous-day healthy and risky behaviors<sup>a</sup></td>
                <td colspan="2">Estimated steps</td>
                <td colspan="2">95% CI</td>
                <td><italic>P</italic> values</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="3">Steps</td>
                <td colspan="2">0.2</td>
                <td colspan="2">(0.19-0.21)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Mood</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Sad</td>
                <td colspan="2">8788</td>
                <td colspan="2">(8033-9543)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Ok</td>
                <td colspan="2">8812</td>
                <td colspan="2">(8064-9559)</td>
                <td colspan="2">.75</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Happy</td>
                <td colspan="2">8487</td>
                <td colspan="2">(7740-9234)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Sleep (hours)</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>&#60;4</td>
                <td colspan="2">8600</td>
                <td colspan="2">(7827-9373)</td>
                <td colspan="2">.27</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>4-7</td>
                <td colspan="2">8736</td>
                <td colspan="2">(7991-9481)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>8+</td>
                <td colspan="2">8751</td>
                <td colspan="2">(8005-9497)</td>
                <td colspan="2">.70</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Fruit, n</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>0</td>
                <td colspan="2">8383</td>
                <td colspan="2">(7633-9134)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>1-3</td>
                <td colspan="2">8664</td>
                <td colspan="2">(7918-9411)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>4+</td>
                <td colspan="2">9039</td>
                <td colspan="2">(8286-9792)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Water, n</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>0-3</td>
                <td colspan="2">8544</td>
                <td colspan="2">(7796-9292)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>4-6</td>
                <td colspan="2">8664</td>
                <td colspan="2">(7916-9411)</td>
                <td colspan="2">.03</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>7+</td>
                <td colspan="2">8879</td>
                <td colspan="2">(8124-9634)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Screen time (hours)</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>0-2</td>
                <td colspan="2">8932</td>
                <td colspan="2">(8187-9677)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>3-6</td>
                <td colspan="2">8729</td>
                <td colspan="2">(7983-9476)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>7h+</td>
                <td colspan="2">8426</td>
                <td colspan="2">(7661-9191)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Mindfulness (minutes)</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>0</td>
                <td colspan="2">8460</td>
                <td colspan="2">(8140-9642)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>1-9</td>
                <td colspan="2">8891</td>
                <td colspan="2">(9066-10,036)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>10+</td>
                <td colspan="2">8737</td>
                <td colspan="2">(7983-9490)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Music (minutes)</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>0</td>
                <td colspan="2">8803</td>
                <td colspan="2">(8055-9551)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>1-30</td>
                <td colspan="2">8697</td>
                <td colspan="2">(7947-9446)</td>
                <td colspan="2">.04</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>31+</td>
                <td colspan="2">8587</td>
                <td colspan="2">(7837-9336)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Alcohol</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8945</td>
                <td colspan="2">(8200-9691)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8446</td>
                <td colspan="2">(7690-9202)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Liquor</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8921</td>
                <td colspan="2">(8175-9668)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8470</td>
                <td colspan="2">(7710-9230)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Marijuana</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8804</td>
                <td colspan="2">(8055-9553)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8587</td>
                <td colspan="2">(7832-9342)</td>
                <td colspan="2">.03</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Cigarettes</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8612</td>
                <td colspan="2">(7869-9355)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8779</td>
                <td colspan="2">(7973-9586)</td>
                <td colspan="2">.44</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Illicit drugs</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8678</td>
                <td colspan="2">(8071-9286)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8713</td>
                <td colspan="2">(7587-9839)</td>
                <td colspan="2">.95</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Nonprescribed pills</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>No</td>
                <td colspan="2">8932</td>
                <td colspan="2">(8207-9657)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Yes</td>
                <td colspan="2">8459</td>
                <td colspan="2">(7577-9340)</td>
                <td colspan="2">.13</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Gender</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Male</td>
                <td colspan="2">8535</td>
                <td colspan="2">(7766-9304)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Female</td>
                <td colspan="2">8857</td>
                <td colspan="2">(8107-9606)</td>
                <td colspan="2">.03</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>WE<sup>b</sup> status</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Wellness Environment</td>
                <td colspan="2">8595</td>
                <td colspan="2">(7821-9370)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>College as usual</td>
                <td colspan="2">8796</td>
                <td colspan="2">(8050-9542)</td>
                <td colspan="2">.18</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Academic year</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>First year of college</td>
                <td colspan="2">8852</td>
                <td colspan="2">(8114-9590)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Second year of college</td>
                <td colspan="2">8664</td>
                <td colspan="2">(7897-9431)</td>
                <td colspan="2">.27</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Third year of college</td>
                <td colspan="2">8444</td>
                <td colspan="2">(7650-9239)</td>
                <td colspan="2">.05</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Fourth year of college</td>
                <td colspan="2">8822</td>
                <td colspan="2">(7824-9820)</td>
                <td colspan="2">.94</td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Race</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Caucasian</td>
                <td colspan="2">8482</td>
                <td colspan="2">(7858-9105)</td>
                <td colspan="2">Reference</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>African American</td>
                <td colspan="2">8472</td>
                <td colspan="2">(7290-9654)</td>
                <td colspan="2">.99</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Asian</td>
                <td colspan="2">8494</td>
                <td colspan="2">(7715-9274)</td>
                <td colspan="2">.96</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Latina or Latino</td>
                <td colspan="2">8256</td>
                <td colspan="2">(7290-9221)</td>
                <td colspan="2">.56</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Native American</td>
                <td colspan="2">7969</td>
                <td colspan="2">(6139-9799)</td>
                <td colspan="2">.56</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Pacific Islander</td>
                <td colspan="2">10,529</td>
                <td colspan="2">(8414-12,644)</td>
                <td colspan="2">.05</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Other</td>
                <td colspan="2">8667</td>
                <td colspan="2">(7657-9678)</td>
                <td colspan="2">.65</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table3fn1">
              <p><sup>a</sup>Demographic factors were controlled in the model.</p>
            </fn>
            <fn id="table3fn2">
              <p><sup>b</sup>WE: Wellness Environment.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table4">
          <label>Table 4</label>
          <caption>
            <p>Previous day daily steps predicting healthy and risky behaviors within the univariable model.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="340"/>
            <col width="250"/>
            <col width="280"/>
            <col width="130"/>
            <thead>
              <tr valign="top">
                <td> </td>
                <td colspan="3">Previous day steps as predictor<sup>a</sup></td>
              </tr>
              <tr valign="top">
                <td>Outcomes</td>
                <td>Coefficient</td>
                <td>95% CI</td>
                <td><italic>P</italic> value</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Mood</td>
                <td>-0.0049</td>
                <td>(-0.013, 0.0031)</td>
                <td>.07</td>
              </tr>
              <tr valign="top">
                <td>Sleep</td>
                <td>-0.0001</td>
                <td>(-0.0079, 0.0077)</td>
                <td>.98</td>
              </tr>
              <tr valign="top">
                <td>Exercise</td>
                <td>-0.010</td>
                <td>(-0.018, -0.0027)</td>
                <td>.01</td>
              </tr>
              <tr valign="top">
                <td>Fruit</td>
                <td>0.011</td>
                <td>(0.0033, 0.018)</td>
                <td>.01</td>
              </tr>
              <tr valign="top">
                <td>Water</td>
                <td>0.0047</td>
                <td>(-0.0032, 0.013)</td>
                <td>.24</td>
              </tr>
              <tr valign="top">
                <td>Screen time</td>
                <td>0.0070</td>
                <td>(-0.001, 0.015)</td>
                <td>.09</td>
              </tr>
              <tr valign="top">
                <td>Mindfulness</td>
                <td>-0.0080</td>
                <td>(-0.018, 0.0016)</td>
                <td>.10</td>
              </tr>
              <tr valign="top">
                <td>Music</td>
                <td>-0.0096</td>
                <td>(-0.018, -0.0014)</td>
                <td>.02</td>
              </tr>
              <tr valign="top">
                <td>Alcohol</td>
                <td>0.013</td>
                <td>(-0.0003, 0.027)</td>
                <td>.06</td>
              </tr>
              <tr valign="top">
                <td>Liquor</td>
                <td>0.027</td>
                <td>(0.015, 0.038)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>Marijuana</td>
                <td>0.0095</td>
                <td>(-0.007, 0.026)</td>
                <td>.25</td>
              </tr>
              <tr valign="top">
                <td>Cigarettes</td>
                <td>0.011</td>
                <td>(-0.013, 0.035)</td>
                <td>.36</td>
              </tr>
              <tr valign="top">
                <td>Illicit drugs</td>
                <td>0.029</td>
                <td>(-0.006, 0.063)</td>
                <td>.11</td>
              </tr>
              <tr valign="top">
                <td>Nonprescribed pills</td>
                <td>-0.011</td>
                <td>(-0.038, 0.017)</td>
                <td>.45</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table4fn1">
              <p><sup>a</sup>Demographic factors were controlled in the models.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>This paper provided a unique and comprehensive profile of objectively measured daily PA and self-reported health and risk behaviors using ecological momentary assessment over 7 months within 1 academic year among college students. We found PA variations between the weekday and weekend and between school days and academic breaks. Gender differences in PA were attenuated during the weekend and academic breaks. Compared with risk behaviors, stronger and independent associations were found between PA and several wellness behaviors including self-report exercise minutes, fruit and vegetable consumption, sleep, water consumption, and mood states.</p>
        <p>Although consumer monitors provide the potential to track PA in real time during longer time periods, few studies have reported continuously monitored PA levels (ie, for more than a few weeks) in adult or youth populations. Several studies have applied consumer monitors such as Fitbit (Fitbit Inc) or Misfit (Misfit Inc) in intervention studies lasting from 12 weeks to 6 months, but the majority of the studies have used research-based activity monitors (eg, Actigraph) and only reported baseline and posttest MVPA [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref29">29</xref>]. Three intervention studies used Fitbit and reported the real-time steps or MVPA data over 1 year [<xref ref-type="bibr" rid="ref30">30</xref>], 12 weeks [<xref ref-type="bibr" rid="ref31">31</xref>], and 8 weeks [<xref ref-type="bibr" rid="ref32">32</xref>]. Although direct comparisons to this study are precluded due to the sample and setting differences, there may have been possible behavioral reactivity within in the first 2 or 3 weeks of wearing the device [<xref ref-type="bibr" rid="ref30">30</xref>-<xref ref-type="bibr" rid="ref32">32</xref>]. No other prior ecological momentary assessment of PA studies in college students were identified.</p>
        <p>Similar to 2 other recent intervention studies with college students using wearables [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>], around 70% of the participants in this study were female. Mixed results were found in the literature about gender differences and PA levels among college students. The majority of previous research using self-report data suggested that males were more active than females; however, studies using objectively measured PA found either no gender differences or females being more active than males [<xref ref-type="bibr" rid="ref33">33</xref>-<xref ref-type="bibr" rid="ref35">35</xref>]. Our study showed that female participants were more active than their male counterparts during the week and across the school year. Possible explanations for these differences could be that males tend to overestimate their PA levels in the self-report data, and they tend to engage in resistance training, which is a nonambulatory activity that may not be captured by the Apple Watch [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref36">36</xref>].</p>
        <p>Our study also found that the participants were more active during structured days (ie, school days) than unstructured days (ie, academic breaks and weekends). A few other studies also observed that college students were more active during weekdays than weekends [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>]. For example, Clemente et al [<xref ref-type="bibr" rid="ref37">37</xref>] found that both male and female Portuguese college students were more active during weekdays than weekend days. However, this finding was expected because most students had to walk to or around campus during weekdays [<xref ref-type="bibr" rid="ref34">34</xref>]. Despite this, we did not find empirical studies that examined the seasonal patterns of objective PA in a college sample, which may be due to prior measurement constraints such as the lack of technology to continuously monitor PA over several months with research-based monitors.</p>
        <p>Besides environmental changes, university students, especially first-year students, undergo social, academic, emotional, and physiological changes that may influence their lifestyle and behaviors such as higher stress levels leading to increased drug and alcohol abuse [<xref ref-type="bibr" rid="ref38">38</xref>]. Young adults had the highest prevalence (13.1%) of major depressive episodes compared with other adult age groups, according to the data from 2017 National Survey on Drug Use and Health [<xref ref-type="bibr" rid="ref39">39</xref>]. Several randomized controlled trials indicated the small-to-moderate therapeutic effects of exercise on depression and anxiety disorders [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref41">41</xref>]. Our study indicated that students who had higher PA had better current and next day mood. Encouraging college students to engage in PA or exercise could be an effective way to cope with academic and interpersonal stress during the transition from high school to college.</p>
        <p>The magnitude of association of PA and other wellness and risk behaviors remained generally consistent in the univariable and multivariable models, supporting the independent association between PA and wellness and risk behaviors in college students. For PA and health behaviors, fruit, vegetable, and water consumption were positively correlated with PA levels while screen time was negatively associated with PA, which have been confirmed by other cross-sectional studies [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref42">42</xref>]. However, the significant temporal link between PA and fruit or vegetable consumptions found in our study contradicted the findings of previous studies in the literature [<xref ref-type="bibr" rid="ref19">19</xref>]. Congruent with prior research, our study also found that PA levels decreased from freshman to senior year. This indicates the importance of offering health behavior education and promotion programming to freshmen, targeting several health and risk behaviors [<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref44">44</xref>]. Unlike other studies [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref42">42</xref>], our study did not find significant associations between PA and risk behaviors. Notwithstanding, PA was identified as a protective factor for alcohol and substance use behaviors in our temporal analysis. A possible explanation is that the majority of the study sample were freshmen who live on campus, half of whom reside in WE housing where students sign a contract not to consume alcohol in their dorm. Thus, those students who wanted to consume alcohol needed to walk to bars, parties, and stores, increasing their daily step count.</p>
      </sec>
      <sec>
        <title>Strengths and Limitations</title>
        <p>To the best of our knowledge, this is the first study using an ecological momentary approach to assess multiple wellness behaviors in 1 academic year among college students. The study assessed real time and objective PA within a real-world setting over a full academic year in addition to the tracking of other wellness and risk behaviors. Academic breaks and weekends were identified as inactive periods for college students, which allows targeted interventions to be designed to enhance the health of young adults during this critical life transition period. The successful deployment of the study app allowed us to collect 13 different wellness behaviors and mood states simultaneously on a daily basis. This enabled us to study the different wellness behaviors’ independent and dependent associations as well as concurrent and longitudinal associations with PA.</p>
        <p>There are a number of limitations in this study. First, the study sample was generally homogeneous with a majority of participants being female and Caucasian at a single university in Northeastern United States. Second, the Apple Watch provided objectively measured step count data, but no wear time data were available to assess. Considering the possible linear association of longer wear time and higher number of steps accumulated, the activity level could be skewed for students who wore the Apple Watch longer and slept less. Third, the wellness and risk behaviors were measured by self-report daily survey items with fixed response sets.</p>
      </sec>
      <sec>
        <title>Implications and Contribution</title>
        <p>The independent associations explored between PA and a variety of other health-related behaviors indicated that promoting one behavior will not necessarily influence other behaviors. This study provided novel information on specific patterns of college students’ objective PA, wellness, and risk behaviors over an academic year.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Healthy and risky behaviors predicting daily steps within the univariable model.&#13;
Previous day healthy and risky behaviors predicting daily steps within the univariable model.</p>
        <media xlink:href="publichealth_v8i1e25375_app1.docx" xlink:title="DOCX File , 21 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">MVPA</term>
          <def>
            <p>moderate-to-vigorous physical activity</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">PA</term>
          <def>
            <p>physical activity</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">UVM</term>
          <def>
            <p>University of Vermont</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">WE</term>
          <def>
            <p>Wellness Environment</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <fn-group>
      <fn fn-type="conflict">
        <p>This study was supported by a research grant from the Conrad Hilton Foundation. The funding source had no involvement in the study design, data collection, analysis and interpretation of data, writing of the report, or the decision to submit the article for publication. YB had full access to all the data in the study, performed all statistical analyses, and takes responsibility for the integrity of the data and the accuracy of the data analysis. WEC receives research support from the National Institute of Mental Health, National Institute on Drug Abuse, and the National Institute for Child Health and Development. JH receives research grants from the Conrad Hilton Foundation and Apple Corp.</p>
      </fn>
    </fn-group>
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