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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JPH</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Public Health Surveill</journal-id>
      <journal-title>JMIR Public Health and Surveillance</journal-title>
      <issn pub-type="epub">2369-2960</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v5i1e11313</article-id>
      <article-id pub-id-type="pmid">30785405</article-id>
      <article-id pub-id-type="doi">10.2196/11313</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Rapid Surveillance Report</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Rapid Surveillance Report</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>The Annual American Men's Internet Survey of Behaviors of Men Who Have Sex With Men in the United States: 2016 Key Indicators Report</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Lansky</surname>
            <given-names>Amy</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Tregear</surname>
            <given-names>Stephen</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Callander</surname>
            <given-names>Denton</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="author" id="contrib1" corresp="yes">
          <name name-style="western">
            <surname>Zlotorzynska</surname>
            <given-names>Maria</given-names>
          </name>
          <degrees>MPH, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of Epidemiology</institution>
            <institution>Rollins School of Public Health</institution>
            <institution>Emory University</institution>
            <addr-line>1518 Clifton Rd NE</addr-line>
            <addr-line>Atlanta, GA, 30322</addr-line>
            <country>United States</country>
            <phone>1 4047278799</phone>
            <email>mzlotor@emory.edu</email>
          </address>
          <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-3245-0175</ext-link>
        </contrib>
        <contrib contrib-type="author" id="contrib2">
          <name name-style="western">
            <surname>Sullivan</surname>
            <given-names>Patrick</given-names>
          </name>
          <degrees>DVM, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-7728-0587</ext-link>
        </contrib>
        <contrib contrib-type="author" id="contrib3">
          <name name-style="western">
            <surname>Sanchez</surname>
            <given-names>Travis</given-names>
          </name>
          <degrees>MPH, DVM</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">http://orcid.org/0000-0003-1133-4762</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
      <label>1</label>
      <institution>Department of Epidemiology</institution>
      <institution>Rollins School of Public Health</institution>  
      <institution>Emory University</institution>  
      <addr-line>Atlanta, GA</addr-line>
      <country>United States</country></aff>
      <author-notes>
        <corresp>Corresponding Author: Maria Zlotorzynska 
        <email>mzlotor@emory.edu</email></corresp>
      </author-notes>
      <pub-date pub-type="collection"><season>Jan-Mar</season><year>2019</year></pub-date>
      <pub-date pub-type="epub">
        <day>20</day>
        <month>02</month>
        <year>2019</year>
      </pub-date>
      <volume>5</volume>
      <issue>1</issue>
      <elocation-id>e11313</elocation-id>
      <!--history from ojs - api-xml-->
      <history>
        <date date-type="received">
          <day>16</day>
          <month>6</month>
          <year>2018</year>
        </date>
        <date date-type="rev-request">
          <day>14</day>
          <month>8</month>
          <year>2018</year>
        </date>
        <date date-type="rev-recd">
          <day>28</day>
          <month>11</month>
          <year>2018</year>
        </date>
        <date date-type="accepted">
          <day>30</day>
          <month>11</month>
          <year>2018</year>
        </date>
      </history>
      <copyright-statement>©Maria Zlotorzynska, Patrick Sullivan, Travis Sanchez. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 20.02.2019.</copyright-statement>
      <copyright-year>2019</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Public Health and Surveillance, is properly cited. The complete bibliographic information, a link to the original publication on http://publichealth.jmir.org, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="http://publichealth.jmir.org/2019/1/e11313/" xlink:type="simple"/>
      <abstract>
        <p>The American Men’s Internet Survey (AMIS) is an annual Web-based behavioral survey of men who have sex with men (MSM) living in the United States. This Rapid Surveillance Report describes the fourth cycle of data collection (September 2016 through February 2017; AMIS 2016). The key indicators are the same as previously reported for AMIS (December 2013 through May 2014, AMIS 2013; November 2014 through April 2015, AMIS 2014; and September 2015 through April 2016, AMIS 2015). The AMIS survey methodology has not substantively changed since AMIS 2015. MSM were recruited from a variety of websites using banner advertisements and email blasts. Additionally, participants from AMIS 2015 who agreed to be recontacted for future research were emailed a link to the AMIS 2016 survey. Men were eligible to participate if they were ≥15 years old, resided in the United States, provided a valid US zone improvement plan code, and reported ever having sex with a man or identified as gay or bisexual. We examined demographic and recruitment characteristics using multivariable regression modeling (<italic>P</italic>&lt;.05) stratified by participants’ self-reported HIV status. The AMIS 2016 round of data collection resulted in 10,166 completed surveys from MSM representing every US state, Puerto Rico, Guam, and the US Virgin Islands. Participants were mainly non-Hispanic white, over the age of 40 years, living in the Southern United States and urban areas, and recruited from general social networking websites. Self-reported HIV prevalence was 10.80% (1098/10,166). Compared to HIV-negative/unknown-status participants, HIV-positive participants were more likely to have had anal sex without a condom with a male partner in the past 12 months (75.77% vs 65.88%, <italic>P</italic>&lt;.001) and more likely to have had anal sex without a condom with a serodiscordant or unknown-status partner (33.24% vs 16.06%, <italic>P</italic>&lt;.001). The reported use of marijuana, methamphetamines, and other illicit substances in the past 12 months was higher among HIV-positive participants than among HIV-negative/unknown-status participants (28.05% vs 24.99%, 11.48% vs 2.16%, and 27.60% vs 18.22%, respectively; all <italic>P</italic>&lt;.001). Most HIV-negative/unknown-status participants (79.93%, 7248/9068) reported ever having a previous HIV test, and 56.45% (5119/9068) reported undergoing HIV testing in the past 12 months. HIV-positive participants were more likely to report testing and diagnosis of sexually transmitted infections than HIV-negative/unknown-status participants (70.86% vs 40.13% and 24.04% vs 8.97%, respectively; both <italic>P</italic>&lt;.001).</p>
      </abstract>
      <kwd-group>
        <kwd>bisexual</kwd>
        <kwd>gay</kwd>
        <kwd>HIV</kwd>
        <kwd>homosexual</kwd>
        <kwd>internet</kwd>
        <kwd>MSM</kwd>
        <kwd>STD</kwd>
        <kwd>surveillance</kwd>
        <kwd>survey</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>The American Men’s Internet Survey (AMIS) is an annual online behavioral survey of men who have sex with men (MSM), living in the United States. AMIS was developed to produce timely data from large-scale monitoring of behavior trends among MSM recruited online. It was designed to complement the Centers for Disease Control and Prevention’s National HIV Behavioral Surveillance (NHBS) system, which collects data on MSM in major US cities every 3 years through venue-based recruitment [<xref ref-type="bibr" rid="ref1">1</xref>]. The methods and previous AMIS cycle data (AMIS 2013, AMIS 2014, and AMIS 2015) have been previously published [<xref ref-type="bibr" rid="ref2">2</xref>-<xref ref-type="bibr" rid="ref4">4</xref>].</p>
      <p>This supplemental report updates previous information with data collected in AMIS 2016. Methods in the AMIS 2016 did not change from the previously published methods, unless otherwise noted. An in-depth analysis and discussion of multiyear trends for indicators reported herein has been published and includes data for the first four cycles of AMIS (AMIS 2013 through AMIS 2016) [<xref ref-type="bibr" rid="ref5">5</xref>].</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Recruitment and Enrollment</title>
        <p>Similar to the prior year’s recruitment process, AMIS participants were recruited through convenience sampling from a variety of websites using banner advertisements or email blasts to website members (hereafter referred to generically as “ads”). For AMIS 2016, data were collected from September 2016 through February 2017. The survey was not incentivized. Data on the number of clicks on all banner ads were obtained directly from the websites. Men who clicked on the ads were taken directly to the survey website hosted on a secure server administered by SurveyGizmo (Boulder, Colorado). Participants were also recruited by emailing participants from the previous cycle of AMIS (AMIS 2015) who consented to be recontacted for future studies. To be eligible for the survey, participants had to be ≥15 years of age, consider themselves as male, reside in the United States, and report that they either had oral or anal sex with a man at least once in the past or identify as gay or bisexual (hereafter referred to as men who have sex with men [MSM]). Persons who were &lt;15 years of age or refused to provide their age were not asked any other screening questions. MSM who met the eligibility criteria and consented to participate in the study started the online survey immediately. The full questionnaire for AMIS 2016 is presented in <xref ref-type="app" rid="app1">Multimedia Appendix 1</xref>.</p>
        <p>Several data-cleaning steps were performed on the raw dataset of eligible responses to obtain the final analysis dataset. First, deduplication of survey responses was performed in the same manner as in previous AMIS cycles [<xref ref-type="bibr" rid="ref2">2</xref>-<xref ref-type="bibr" rid="ref5">5</xref>]. Briefly, the demographic data for near-complete (&gt;70%) survey responses with nonunique internet protocol addresses were compared, and responses that showed 100% match for all characteristics were considered to be duplicate responses. Only the observation with the highest survey completion was retained. The dataset was then limited to those surveys deemed successful (ie, observations with no missing values for the first question of at least two consecutive sections). Finally, the dataset was restricted to include participants who reported having oral or anal sex in the past 12 months and provided a valid US zone improvement plan (ZIP) code. ZIP codes were validated in same manner as in AMIS 2015 [<xref ref-type="bibr" rid="ref4">4</xref>]. Valid US ZIP codes were those that could be matched to the ZIP code for county crosswalk files created by the US Department of Housing and Urban Development [<xref ref-type="bibr" rid="ref6">6</xref>]. Any ZIP codes that could not be matched to this list were then hand validated by checking against the ZIP code locator tool on the US Postal Service website [<xref ref-type="bibr" rid="ref7">7</xref>]. ZIP codes that could not be found were classified as invalid.</p>
      </sec>
      <sec>
        <title>Measures and Analyses</title>
        <p>For AMIS 2016 analyses, participants were categorized as either AMIS 2015 participants who took the survey again or new participants from the website/app based on target audience and purpose: gay social networking (n=2), gay general interest (n=1), general social networking (n=3), and geospatial social networking (n=2). Recruitment outcomes and demographic characteristics for the AMIS 2015 participants are presented in <xref ref-type="table" rid="table1">Tables 1</xref> and <xref ref-type="table" rid="table2">2</xref>, and thereafter, they are recategorized according to their original source of recruitment. We do not provide the names of the websites/apps to preserve operator and client privacy, particularly when a category has only one operator. Participants whose data were eligible, unduplicated, and successful and who provided consent, reported male-male sex in the past 12 months, and provided a valid US ZIP code were included in analyses of participant characteristics and behavior.</p>
        <p>To facilitate comparisons, the key indicators and analytic approach used in AMIS were designed to mirror those used by the NHBS system [<xref ref-type="bibr" rid="ref8">8</xref>]. Population density was defined in the same manner as in AMIS 2015 and was based on the National Center for Health Statistics Rural-Urban classification scheme for counties [<xref ref-type="bibr" rid="ref9">9</xref>]. The self-reported HIV status was categorized as HIV positive or HIV negative/unknown status, consistent with surveillance reports produced by the NHBS system [<xref ref-type="bibr" rid="ref8">8</xref>]. Three substance use behaviors in the past 12 months were assessed: use of nonprescribed marijuana, use of methamphetamines, and use of any illicit drug other than marijuana or methamphetamines. All other indicators assessed remained unchanged from AMIS 2015 [<xref ref-type="bibr" rid="ref4">4</xref>].</p>
        <p>The analysis methods for AMIS 2016 did not substantively differ from those previously published but are repeated in this report for clarity. Overall, chi-square tests were used to identify whether participant characteristics differed significantly between recruitment sources. Multivariable logistic regression modeling was used to determine significant differences in behaviors based on the self-reported HIV status while controlling for race/ethnicity, age group, NHBS city residency, and type of recruitment website. Metropolitan statistical areas included in the NHBS system in 2016 were Atlanta, GA; Baltimore, MD; Boston, MA; Chicago, IL; Dallas, TX; Denver, CO; Detroit, MI; Houston, TX; Los Angeles, CA; Miami, FL; Nassau-Suffolk, NY; New Orleans, LA, New York City, NY; Newark, NJ; Philadelphia, PA; San Diego, CA; San Francisco, CA; San Juan, PR; Seattle, WA; and Washington, DC. HIV testing behaviors were only examined among those who did not report that they were HIV positive, and these data were presented by participant characteristics. Multivariable logistic regression results are presented as Wald chi-square <italic>P</italic> values to denote an independently significant difference in the behavior for each subgroup compared to a reference group. Statistical significance was set at <italic>P</italic>&lt;.05.</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Recruitment outcomes for the American Men’s Internet Survey, United States, 2016.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="260"/>
            <col width="0"/>
            <col width="120"/>
            <col width="0"/>
            <col width="100"/>
            <col width="0"/>
            <col width="110"/>
            <col width="0"/>
            <col width="130"/>
            <col width="0"/>
            <col width="140"/>
            <col width="0"/>
            <col width="110"/>
            <thead>
              <tr valign="top">
                <td colspan="3">Recruitment outcomes</td>
                <td colspan="2">Total</td>
                <td colspan="2">Gay social networking (n=2)</td>
                <td colspan="2">General gay interest (n=1)</td>
                <td colspan="2">General social networking (n=3)</td>
                <td colspan="2">Geospatial social networking (n=2)</td>
                <td>AMIS<sup>a</sup> 2015 participants</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="3">Clicked ad (N)</td>
                <td colspan="2">147,143</td>
                <td colspan="2">4162</td>
                <td colspan="2">557</td>
                <td colspan="2">58,917</td>
                <td colspan="2">83,507</td>
                <td>Not applicable</td>
              </tr>
              <tr valign="top">
                <td colspan="3">Screened<sup>b</sup>, n (%)</td>
                <td colspan="2">51,876 (35.26)</td>
                <td colspan="2">2877 (69.13)</td>
                <td colspan="2">181 (32.50)</td>
                <td colspan="2">39,281 (66.67)</td>
                <td colspan="2">8137 (9.74)</td>
                <td>1400</td>
              </tr>
              <tr valign="top">
                <td colspan="3"><bold>Ineligible<sup>c</sup>, n (%)</bold></td>
                <td colspan="2">23,173 (44.67)</td>
                <td colspan="2">564 (19.60)</td>
                <td colspan="2">147 (81.22)</td>
                <td colspan="2">19,271 (49.06)</td>
                <td colspan="2">3039 (37.35)</td>
                <td>152 (10.86)</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Not ≥15 years of age<sup>d</sup></td>
                <td colspan="2">16,643 (71.82)</td>
                <td colspan="2">438 (77.66)</td>
                <td colspan="2">91 (61.90)</td>
                <td colspan="2">13,572 (70.43)</td>
                <td colspan="2">2441 (80.32)</td>
                <td colspan="2">101 (66.45)</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Not male<sup>d</sup></td>
                <td colspan="2">19,079 (82.33)</td>
                <td colspan="2">511 (90.60)</td>
                <td colspan="2">94 (63.95)</td>
                <td colspan="2">15,641 (81.16)</td>
                <td colspan="2">2704 (88.98)</td>
                <td colspan="2">129 (84.87)</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Not MSM<sup>e</sup> ever or not identifying as gay/bisexual<sup>d</sup></td>
                <td colspan="2">22,282 (96.16)</td>
                <td colspan="2">549 (97.34)</td>
                <td colspan="2">99 (67.35)</td>
                <td colspan="2">18,721 (97.15)</td>
                <td colspan="2">2790 (91.81)</td>
                <td colspan="2">123 (80.92)</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Nonresident<sup>d</sup></td>
                <td colspan="2">18,989 (81.94)</td>
                <td colspan="2">471 (83.51)</td>
                <td colspan="2">144 (97.96)</td>
                <td colspan="2">15,383 (79.82)</td>
                <td colspan="2">2845 (93.62)</td>
                <td colspan="2">146 (96.05)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">Eligible<sup>c</sup>, n (%)</td>
                <td colspan="2">28,703 (55.33)</td>
                <td colspan="2">2313 (80.40)</td>
                <td colspan="2">34 (18.78)</td>
                <td colspan="2">20,010 (50.94)</td>
                <td colspan="2">5098 (62.65)</td>
                <td>1248 (89.14)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">Consented<sup>f</sup>, n (%)</td>
                <td colspan="2">20,583 (71.71)</td>
                <td colspan="2">1716 (74.19)</td>
                <td colspan="2">28 (82.35)</td>
                <td colspan="2">13,776 (68.85)</td>
                <td colspan="2">3928 (77.05)</td>
                <td>1135 (90.95)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">Unduplicated<sup>g</sup>, n (%)</td>
                <td colspan="2">18,038 (87.64)</td>
                <td colspan="2">1604 (93.47)</td>
                <td colspan="2">23 (82.14)</td>
                <td colspan="2">11,876 (86.21)</td>
                <td colspan="2">3501 (89.13)</td>
                <td>1034 (91.10)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">Success<sup>h</sup>, n (%)</td>
                <td colspan="2">11,636 (64.51)</td>
                <td colspan="2">1242 (77.43)</td>
                <td colspan="2">14 (60.87)</td>
                <td colspan="2">7594 (63.94)</td>
                <td colspan="2">1870 (53.41)</td>
                <td>916 (88.59)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">MSM in past 12 months<sup>i</sup>, n (%)</td>
                <td colspan="2">10,222 (87.85)</td>
                <td colspan="2">1165 (93.80)</td>
                <td colspan="2">13 (92.86)</td>
                <td colspan="2">6443 (84.84)</td>
                <td colspan="2">1756 (93.90)</td>
                <td>845 (92.25)</td>
              </tr>
              <tr valign="top">
                <td colspan="3">Valid ZIP<sup>j</sup> code<sup>k</sup>, n (%)</td>
                <td colspan="2">10,166 (99.45)</td>
                <td colspan="2">1160 (99.57)</td>
                <td colspan="2">13 (100.00)</td>
                <td colspan="2">6401 (99.35)</td>
                <td colspan="2">1750 (99.66)</td>
                <td>842 (99.64)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>AMIS: American Men’s Internet Survey.</p>
            </fn>
            <fn id="table1fn2">
              <p><sup>b</sup>Proportion of total participants who clicked on the ad, including those who started the screening questionnaire.</p>
            </fn>
            <fn id="table1fn3">
              <p><sup>c</sup>Proportion of total participants screened. Participants who did not complete the screening questionnaire were considered ineligible.</p>
            </fn>
            <fn id="table1fn4">
              <p><sup>d</sup>Proportion of total ineligible participants, including those who did not respond to the question.</p>
            </fn>
            <fn id="table1fn5">
              <p><sup>e</sup>MSM: men who have sex with men.</p>
            </fn>
            <fn id="table1fn6">
              <p><sup>f</sup>Proportion of eligible participants.</p>
            </fn>
            <fn id="table1fn7">
              <p><sup>g</sup>Proportion of participants who consented. Deduplication removes participants who were marked as duplicates using the internet protocol address and demographic data matching.</p>
            </fn>
            <fn id="table1fn8">
              <p><sup>h</sup>Proportion of unduplicated participants. Success in deduplication removes participants who did not pass the test for survey completeness.</p>
            </fn>
            <fn id="table1fn9">
              <p><sup>i</sup>Proportion of successes.</p>
            </fn>
            <fn id="table1fn10">
              <p><sup>j</sup>ZIP: zone improvement plan.</p>
            </fn>
            <fn id="table1fn11">
              <p><sup>k</sup>Proportion of men who had sex with men in the past 12 months. Valid US ZIP codes were those that could be matched to the ZIP code for county crosswalk files created by the US Department of Housing and Urban Development. Any ZIP codes that could not be matched to this list were then hand validated by checking against the ZIP code-locator tool on the US Postal Service website. ZIP codes that could not be found were classified as invalid.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Characteristics of men who have sex with men in the American Men's Internet Survey by recruitment type, United States, 2016.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="180"/>
            <col width="120"/>
            <col width="0"/>
            <col width="100"/>
            <col width="0"/>
            <col width="110"/>
            <col width="0"/>
            <col width="130"/>
            <col width="0"/>
            <col width="140"/>
            <col width="0"/>
            <col width="110"/>
            <col width="80"/>
            <thead>
              <tr valign="bottom">
                <td colspan="2">Participant characteristics</td>
                <td colspan="11">Recruitment type</td>
                <td><italic>P</italic> value<sup>b</sup></td>
              </tr>
              <tr valign="top">
                <td colspan="2"><break/></td>
                <td colspan="2">Total</td>
                <td colspan="2">Gay social networking (n=2)</td>
                <td colspan="2">General gay interest (n=1)</td>
                <td colspan="2">General social networking (n=3)</td>
                <td colspan="2">Geospatial social networking (n=2)</td>
                <td>AMIS<sup>a</sup> 2015 participants</td>
                <td><break/></td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="13"><bold>Race/ethnicity, n (%)</bold></td>
                <td>&lt;.001</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Black, non-Hispanic</td>
                <td>879 (8.65)</td>
                <td colspan="2">35 (3.02)</td>
                <td colspan="2">0 (0.00)</td>
                <td colspan="2">664 (10.37)</td>
                <td colspan="2">141 (8.06)</td>
                <td colspan="2">39 (4.63)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Hispanic</td>
                <td>1311 (12.90)</td>
                <td colspan="2">73 (6.29)</td>
                <td colspan="2">2 (15.38)</td>
                <td colspan="2">852 (13.31)</td>
                <td colspan="2">286 (16.34)</td>
                <td colspan="2">98 (11.64)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>White, non-Hispanic</td>
                <td>7073 (69.58)</td>
                <td colspan="2">986 (85.00)</td>
                <td colspan="2">8 (61.54)</td>
                <td colspan="2">4274 (66.77)</td>
                <td colspan="2">1157 (66.11)</td>
                <td colspan="2">648 (76.96)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Other or multiple races</td>
                <td>903 (8.88)</td>
                <td colspan="2">66 (5.69)</td>
                <td colspan="2">3 (23.08)</td>
                <td colspan="2">611 (9.55)</td>
                <td colspan="2">166 (9.49)</td>
                <td colspan="2">57 (6.77)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td colspan="13"><bold>Age (years), n (%)</bold></td>
                <td>&lt;.001</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>15-24</td>
                <td>2718 (26.74)</td>
                <td colspan="2">27 (2.33)</td>
                <td colspan="2">6 (46)</td>
                <td colspan="2">2268 (35.43)</td>
                <td colspan="2">271 (15.49)</td>
                <td colspan="2">146 (17.34)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>25-29</td>
                <td>1693 (16.65)</td>
                <td colspan="2">34 (2.93)</td>
                <td colspan="2">2 (15)</td>
                <td colspan="2">1223 (19.11)</td>
                <td colspan="2">265 (15.14)</td>
                <td colspan="2">169 (20.07)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>30-39</td>
                <td>1414 (13.91)</td>
                <td colspan="2">92 (7.93)</td>
                <td colspan="2">1 (8)</td>
                <td colspan="2">719 (11.23)</td>
                <td colspan="2">455 (26.00)</td>
                <td colspan="2">147 (17.46)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>≥40</td>
                <td>4341 (42.70)</td>
                <td colspan="2">1007 (86.81)</td>
                <td colspan="2">4 (31)</td>
                <td colspan="2">2191 (34.23)</td>
                <td colspan="2">759 (43.37)</td>
                <td colspan="2">380 (45.13)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td colspan="13"><bold>Region, n (%)</bold></td>
                <td>&lt;.001</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Northeast</td>
                <td>1879 (18.48)</td>
                <td colspan="2">235 (20.26)</td>
                <td colspan="2">2 (15.38)</td>
                <td colspan="2">1185 (18.51)</td>
                <td colspan="2">306 (17.49)</td>
                <td colspan="2">151 (17.93)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Midwest</td>
                <td>1988 (19.56)</td>
                <td colspan="2">232 (20.00)</td>
                <td colspan="2">4 (30.77)</td>
                <td colspan="2">1352 (21.12)</td>
                <td colspan="2">233 (13.31)</td>
                <td colspan="2">167 (19.83)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>South</td>
                <td>4055 (39.89)</td>
                <td colspan="2">422 (36.38)</td>
                <td colspan="2">4 (30.77)</td>
                <td colspan="2">2506 (39.15)</td>
                <td colspan="2">800 (45.71)</td>
                <td colspan="2">323 (38.36)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>West</td>
                <td>2240 (22.03)</td>
                <td colspan="2">271 (23.36)</td>
                <td colspan="2">3 (23.08)</td>
                <td colspan="2">1355 (21.17)</td>
                <td colspan="2">410 (23.43)</td>
                <td colspan="2">201 (23.87)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>US-dependent areas</td>
                <td>4 (0.04)</td>
                <td colspan="2">0 (0)</td>
                <td colspan="2">0 (0)</td>
                <td colspan="2">3 (0.05)</td>
                <td colspan="2">1 (0.06)</td>
                <td colspan="2">0 (0)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td colspan="13"><bold>NHBS<sup>c</sup> city resident, n (%)</bold></td>
                <td>&lt;.001</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Yes</td>
                <td>4224 (41.55)</td>
                <td colspan="2">500 (43.10</td>
                <td colspan="2">7 (53.85)</td>
                <td colspan="2">2291 (35.81)</td>
                <td colspan="2">1085 (62.00)</td>
                <td colspan="2">341 (40.50)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>No</td>
                <td>5942 (58.45)</td>
                <td colspan="2">660 (56.90</td>
                <td colspan="2">6 (46.15)</td>
                <td colspan="2">4110 (64.21)</td>
                <td colspan="2">665 (38.02)</td>
                <td colspan="2">501 (59.50)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td colspan="13"><bold>Population density<sup>d</sup>, n (%)</bold></td>
                <td>&lt;.001</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Urban</td>
                <td>4288 (42.18)</td>
                <td colspan="2">436 (37.59)</td>
                <td colspan="2">5 (38.46)</td>
                <td colspan="2">2538 (39.65)</td>
                <td colspan="2">944 (53.94)</td>
                <td colspan="2">365 (43.35)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Suburban</td>
                <td>2200 (21.64)</td>
                <td colspan="2">316 (27.24)</td>
                <td colspan="2">6 (46.15)</td>
                <td colspan="2">1298 (20.28)</td>
                <td colspan="2">409 (23.37)</td>
                <td colspan="2">171 (20.31)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Small/medium metropolitan</td>
                <td>2790 (27.44)</td>
                <td colspan="2">305 (26.29)</td>
                <td colspan="2">1 (7.69)</td>
                <td colspan="2">1929 (30.14)</td>
                <td colspan="2">305 (17.43)</td>
                <td colspan="2">250 (29.69)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Rural</td>
                <td>884 (8.70)</td>
                <td colspan="2">103 (8.88)</td>
                <td colspan="2">1 (7.69)</td>
                <td colspan="2">633 (9.89)</td>
                <td colspan="2">91 (5.20)</td>
                <td colspan="2">56 (6.65)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td colspan="13"><bold>Self-reported HIV status, n (%)</bold></td>
                <td>&lt;.001</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Positive</td>
                <td>1098 (10.80)</td>
                <td colspan="2">125 (10.78)</td>
                <td colspan="2">2 (15.38)</td>
                <td colspan="2">619 (9.67)</td>
                <td colspan="2">263 (15.03)</td>
                <td colspan="2">89 (10.57)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Negative</td>
                <td>7089 (69.73)</td>
                <td colspan="2">828 (71.38)</td>
                <td colspan="2">9 (69.23)</td>
                <td colspan="2">4283 (66.91)</td>
                <td colspan="2">1291 (73.77)</td>
                <td colspan="2">678 (80.52)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Unknown</td>
                <td>1979 (19.47)</td>
                <td colspan="2">207 (17.84)</td>
                <td colspan="2">2 (15.38)</td>
                <td colspan="2">1499 (23.42)</td>
                <td colspan="2">196 (11.20)</td>
                <td colspan="2">75 (8.91)</td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td colspan="2">Total (N)</td>
                <td>10,166</td>
                <td colspan="2">1160</td>
                <td colspan="2">13</td>
                <td colspan="2">6401</td>
                <td colspan="2">1750</td>
                <td colspan="2">842</td>
                <td><break/></td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>AMIS: American Men’s Internet Survey.</p>
            </fn>
            <fn id="table2fn2">
              <p><sup>b</sup>Chi-square test for difference in characteristics between recruitment types.</p>
            </fn>
            <fn id="table2fn3">
              <p><sup>c</sup>NHBS: National HIV Behavioral Surveillance.</p>
            </fn>
            <fn id="table2fn4">
              <p><sup>d</sup>The National Center for Health Statistics urban/rural category could not be assigned for four participants living in US territories.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>AMIS 2016 was performed from September 2016 through February 2017 and resulted in 147,143 persons clicking on the ads and landing on the study’s recruitment page (<xref ref-type="table" rid="table1">Table 1</xref>). Most persons who clicked on the ads were from geospatial networking websites (83,507/147,143; 56.75%). Of the 4513 participants who completed the AMIS 2015 survey and were emailed links to the AMIS 2016 survey, 31.02% (1400) clicked on the link. Just over one-third (35.26%) of all of participants who landed on the study page started the screening process and 55.33% of them were eligible. The most common reason for ineligibility was not ever having male-male sex or not identifying as gay or bisexual. Almost three-quarters (71.71%) of participants who were eligible consented to participate in the survey. A total of 2545 (12.36%) surveys were likely from duplicate participants. Among unduplicated surveys, almost two-thirds (64.51%) were considered successful. Most successful surveys were from men who reported having sex with another man in the past 12 months (87.85%). Almost all these surveys (10,166/10,222; 99.45%) provided a valid US ZIP code. Overall, the completion rate was 6.9%, with an analytical sample consisting of 10,166 surveys from 147,143 clicks.</p>
      <p>Over two-thirds (7073/10,166; 69.58%) of the participants included in this report were non-Hispanic white, and less than half were ≥40 years of age (4341/10,166; 42.70%); the most common region of residence was the South followed by the West (<xref ref-type="table" rid="table2">Table 2</xref>). Participants were recruited from all US states, and there were at least 100 participants from each of the 28 states and the District of Columbia (<xref ref-type="fig" rid="figure1">Figure 1</xref>). About 4 in 10 (4224/10,166; 41.55%) participants resided in an NHBS city and about the same proportion (4288/10,166; 42.18%) lived in an urban county. Overall, 10.80% (1098/10,166) of participants were HIV positive, 69.73% were HIV negative (7089/10,166), and 19.74% (1979/10,166) had an unknown HIV status. All participant characteristics differed significantly based on the recruitment source (<xref ref-type="table" rid="table2">Table 2</xref>).</p>
      <p>Most participants reported having anal sex without a condom with another man in the past 12 months (<xref ref-type="table" rid="table3">Table 3</xref>). Compared to HIV-negative/unknown-status participants, those who were HIV positive were significantly more likely to report anal intercourse without a condom (adjusted odds ratio [aOR]=1.79, 95% CI: 1.53-2.08), including with male partners who were of discordant or unknown status (aOR=2.76, 95% CI: 2.38-3.19). Stratified by the serostatus group, anal intercourse without a condom differed significantly by race/ethnicity (HIV-negative/unknown-status participants only), age group (HIV-negative/unknown-status participants only), and recruitment website (HIV-positive and HIV-negative/unknown-status participants). Anal intercourse without a condom with partners of discordant or unknown HIV status differed significantly by race/ethnicity, age, and recruitment website for both HIV-positive participants and HIV-negative/unknown-status participants.</p>
      <fig id="figure1" position="float">
        <label>Figure 1</label>
        <caption>
          <p>Number of men who have sex with men who participated in the American Men’s Internet Survey by state, 2016.</p>
        </caption>
        <graphic xlink:href="publichealth_v5i1e11313_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
      <table-wrap position="float" id="table3">
        <label>Table 3</label>
        <caption>
          <p>Sexual Behaviors with male partners of men who have sex with men in the American Men's Internet Survey, United States, 2016.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="30"/>
          <col width="30"/>
          <col width="240"/>
          <col width="120"/>
          <col width="170"/>
          <col width="100"/>
          <col width="210"/>
          <col width="100"/>
          <thead>
            <tr valign="top">
              <td colspan="3">Participant characteristics</td>
              <td>Participants (N)</td>
              <td colspan="4">Sexual behaviors with male partners in the past 12 months</td>
            </tr>
            <tr valign="top">
              <td colspan="3"><break/></td>
              <td><break/></td>
              <td colspan="2">Anal intercourse without a condom</td>
              <td colspan="2">Anal intercourse without a condom with a partner of discordant or unknown HIV status</td>
            </tr>
            <tr valign="bottom">
              <td colspan="3"><break/></td>
              <td><break/></td>
              <td>n (%)</td>
              <td><italic>P</italic> value<sup>a</sup></td>
              <td>n (%)</td>
              <td><italic>P</italic> value<sup>a</sup></td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td colspan="3"><bold>HIV positive</bold></td>
              <td>1098</td>
              <td>832 (75.77)</td>
              <td>&lt;.001<sup>b</sup></td>
              <td>365 (33.24)</td>
              <td>&lt;.001<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="7"><bold>Race/ethnicity</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Black, non-Hispanic</td>
              <td>248</td>
              <td>175 (70.56)</td>
              <td>.17</td>
              <td>76 (30.65)</td>
              <td>.70</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Hispanic</td>
              <td>130</td>
              <td>96 (73.85)</td>
              <td>.23</td>
              <td>34 (26.15)</td>
              <td>.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>White, non-Hispanic</td>
              <td>632</td>
              <td>492 (77.85)</td>
              <td>Ref<sup>a</sup></td>
              <td>218 (34.49)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Other or multiple races</td>
              <td>88</td>
              <td>69 (78.41)</td>
              <td>.34</td>
              <td>37 (42.05)</td>
              <td>.05</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="7"><bold>Age (years)</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>15-24</td>
              <td>59</td>
              <td>50 (84.75)</td>
              <td>.37</td>
              <td>21 (35.59)</td>
              <td>.87</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>25-29</td>
              <td>97</td>
              <td>80 (82.47)</td>
              <td>.78</td>
              <td>48 (49.48)</td>
              <td>.008</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>30-39</td>
              <td>186</td>
              <td>159 (85.48)</td>
              <td>.16</td>
              <td>76 (40.86)</td>
              <td>.41</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>≥40</td>
              <td>756</td>
              <td>543 (71.83)</td>
              <td>Ref<sup>a</sup></td>
              <td>220 (29.10)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="7"><bold>NHBS<sup>c</sup></bold> <bold>city resident</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Yes</td>
              <td>568</td>
              <td>429 (75.53)</td>
              <td>.78</td>
              <td>195 (34.33)</td>
              <td>.43</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>No</td>
              <td>530</td>
              <td>403 (76.04)</td>
              <td>Ref<sup>a</sup></td>
              <td>170 (32.08)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="7"><bold>Recruitment type</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Gay social networking</td>
              <td>139</td>
              <td>102 (73.38)</td>
              <td>.45</td>
              <td>58 (41.73)</td>
              <td>.004</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>General gay interest<sup>d</sup></td>
              <td>&lt;5</td>
              <td>N/A<sup>e</sup></td>
              <td>N/A</td>
              <td>N/A</td>
              <td>N/A</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>General social networking</td>
              <td>651</td>
              <td>471 (72.35)</td>
              <td>Ref<sup>a</sup></td>
              <td>193 (29.65)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Geospatial social networking</td>
              <td>303</td>
              <td>255 (84.16)</td>
              <td>.007</td>
              <td>111 (36.63)</td>
              <td>.47</td>
            </tr>
            <tr valign="top">
              <td colspan="3"><bold>HIV negative or unknown status</bold></td>
              <td>9068</td>
              <td>5974 (65.88)</td>
              <td>Ref<sup>a</sup></td>
              <td>1456 (16.06)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="7"><bold>Race/ethnicity</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Black, non-Hispanic</td>
              <td>631</td>
              <td>388 (61.49)</td>
              <td>.002</td>
              <td>116 (18.38)</td>
              <td>.08</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Hispanic</td>
              <td>1181</td>
              <td>833 (70.53)</td>
              <td>&lt;.001</td>
              <td>218 (18.46)</td>
              <td>.12</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>White, non-Hispanic</td>
              <td>6441</td>
              <td>4231 (65.69)</td>
              <td>Ref<sup>a</sup></td>
              <td>1010 (15.68)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Other or multiple races</td>
              <td>815</td>
              <td>522 (64.05)</td>
              <td>.28</td>
              <td>112 (13.74)</td>
              <td>.009</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="7"><bold>Age (years)</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>15-24</td>
              <td>2659</td>
              <td>1694 (63.71)</td>
              <td>&lt;.001</td>
              <td>417 (15.68)</td>
              <td>.87</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>25-29</td>
              <td>1596</td>
              <td>1202 (75.31)</td>
              <td>&lt;.001</td>
              <td>285 (17.86)</td>
              <td>.03</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>30-39</td>
              <td>1228</td>
              <td>892 (72.64)</td>
              <td>.002</td>
              <td>232 (18.89)</td>
              <td>.09</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>≥40</td>
              <td>3585</td>
              <td>2186 (60.98)</td>
              <td>Ref<sup>a</sup></td>
              <td>522 (14.56)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="7"><bold>NHBS<sup>c</sup></bold> <bold>city resident</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Yes</td>
              <td>3656</td>
              <td>2436 (66.63)</td>
              <td>&gt;.99</td>
              <td>630 (17.23)</td>
              <td>.14</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>No</td>
              <td>5412</td>
              <td>3538 (65.37)</td>
              <td>Ref<sup>a</sup></td>
              <td>826 (15.26)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="7"><bold>Recruitment type</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Gay social networking</td>
              <td>1119</td>
              <td>626 (55.94)</td>
              <td>&lt;.001</td>
              <td>210 (18.77)</td>
              <td>.007</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>General gay interest</td>
              <td>73</td>
              <td>50 (68.49)</td>
              <td>.76</td>
              <td>10 (13.70)</td>
              <td>.38</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>General social networking</td>
              <td>6125</td>
              <td>4026 (65.73)</td>
              <td>Ref<sup>a</sup></td>
              <td>911 (14.87)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Geospatial social networking</td>
              <td>1731</td>
              <td>1257 (72.62)</td>
              <td>&lt;.001</td>
              <td>321 (18.54)</td>
              <td>.35</td>
            </tr>
          </tbody>
        </table>
        <table-wrap-foot>
          <fn id="table3fn1">
            <p><sup>a</sup>Wald chi-square from multivariate logistic regression comparing behavior (yes vs no) between a group with specific characteristics and a reference group (Ref).</p>
          </fn>
          <fn id="table3fn2">
            <p><sup>b</sup>Wald chi-square from multivariate logistic regression comparing behavior (yes vs no) among HIV-positive participants and HIV-negative or unknown-serostatus participants. Model controlled for race/ethnicity, age, National HIV Behavioral Surveillance system residency, and recruitment type.</p>
          </fn>
          <fn id="table3fn3">
            <p><sup>C</sup>NHBS: National HIV Behavioral Surveillance.</p>
          </fn>
          <fn id="table3fn4">
            <p><sup>d</sup>To prevent identification, data for groups with less than five participants are not presented.</p>
          </fn>
          <fn id="table3fn5">
            <p><sup>e</sup>N/A: not applicable.</p>
          </fn>
        </table-wrap-foot>
      </table-wrap>
      <p>Over one-quarter (308/1098; 28.05%) of HIV-positive participants reported using marijuana in the past 12 months (<xref ref-type="table" rid="table4">Table 4</xref>). Compared to HIV-negative/unknown-status participants, HIV-positive participants were significantly more likely to report use of marijuana (aOR=1.63, 95% CI: 1.40-1.90), methamphetamines (aOR=5.53, 95% CI: 4.30-7.11), and other illicit substances in the past 12 months (aOR=2.15, 95% CI: 1.84-2.52). Among HIV-positive participants, the use of marijuana did not vary significantly for any participant characteristic, but the use of methamphetamines varied significantly by race/ethnicity, age, and recruitment site. In this group, the use of other illicit substances varied significantly by race/ethnicity, age, residence in an NHBS city, and recruitment site. Use of marijuana, methamphetamines, and other illicit substances differed significantly by race/ethnicity and age among HIV-negative/unknown-status participants. Additionally, the use of marijuana and other illicit substances differed significantly by residence in an NHBS city, and the use of other illicit substances differed significantly by recruitment site among HIV-negative/unknown-status participants.</p>
      <p>HIV testing behaviors were examined among participants who were not HIV positive (<xref ref-type="table" rid="table5">Table 5</xref>). Most participants (7248/9068; 79.93%) were previously tested for HIV infection, and just over half (5119/9068; 56.45%) were tested in the past 12 months. HIV testing behavior, both ever tested and tested in the past 12 months, differed significantly by race/ethnicity, age, residence in an NHBS city, and type of recruitment website.</p>
      <p>Compared to HIV-negative/unknown-status participants, HIV-positive participants were significantly more likely to report testing for sexually transmitted infection (STI) (aOR=3.62, 95% CI: 3.13-4.19) and STI diagnosis (aOR=3.25, 95% CI: 2.74-3.87) in the past 12 months (<xref ref-type="table" rid="table6">Table 6</xref>). The most common STI diagnosis among HIV-positive participants was syphilis (164/1098; 14.94%), followed by gonorrhea (125/1098; 11.38%) and chlamydia (108/1098; 9.84%). Gonorrhea was the most common STI diagnosis among HIV-negative/unknown-status participants (456/9068; 5.03%), followed by chlamydia (412/9068; 4.54%) and syphilis (226/9068; 2.49%). Among HIV-negative/unknown-status participants, STI testing differed significantly by race/ethnicity and age. Among both HIV-positive and HIV-negative/unknown-status participants, STI testing differed significantly by NHBS city residence and type of recruitment website, and STI diagnosis differed significantly by age, NHBS city residence, and type of recruitment website.</p>
      <table-wrap position="float" id="table4">
        <label>Table 4</label>
        <caption>
          <p>Substance use behaviors of men who have sex with men in the American Men's Internet Survey, United States, 2016.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="30"/>
          <col width="30"/>
          <col width="220"/>
          <col width="0"/>
          <col width="120"/>
          <col width="0"/>
          <col width="100"/>
          <col width="0"/>
          <col width="100"/>
          <col width="0"/>
          <col width="100"/>
          <col width="0"/>
          <col width="100"/>
          <col width="0"/>
          <col width="0"/>
          <col width="100"/>
          <col width="0"/>
          <col width="100"/>
          <thead>
            <tr valign="top">
              <td colspan="3">Participant characteristics</td>
              <td colspan="2">Participants (N)</td>
              <td colspan="13">Substance use behaviors in the past 12 months</td>
            </tr>
            <tr valign="top">
              <td colspan="3"><break/></td>
              <td colspan="2"><break/></td>
              <td colspan="4">Used marijuana</td>
              <td colspan="4">Used methamphetamines</td>
              <td colspan="5">Used other substance(s)</td>
            </tr>
            <tr valign="bottom">
              <td colspan="3"><break/></td>
              <td colspan="2"><break/></td>
              <td colspan="2">n (%)</td>
              <td colspan="2"><italic>P</italic> value<sup>a</sup></td>
              <td colspan="2">n (%)</td>
              <td colspan="3"><italic>P</italic> value<sup>a</sup></td>
              <td colspan="2">n (%)</td>
              <td colspan="2"><italic>P</italic> value<sup>a</sup></td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td colspan="3"><bold>HIV positive</bold></td>
              <td colspan="2">1098</td>
              <td colspan="2">308 (28.05)</td>
              <td colspan="2">&lt;.001<sup>b</sup></td>
              <td colspan="2">126 (11.48)</td>
              <td colspan="3">&lt;.001<sup>b</sup></td>
              <td colspan="2">303 (27.60)</td>
              <td colspan="2">&lt;.001<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="17"><bold>Race/ethnicity</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Black, non-Hispanic</td>
              <td colspan="2">248</td>
              <td colspan="2">66 (26.61)</td>
              <td colspan="2">.52</td>
              <td colspan="2">16 (6.45)</td>
              <td colspan="3">.02</td>
              <td colspan="2">52 (20.97)</td>
              <td>.04</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Hispanic</td>
              <td colspan="2">130</td>
              <td colspan="2">40 (30.77)</td>
              <td colspan="2">.98</td>
              <td colspan="2">22 (16.92)</td>
              <td colspan="3">.12</td>
              <td colspan="2">44 (33.85)</td>
              <td>.21</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">White, non-Hispanic</td>
              <td colspan="2">632</td>
              <td colspan="2">176 (27.85)</td>
              <td colspan="2">Ref<sup>a</sup></td>
              <td colspan="2">75 (11.87)</td>
              <td colspan="3">Ref<sup>a</sup></td>
              <td colspan="2">183 (28.96)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Other or multiple races</td>
              <td colspan="2">88</td>
              <td colspan="2">26 (29.55)</td>
              <td colspan="2">.96</td>
              <td colspan="2">13 (14.77)</td>
              <td colspan="3">.45</td>
              <td colspan="2">24 (27.27)</td>
              <td>.64</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="17"><bold>Age (years)</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">15-24</td>
              <td colspan="2">59</td>
              <td colspan="2">22 (37.29)</td>
              <td colspan="2">.29</td>
              <td colspan="2">5 (8.47)</td>
              <td colspan="3">.51</td>
              <td colspan="2">21 (35.59)</td>
              <td>.60</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">25-29</td>
              <td colspan="2">97</td>
              <td colspan="2">33 (34.02)</td>
              <td colspan="2">.80</td>
              <td colspan="2">10 (10.31)</td>
              <td colspan="3">.72</td>
              <td colspan="2">41 (42.27)</td>
              <td>.03</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">30-39</td>
              <td colspan="2">186</td>
              <td colspan="2">71 (38.17)</td>
              <td colspan="2">.18</td>
              <td colspan="2">33 (17.74)</td>
              <td colspan="3">.03</td>
              <td colspan="2">65 (34.95)</td>
              <td>.96</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">≥40</td>
              <td colspan="2">756</td>
              <td colspan="2">182 (24.07)</td>
              <td colspan="2">Ref<sup>a</sup></td>
              <td colspan="2">78 (10.32)</td>
              <td colspan="3">Ref<sup>a</sup></td>
              <td colspan="2">176 (23.28)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="17"><bold>NHBS<sup>c</sup></bold> <bold>city resident</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Yes</td>
              <td colspan="2">568</td>
              <td colspan="2">174 (30.63)</td>
              <td colspan="2">.10</td>
              <td colspan="2">78 (13.73)</td>
              <td colspan="3">.11</td>
              <td colspan="2">175 (30.81)</td>
              <td>.04</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">No</td>
              <td colspan="2">530</td>
              <td colspan="2">134 (25.28)</td>
              <td colspan="2">Ref<sup>a</sup></td>
              <td colspan="2">48 (9.06)</td>
              <td colspan="3">Ref<sup>a</sup></td>
              <td colspan="2">128 (24.15)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="17"><bold>Recruitment type</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Gay social networking</td>
              <td colspan="2">139</td>
              <td colspan="2">36 (25.90)</td>
              <td colspan="2">.98</td>
              <td colspan="2">17 (12.23)</td>
              <td colspan="3">.93</td>
              <td colspan="2">34 (24.46)</td>
              <td>.56</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">General gay interest<sup>d</sup></td>
              <td colspan="2">&lt;5</td>
              <td colspan="2">N/A<sup>e</sup></td>
              <td colspan="2">N/A</td>
              <td colspan="2">N/A</td>
              <td colspan="3">N/A</td>
              <td colspan="2">N/A</td>
              <td>N/A</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">General social networking</td>
              <td colspan="2">651</td>
              <td colspan="2">170 (26.11)</td>
              <td colspan="2">Ref<sup>a</sup></td>
              <td colspan="2">50 (7.68)</td>
              <td colspan="3">Ref<sup>a</sup></td>
              <td colspan="2">153 (23.50)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Geospatial social networking</td>
              <td colspan="2">303</td>
              <td colspan="2">100 (33.00)</td>
              <td colspan="2">.35</td>
              <td colspan="2">57 (18.81)</td>
              <td colspan="3">.007</td>
              <td colspan="2">113 (37.29)</td>
              <td>.01</td>
            </tr>
            <tr valign="top">
              <td colspan="3"><bold>HIV negative or unknown status</bold></td>
              <td colspan="2">9068</td>
              <td colspan="2">2266 (24.99)</td>
              <td colspan="2">Ref<sup>a</sup></td>
              <td colspan="2">196 (2.16)</td>
              <td colspan="3">Ref<sup>a</sup></td>
              <td colspan="2">1652 (18.22)</td>
              <td colspan="2">Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="17"><bold>Race/ethnicity</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Black, non-Hispanic</td>
              <td colspan="2">631</td>
              <td colspan="2">126 (19.97)</td>
              <td colspan="2">.006</td>
              <td colspan="2">8 (1.27)</td>
              <td colspan="3">.049</td>
              <td colspan="2">86 (13.63)</td>
              <td>.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Hispanic</td>
              <td colspan="2">1181</td>
              <td colspan="2">344 (29.13)</td>
              <td colspan="2">.04</td>
              <td colspan="2">37 (3.13)</td>
              <td colspan="3">.03</td>
              <td colspan="2">275 (23.29)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">White, non-Hispanic</td>
              <td colspan="2">6441</td>
              <td colspan="2">1597 (24.79)</td>
              <td colspan="2">Ref<sup>a</sup></td>
              <td colspan="2">128 (1.99)</td>
              <td colspan="3">Ref<sup>a</sup></td>
              <td colspan="2">1152 (17.89)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Other or multiple races</td>
              <td colspan="2">815</td>
              <td colspan="2">199 (24.42)</td>
              <td colspan="2">.33</td>
              <td colspan="2">23 (2.82)</td>
              <td colspan="3">.12</td>
              <td colspan="2">139 (17.06)</td>
              <td>.27</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="17"><bold>Age (years)</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">15-24</td>
              <td colspan="2">2659</td>
              <td colspan="2">886 (33.32)</td>
              <td colspan="2">&lt;.001</td>
              <td colspan="2">37 (1.39)</td>
              <td colspan="3">.03</td>
              <td colspan="2">548 (20.61)</td>
              <td>.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">25-29</td>
              <td colspan="2">1596</td>
              <td colspan="2">500 (31.33)</td>
              <td colspan="2">&lt;.001</td>
              <td colspan="2">35 (2.19)</td>
              <td colspan="3">.60</td>
              <td colspan="2">388 (24.31)</td>
              <td>.18</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">30-39</td>
              <td colspan="2">1228</td>
              <td colspan="2">322 (26.22)</td>
              <td colspan="2">.74</td>
              <td colspan="2">42 (3.42)</td>
              <td colspan="3">.04</td>
              <td colspan="2">270 (21.99)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">≥40</td>
              <td colspan="2">3585</td>
              <td colspan="2">558 (15.56)</td>
              <td colspan="2">Ref<sup>a</sup></td>
              <td colspan="2">82 (2.29)</td>
              <td colspan="3">Ref<sup>a</sup></td>
              <td colspan="2">446 (12.44)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="17"><bold>NHBS<sup>c</sup></bold> <bold>city resident</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Yes</td>
              <td colspan="2">3656</td>
              <td colspan="2">1024 (28.01)</td>
              <td colspan="2">&lt;.001</td>
              <td colspan="2">94 (2.57)</td>
              <td colspan="3">.48</td>
              <td colspan="2">779 (21.31)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">No</td>
              <td colspan="2">5412</td>
              <td colspan="2">1242 (22.95)</td>
              <td colspan="2">Ref<sup>a</sup></td>
              <td colspan="2">102 (1.88)</td>
              <td colspan="3">Ref<sup>a</sup></td>
              <td colspan="2">873 (16.13)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="17"><bold>Recruitment type</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Gay social networking</td>
              <td colspan="2">1119</td>
              <td colspan="2">201 (17.96)</td>
              <td colspan="2">.71</td>
              <td colspan="2">37 (3.31)</td>
              <td colspan="3">.13</td>
              <td colspan="2">150 (13.40)</td>
              <td>.68</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">General gay interest</td>
              <td colspan="2">73</td>
              <td colspan="2">16 (21.92)</td>
              <td colspan="2">.55</td>
              <td colspan="2">1 (6.25)</td>
              <td colspan="3">.48</td>
              <td colspan="2">12 (16.44)</td>
              <td>.52</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">General social networking</td>
              <td colspan="2">6125</td>
              <td colspan="2">1572 (25.67)</td>
              <td colspan="2">Ref<sup>a</sup></td>
              <td colspan="2">90 (1.47)</td>
              <td colspan="3">Ref<sup>a</sup></td>
              <td colspan="2">1068 (17.44)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td colspan="2">Geospatial social networking</td>
              <td colspan="2">1731</td>
              <td colspan="2">473 (27.33)</td>
              <td colspan="2">.11</td>
              <td colspan="2">68 (3.93)</td>
              <td colspan="3">.08</td>
              <td colspan="2">419 (24.21)</td>
              <td>&lt;.001</td>
            </tr>
          </tbody>
        </table>
        <table-wrap-foot>
          <fn id="table4fn1">
            <p><sup>a</sup>Wald chi-square from multivariable logistic regression comparing behavior (yes vs no) between groups with specific characteristics and a reference (Ref) group.</p>
          </fn>
          <fn id="table4fn2">
            <p><sup>b</sup>Wald chi-square from multivariable logistic regression comparing behavior (yes vs no) between HIV-positive participants and HIV-negative or unknown-serostatus participants. Model controlled for race/ethnicity, age, National HIV Behavioral Surveillance system residency, and website type.</p>
          </fn>
          <fn id="table4fn3">
            <p><sup>c</sup>NHBS: National HIV Behavioral Surveillance.</p>
          </fn>
          <fn id="table4fn4">
            <p><sup>d</sup>To prevent identification, data for groups with less than five participants are not presented.</p>
          </fn>
          <fn id="table4fn5">
            <p><sup>e</sup>N/A: not applicable.</p>
          </fn>
        </table-wrap-foot>
      </table-wrap>
      <table-wrap position="float" id="table5">
        <label>Table 5</label>
        <caption>
          <p>HIV testing behaviors of HIV-negative or unknown-status men who have sex with men in the American Men's Internet Survey, United States, 2016.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="30"/>
          <col width="270"/>
          <col width="120"/>
          <col width="170"/>
          <col width="100"/>
          <col width="210"/>
          <col width="100"/>
          <thead>
            <tr valign="top">
              <td colspan="2">Participant characteristics</td>
              <td>Participants (N)</td>
              <td colspan="4">HIV testing behaviors</td>
            </tr>
            <tr valign="top">
              <td colspan="2"><break/></td>
              <td><break/></td>
              <td colspan="2">HIV tested ever</td>
              <td colspan="2">HIV tested in past 12 months</td>
            </tr>
            <tr valign="bottom">
              <td colspan="2"><break/></td>
              <td><break/></td>
              <td>n (%)</td>
              <td><italic>P</italic> value<sup>a</sup></td>
              <td>n (%)</td>
              <td><italic>P</italic> value<sup>a</sup></td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td colspan="7"><bold>Race/ethnicity</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>Black, non-Hispanic</td>
              <td>631</td>
              <td>563 (89.22)</td>
              <td>&lt;.001</td>
              <td>440 (69.73)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>Hispanic</td>
              <td>1181</td>
              <td>916 (77.56)</td>
              <td>.09</td>
              <td>710 (60.12)</td>
              <td>.68</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>White, non-Hispanic</td>
              <td>6441</td>
              <td>5134 (79.71)</td>
              <td>Ref<sup>a</sup></td>
              <td>3512 (54.53)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>Other or multiple races</td>
              <td>815</td>
              <td>635 (77.91)</td>
              <td>.30</td>
              <td>457 (56.07)</td>
              <td>.02</td>
            </tr>
            <tr valign="top">
              <td colspan="7"><bold>Age (years)</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>15-24</td>
              <td>2659</td>
              <td>1521 (57.20)</td>
              <td>&lt;.001</td>
              <td>1207 (45.39)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>25-29</td>
              <td>1596</td>
              <td>1393 (87.28)</td>
              <td>.004</td>
              <td>1040 (65.16)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>30-39</td>
              <td>1228</td>
              <td>1129 (91.94)</td>
              <td>&lt;.001</td>
              <td>829 (67.51)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>≥40</td>
              <td>3585</td>
              <td>3205 (89.40)</td>
              <td>Ref<sup>a</sup></td>
              <td>2043 (56.99)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td colspan="7"><bold>NHBS<sup>b</sup></bold> <bold>city resident</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>Yes</td>
              <td>3656</td>
              <td>3112 (85.12)</td>
              <td>&lt;.001</td>
              <td>2356 (64.44)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>No</td>
              <td>5412</td>
              <td>4136 (76.42)</td>
              <td>Ref<sup>a</sup></td>
              <td>2763 (51.05)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td colspan="2"><bold>Recruitment type</bold></td>
              <td>1119</td>
              <td>926 (82.75)</td>
              <td><break/></td>
              <td><break/></td>
              <td><break/></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>Gay social networking</td>
              <td>73</td>
              <td>66 (90.41)</td>
              <td>&lt;.001</td>
              <td>577 (51.56)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>General gay interest</td>
              <td>6125</td>
              <td>4676 (76.34)</td>
              <td>.18</td>
              <td>44 (60.27)</td>
              <td>.93</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>General social networking</td>
              <td>1731</td>
              <td>1563 (90.29)</td>
              <td>Ref<sup>a</sup></td>
              <td>3193 (52.13)</td>
              <td>Ref<sup>a</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td>Geospatial social networking</td>
              <td>1119</td>
              <td>926 (82.75)</td>
              <td>&lt;.001</td>
              <td>1292 (74.64)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td colspan="2">Total</td>
              <td>9068</td>
              <td>7248 (79.93)</td>
              <td><break/></td>
              <td>5119 (56.45)</td>
              <td><break/></td>
            </tr>
          </tbody>
        </table>
        <table-wrap-foot>
          <fn id="table5fn1">
            <p><sup>a</sup>Wald chi-square from multivariable logistic regression comparing behavior (yes vs no) between groups with specific characteristics and a reference (Ref) group.</p>
          </fn>
          <fn id="table5fn2">
            <p><sup>b</sup>NHBS: National HIV Behavioral Surveillance.</p>
          </fn>
        </table-wrap-foot>
      </table-wrap>
      <table-wrap position="float" id="table6">
        <label>Table 6</label>
        <caption>
          <p>Sexually transmitted infection testing and diagnosis of men who have sex with men participants in the American Men's Internet Survey, United States, 2016.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="30"/>
          <col width="30"/>
          <col width="240"/>
          <col width="120"/>
          <col width="170"/>
          <col width="100"/>
          <col width="0"/>
          <col width="210"/>
          <col width="100"/>
          <thead>
            <tr valign="bottom">
              <td colspan="3">Participant characteristics</td>
              <td>Participants (N)</td>
              <td colspan="5">STI<sup>a</sup> history in the past 12 months</td>
            </tr>
            <tr valign="top">
              <td colspan="3"><break/></td>
              <td><break/></td>
              <td colspan="2">Tested for any STI</td>
              <td colspan="3">Diagnosed with any STI</td>
            </tr>
            <tr valign="bottom">
              <td colspan="3"><break/></td>
              <td><break/></td>
              <td>n (%)</td>
              <td colspan="2"><italic>P</italic> value<sup>b</sup></td>
              <td>n (%)</td>
              <td><italic>P</italic> value<sup>b</sup></td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td colspan="3"><bold>HIV positive</bold></td>
              <td>1098</td>
              <td>778 (70.86)</td>
              <td colspan="2">&lt;.001<sup>c</sup></td>
              <td>264 (24.04)</td>
              <td>&lt;.001<sup>c</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="8"><bold>Race/ethnicity</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Black, non-Hispanic</td>
              <td>248</td>
              <td>178 (71.77)</td>
              <td colspan="2">.40</td>
              <td>67 (27.02)</td>
              <td>.30</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Hispanic</td>
              <td>130</td>
              <td>105 (80.77)</td>
              <td colspan="2">.24</td>
              <td>39 (30.00)</td>
              <td>.82</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>White, non-Hispanic</td>
              <td>632</td>
              <td>426 (67.41)</td>
              <td colspan="2">Ref<sup>b</sup></td>
              <td>134 (21.20)</td>
              <td>Ref<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Other or multiple races</td>
              <td>88</td>
              <td>69 (78.41)</td>
              <td colspan="2">.40</td>
              <td>24 (27.27)</td>
              <td>.94</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="8"><bold>Age (years)</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>15-24</td>
              <td>59</td>
              <td>47 (79.66)</td>
              <td colspan="2">.52</td>
              <td>16 (27.12)</td>
              <td>.90</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>25-29</td>
              <td>97</td>
              <td>80 (82.47)</td>
              <td colspan="2">.28</td>
              <td>37 (38.14)</td>
              <td>.03</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>30-39</td>
              <td>186</td>
              <td>152 (81.72)</td>
              <td colspan="2">.45</td>
              <td>67 (36.02)</td>
              <td>.26</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>≥40</td>
              <td>756</td>
              <td>499 (66.01)</td>
              <td colspan="2">Ref<sup>b</sup></td>
              <td>144 (19.05)</td>
              <td>Ref<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="8"><bold>NHBS<sup>d</sup></bold> <bold>city resident</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Yes</td>
              <td>568</td>
              <td>426 (75.00)</td>
              <td colspan="2">.03</td>
              <td>166 (29.23)</td>
              <td>.004</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>No</td>
              <td>530</td>
              <td>352 (66.42)</td>
              <td colspan="2">Ref<sup>b</sup></td>
              <td>98 (18.49)</td>
              <td>Ref<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="8"><bold>Recruitment website type</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Gay social networking</td>
              <td>139</td>
              <td>92 (66.19)</td>
              <td colspan="2">.44</td>
              <td>29 (20.86)</td>
              <td>.90</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>General gay interest<sup>e</sup></td>
              <td>&lt;5</td>
              <td>N/A<sup>f</sup></td>
              <td colspan="2">N/A</td>
              <td>N/A</td>
              <td>N/A</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>General social networking</td>
              <td>651</td>
              <td>439 (67.43)</td>
              <td colspan="2">Ref<sup>b</sup></td>
              <td>124 (19.05)</td>
              <td>Ref<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Geospatial social networking</td>
              <td>303</td>
              <td>242 (79.87)</td>
              <td colspan="2">.004</td>
              <td>110 (36.30)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td colspan="3"><bold>HIV negative or unknown status</bold></td>
              <td>9068</td>
              <td>3639 (40.13)</td>
              <td colspan="2">Ref<sup>b</sup></td>
              <td>813 (8.97)</td>
              <td>Ref<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="8"><bold>Race/ethnicity</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Black, non-Hispanic</td>
              <td>631</td>
              <td>313 (49.60)</td>
              <td colspan="2">.01</td>
              <td>77 (12.20)</td>
              <td>.20</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Hispanic</td>
              <td>1181</td>
              <td>566 (47.93)</td>
              <td colspan="2">.16</td>
              <td>154 (13.04)</td>
              <td>.08</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>White, non-Hispanic</td>
              <td>6441</td>
              <td>2409 (37.40)</td>
              <td colspan="2">Ref<sup>b</sup></td>
              <td>498 (7.73)</td>
              <td>Ref<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Other or multiple races</td>
              <td>815</td>
              <td>351 (43.07)</td>
              <td colspan="2">.35</td>
              <td>84 (10.31)</td>
              <td>.59</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="8"><bold>Age (years)</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>15-24</td>
              <td>2659</td>
              <td>935 (35.16)</td>
              <td colspan="2">&lt;.001</td>
              <td>216 (8.12)</td>
              <td>.21</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>25-29</td>
              <td>1596</td>
              <td>848 (53.13)</td>
              <td colspan="2">&lt;.001</td>
              <td>213 (13.35)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>30-39</td>
              <td>1228</td>
              <td>617 (50.24)</td>
              <td colspan="2">.01</td>
              <td>155 (12.62)</td>
              <td>.23</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>≥40</td>
              <td>3585</td>
              <td>1239 (34.56)</td>
              <td colspan="2">Ref<sup>b</sup></td>
              <td>229 (6.39)</td>
              <td>Ref<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="8"><bold>NHBS<sup>d</sup></bold> <bold>city resident</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Yes</td>
              <td>3656</td>
              <td>1762 (48.19)</td>
              <td colspan="2">&lt;.001</td>
              <td>438 (11.98)</td>
              <td>&lt;.001</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>No</td>
              <td>5412</td>
              <td>1877 (34.68)</td>
              <td colspan="2">Ref<sup>b</sup></td>
              <td>375 (6.93)</td>
              <td>Ref<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td colspan="8"><bold>Recruitment website type</bold></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Gay social networking</td>
              <td>1119</td>
              <td>338 (30.21)</td>
              <td colspan="2">&lt;.001</td>
              <td>55 (4.92)</td>
              <td>.05</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>General gay interest</td>
              <td>73</td>
              <td>27 (36.99)</td>
              <td colspan="2">.35</td>
              <td>5 (6.85)</td>
              <td>.53</td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>General social networking</td>
              <td>6125</td>
              <td>2264 (36.96)</td>
              <td colspan="2">Ref<sup>b</sup></td>
              <td>469 (7.66)</td>
              <td>Ref<sup>b</sup></td>
            </tr>
            <tr valign="top">
              <td><break/></td>
              <td><break/></td>
              <td>Geospatial social networking</td>
              <td>1731</td>
              <td>1001 (57.83)</td>
              <td colspan="2">&lt;.001</td>
              <td>284 (16.41)</td>
              <td>&lt;.001</td>
            </tr>
          </tbody>
        </table>
        <table-wrap-foot>
          <fn id="table6fn1">
            <p><sup>a</sup>STI: sexually transmitted infection and includes chlamydia, gonorrhea, and syphilis.</p>
          </fn>
          <fn id="table6fn2">
            <p><sup>b</sup>Wald chi-square from multivariable logistic regression comparing behavior (yes vs no) between groups with specific characteristics and a reference (Ref) group.</p>
          </fn>
          <fn id="table6fn3">
            <p><sup>c</sup>Wald chi-square from multivariable logistic regression comparing behavior (yes vs no) between HIV-positive participants and HIV-negative or unknown-serostatus participants. Model controlled for race/ethnicity, age, National HIV Behavioral Surveillance system residency, and website type.</p>
          </fn>
          <fn id="table6fn4">
            <p><sup>d</sup>NHBS: National HIV Behavioral Surveillance.</p>
          </fn>
          <fn id="table6fn5">
            <p><sup>e</sup>To prevent identification, data for groups with less than five participants are not presented.</p>
          </fn>
          <fn id="table6fn6">
            <p><sup>f</sup>N/A: not applicable.</p>
          </fn>
        </table-wrap-foot>
      </table-wrap>
    </sec>
  </body>
  <back>
    <app-group>
      <app id="app1">
        <title>Multimedia Appendix 1</title>
        <p>American Men’s Internet Survey 2016 questionnaire.</p>
        <media xlink:href="publichealth_v5i1e11313_app1.pdf" xlink:title="PDF File (Adobe PDF File), 450KB"/>
      </app>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">aOR</term>
          <def>
            <p>adjusted odds ratio</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">AMIS</term>
          <def>
            <p>American Men’s Internet Survey</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">MSM</term>
          <def>
            <p>men who have sex with men</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">NHBS</term>
          <def>
            <p>National HIV Behavioral Surveillance</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">STI</term>
          <def>
            <p>sexually transmitted infection</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">ZIP</term>
          <def>
            <p>zone improvement plan</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The study was funded by a grant from the MAC AIDS Fund and by the National Institutes of Health [P30AI050409]–the Emory Center for AIDS Research.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>TS and PS are members of the Editorial Board of JMIR Public Health and Surveillance. However, they had no involvement in the editorial decision for this manuscript. It was reviewed and handled by an independent editor.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Finlayson</surname>
            <given-names>TJ</given-names>
          </name>
          <name name-style="western">
            <surname>Le</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Smith</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Bowles</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Cribbin</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Miles</surname>
            <given-names>I</given-names>
          </name>
          <name name-style="western">
            <surname>Oster</surname>
            <given-names>AM</given-names>
          </name>
          <name name-style="western">
            <surname>Martin</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Edwards</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Dinenno</surname>
            <given-names>E</given-names>
          </name>
          <collab>Centers for Disease ControlPrevention (CDC)</collab>
        </person-group>
        <article-title>HIV risk, prevention, and testing behaviors among men who have sex with men--National HIV Behavioral Surveillance System, 21 U.S. cities, United States, 2008</article-title>
        <source>MMWR Surveill Summ</source>  
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