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    <front>
        <journal-meta>
            <journal-id journal-id-type="publisher-id">JPH</journal-id>
            <journal-id journal-id-type="nlm-ta">JMIR Public Health Surveill</journal-id>
            <journal-title>JMIR Public Health and Surveillance</journal-title>
            <issn pub-type="epub">2369-2960</issn>
            <publisher>
                <publisher-name>JMIR Publications</publisher-name>
                <publisher-loc>Toronto, Canada</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="publisher-id">v1i2e13</article-id>
            <article-id pub-id-type="pmid">27227131</article-id>
            <article-id pub-id-type="doi">10.2196/publichealth.4360</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Original Paper</subject>
                </subj-group>
                <subj-group subj-group-type="article-type">
                    <subject>Original Paper</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>Patient-Reported Outcomes and Total Health Care Expenditure in Prediction of Patient Satisfaction: Results From a National Study</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="editor">
                    <name>
                        <surname>Eysenbach</surname>
                        <given-names>Gunther</given-names>
                    </name>
                </contrib>
            </contrib-group>
            <contrib-group>
                <contrib contrib-type="reviewer">
                    <name>
                        <surname>Papastavrou</surname>
                        <given-names>Evridiki</given-names>
                    </name>
                </contrib>
                <contrib contrib-type="reviewer">
                    <name>
                        <surname>Rahmqvist</surname>
                        <given-names>Mikael</given-names>
                    </name>
                </contrib>
            </contrib-group>
            <contrib-group>
                <contrib contrib-type="author" id="contrib1" corresp="yes">
                    <name name-style="western">
                        <surname>Hung</surname>
                        <given-names>Man</given-names>
                    </name>
                    <degrees>PhD</degrees>
                    <xref rid="aff1" ref-type="aff">1</xref>
                    <address>
                        <institution>Department of Orthopaedics</institution>
                        <institution>University of Utah</institution>
                        <addr-line>590 Wakara Way</addr-line>
                        <addr-line>Salt Lake City, UT, 84108</addr-line>
                        <country>United States</country>
                        <phone>1 801 587 5372</phone>
                        <fax>1 801 587 5411</fax>
                        <email>man.hung@hsc.utah.edu</email>
                    </address>
                    <xref rid="aff2" ref-type="aff">2</xref>
                    <xref rid="aff3" ref-type="aff">3</xref>
                    <xref rid="aff4" ref-type="aff">4</xref>
                    <xref rid="aff5" ref-type="aff">5</xref>
                    <xref rid="aff6" ref-type="aff">6</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0003-2827-3740</ext-link>
                </contrib>
                <contrib contrib-type="author" id="contrib2">
                    <name name-style="western">
                        <surname>Zhang</surname>
                        <given-names>Weiping</given-names>
                    </name>
                    <degrees>PhD</degrees>
                    <xref rid="aff4" ref-type="aff">4</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-8917-2084</ext-link>
                </contrib>
                <contrib contrib-type="author" id="contrib3">
                    <name name-style="western">
                        <surname>Chen</surname>
                        <given-names>Wei</given-names>
                    </name>
                    <degrees>PhD</degrees>
                    <xref rid="aff5" ref-type="aff">5</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-2907-6354</ext-link>
                </contrib>
                <contrib contrib-type="author" id="contrib4">
                    <name name-style="western">
                        <surname>Bounsanga</surname>
                        <given-names>Jerry</given-names>
                    </name>
                    <xref rid="aff1" ref-type="aff">1</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-6852-4650</ext-link>
                </contrib>
                <contrib contrib-type="author" id="contrib5">
                    <name name-style="western">
                        <surname>Cheng</surname>
                        <given-names>Christine</given-names>
                    </name>
                    <xref rid="aff1" ref-type="aff">1</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-5186-8155</ext-link>
                </contrib>
                <contrib contrib-type="author" id="contrib6">
                    <name name-style="western">
                        <surname>Franklin</surname>
                        <given-names>Jeremy D</given-names>
                    </name>
                    <degrees>PhD</degrees>
                    <xref rid="aff6" ref-type="aff">6</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0003-4613-3629</ext-link>
                </contrib>
                <contrib contrib-type="author" id="contrib7">
                    <name name-style="western">
                        <surname>Crum</surname>
                        <given-names>Anthony B</given-names>
                    </name>
                    <degrees>BS</degrees>
                    <xref rid="aff1" ref-type="aff">1</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-4832-2530</ext-link>
                </contrib>
                <contrib contrib-type="author" id="contrib8">
                    <name name-style="western">
                        <surname>Voss</surname>
                        <given-names>Maren W</given-names>
                    </name>
                    <degrees>MS</degrees>
                    <xref rid="aff1" ref-type="aff">1</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-9054-7389</ext-link>
                </contrib>
                <contrib contrib-type="author" id="contrib9">
                    <name name-style="western">
                        <surname>Hon</surname>
                        <given-names>Shirley D</given-names>
                    </name>
                    <xref rid="aff1" ref-type="aff">1</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-0150-2753</ext-link>
                </contrib>
            </contrib-group>
            <aff id="aff1">
                <sup>1</sup>
                <institution>Department of Orthopaedics</institution>
                <institution>University of Utah</institution>
                <addr-line>Salt Lake City, UT</addr-line>
                <country>United States</country>
            </aff>
            <aff id="aff2">
                <sup>2</sup>
                <institution>Division of Public Health</institution>
                <institution>University of Utah</institution>
                <addr-line>Salt Lake City, UT</addr-line>
                <country>United States</country>
            </aff>
            <aff id="aff3">
                <sup>3</sup>
                <institution>School of Business</institution>
                <institution>University of Utah</institution>
                <addr-line>Salt Lake City, UT</addr-line>
                <country>United States</country>
            </aff>
            <aff id="aff4">
                <sup>4</sup>
                <institution>School of Medicine</institution>
                <institution>University of Utah</institution>
                <addr-line>Salt Lake City, UT</addr-line>
                <country>United States</country>
            </aff>
            <aff id="aff5">
                <sup>5</sup>
                <institution>Division of Epidemiology</institution>
                <institution>University of Utah</institution>
                <addr-line>Salt Lake City, UT</addr-line>
                <country>United States</country>
            </aff>
            <aff id="aff6">
                <sup>6</sup>
                <institution>College of Education</institution>
                <institution>University of Utah</institution>
                <addr-line>Salt Lake City, UT</addr-line>
                <country>United States</country>
            </aff>
            <author-notes>
                <corresp>Corresponding Author: Man Hung <email>man.hung@hsc.utah.edu</email>
                </corresp>
            </author-notes>
            <pub-date pub-type="collection">
                <season>Jul-Dec</season>
                <year>2015</year>
            </pub-date>
            <pub-date pub-type="epub">
                <day>23</day>
                <month>09</month>
                <year>2015</year>
            </pub-date>
            <volume>1</volume>
            <issue>2</issue>
            <elocation-id>e13</elocation-id>
            <!--history from ojs - api-xml-->
            <history>
                <date date-type="received">
                    <day>19</day>
                    <month>2</month>
                    <year>2015</year>
                </date>
                <date date-type="rev-request">
                    <day>7</day>
                    <month>4</month>
                    <year>2015</year>
                </date>
                <date date-type="rev-recd">
                    <day>12</day>
                    <month>7</month>
                    <year>2015</year>
                </date>
                <date date-type="accepted">
                    <day>17</day>
                    <month>8</month>
                    <year>2015</year>
                </date>
            </history>
            <!--(c) the authors - correct author names and publication date here if necessary. Date in form ', dd.mm.yyyy' after jmir.org-->
            <copyright-statement>&#169;Man Hung, Weiping Zhang, Wei Chen, Jerry Bounsanga, Christine Cheng, Jeremy D Franklin, Anthony B Crum, Maren W Voss, Shirley D Hon. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 23.09.2015. </copyright-statement>
            <copyright-year>2015</copyright-year>
            <license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0/">
                <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Public Health and Surveillance, is properly cited. The complete bibliographic information, a link to the original publication on http://publichealth.jmir.org, as well as this copyright and license information must be included.</p>
            </license>
            <self-uri xlink:href="http://publichealth.jmir.org/2015/2/e13/" xlink:type="simple" />
            <abstract>
                <sec sec-type="background">
                    <title>Background</title>
                    <p>Health care quality is often linked to patient satisfaction. Yet, there is a lack of national studies examining the relationship between patient satisfaction, patient-reported outcomes, and medical expenditure.</p>
                </sec>
                <sec sec-type="objective">
                    <title>Objective</title>
                    <p>The aim of this study is to examine the contribution of physical health, mental health, general health, and total health care expenditures to patient satisfaction using a longitudinal, nationally representative sample.</p>
                </sec>
                <sec sec-type="methods">
                    <title>Methods</title>
                    <p>Using data from the 2010-2011 Medical Expenditure Panel Survey, analyses were conducted to predict patient satisfaction from patient-reported outcomes and total health care expenditures. The study sample consisted of adult participants (N=10,157), with sampling weights representative of 233.26 million people in the United States.</p>
                </sec>
                <sec sec-type="results">
                    <title>Results</title>
                    <p>The results indicated that patient-reported outcomes and total health care expenditure were associated with patient satisfaction such that higher physical and mental function, higher general health status, and higher total health care expenditure were associated with higher patient satisfaction.</p>
                </sec>
                <sec sec-type="conclusions">
                    <title>Conclusions</title>
                    <p>We found that patient-reported outcomes and total health care expenditure had a significant relationship with patient satisfaction. As more emphasis is placed on health care value and quality, this area of research will become increasingly needed and critical questions should be asked about what we value in health care and whether we can find a balance between patient satisfaction, outcomes, and expenditures. Future research should apply big data analytics to investigate whether there is a differential effect of patient-reported outcomes and medical expenditures on patient satisfaction across different medical specialties.</p>
                </sec>
            </abstract>
            <kwd-group>
                <kwd>health care quality</kwd>
                <kwd>value</kwd>
                <kwd>expenditure</kwd>
                <kwd>cost</kwd>
                <kwd>medical outcomes</kwd>
                <kwd>patient satisfaction</kwd>
                <kwd>Medical Expenditure Panel Survey</kwd>
                <kwd>patient-reported outcomes</kwd>
                <kwd>Affordable Care Act</kwd>
                <kwd>big data analytics</kwd>
            </kwd-group>
        </article-meta>
    </front>
    <body>
        <sec sec-type="introduction">
            <title>Introduction</title>
            <p>Value-based health care has become a buzzword for health care reforms across the globe. In the United States, the Affordable Care Act has placed huge emphasis on health care value and quality [<xref ref-type="bibr" rid="ref1">1</xref>]. Although it has yet to be clearly defined, health care quality is often linked to patient satisfaction [<xref ref-type="bibr" rid="ref2">2</xref>-<xref ref-type="bibr" rid="ref4">4</xref>]. Beginning on October 1, 2012, the Center for Medicare &#38; Medicaid Services (CMS) has tied Medicare reimbursements with patient satisfaction, as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems (CAHPS) survey. The CAHPS survey measures the following 5 aspects of patient satisfaction or perception of health care experiences: (1) access to care, (2) provider communication, (3) coordination of care, (4) shared decision-making, and (5) the office staff. Additionally, it contains a global rating item on patient satisfaction. The results of the patient satisfaction survey are estimated to put a hospital at risk of US $500,000 to US $850,000 on average for Medicare reimbursement [<xref ref-type="bibr" rid="ref5">5</xref>]. The stakes are high with patient satisfaction, but how can we improve patient satisfaction and what are the predictors of patient satisfaction?</p>
            <p>One question is &#34;what constitutes value in health care?&#34; Porter posited that health care value is linked to patient-reported outcomes (PROs) and expenditures [<xref ref-type="bibr" rid="ref6">6</xref>]. PROs are patients&#8217; self-reported health status based on their perceptions of their health conditions. PROs, in addition to information from clinical assessments, have become a critical component of medical assessment by directly receiving information from the patient&#8217;s perspective [<xref ref-type="bibr" rid="ref7">7</xref>]. Some argue that understanding PROs is critical to understanding patient satisfaction [<xref ref-type="bibr" rid="ref8">8</xref>]. PRO instruments, such as SF-12 v2, can measure various outcomes including physical health, mental health, and general health.</p>
            <p>While PROs have become increasingly important in assessing health care value, the second part of the value equation is cost or expenditures in health care. Prior research has showed mixed findings between expenditures and patient satisfaction [<xref ref-type="bibr" rid="ref9">9</xref>-<xref ref-type="bibr" rid="ref12">12</xref>]. Fenton et al [<xref ref-type="bibr" rid="ref11">11</xref>] found that higher inpatient utilization, lower emergency department utilization, higher total medical expenditures, higher prescription drug expenditures, and fewer emergency visits are associated with higher patient satisfaction. However, a review of the literature found no consistent relationship and the majority of studies only found a small association between expenditures and satisfaction [<xref ref-type="bibr" rid="ref10">10</xref>].</p>
            <p>Research has suggested that a number of sociodemographic characteristics correlate with patient satisfaction, but there is not a strong consensus [<xref ref-type="bibr" rid="ref13">13</xref>]. Several studies demonstrated that older patients, patients with better functional status, and clearer communication from doctors are related to greater patient satisfaction [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref14">14</xref>-<xref ref-type="bibr" rid="ref16">16</xref>]. Rahmqvist and Bara [<xref ref-type="bibr" rid="ref17">17</xref>] also found that older patients were more satisfied than younger patients [<xref ref-type="bibr" rid="ref17">17</xref>], yet critiques suggested that the magnitude of age as a predictor of satisfaction is small [<xref ref-type="bibr" rid="ref18">18</xref>]. Additionally, greater patient satisfaction has been associated with lower levels of education and income [<xref ref-type="bibr" rid="ref17">17</xref>-<xref ref-type="bibr" rid="ref19">19</xref>]. However, Hall and Dornan [<xref ref-type="bibr" rid="ref18">18</xref>] found no relationship among income, ethnicity, sex, or family size with patient satisfaction.</p>
            <p>Although sociodemographics and other nonmodifiable characteristics may influence patient satisfaction, they are not very useful for implementing changes in health care. Modifiable characteristics such as patient outcomes and health care expenditures are more useful for attaining actionable changes and reform in health care, yet there is a shortage of research in this area. There is also a lack of longitudinal, national studies examining the relationship between PROs, medical expenditures, and patient satisfaction. This study aims to fill this gap by investigating this relationship using a longitudinal, nationally representative sample, adjusting for various sociodemographics and health-related characteristics.</p>
        </sec>
        <sec sec-type="methods">
            <title>Methods</title>
            <sec>
                <title>Study Design</title>
                <sec>
                    <title>Overview</title>
                    <p>Data from the longitudinal study of adult respondents to the 2010-2011 longitudinal panel Medical Expenditures Panel Survey (MEPS) [<xref ref-type="bibr" rid="ref20">20</xref>] served as a basis for the comprehensive assessment of health care value and health care quality in this study. The MEPS is a nationally representative survey, sponsored by the Agency for Healthcare Research and Quality, which measures access, use, and cost of health care services. The survey consists of 3 major components, namely, (1) the household, (2) the medical provider, and (3) insurance. The household component samples were drawn from the respondents to the National Health Interview Survey by the National Center for Health Statistics. This study utilized data from the household component and included respondents aged 18 years or older. A list of all the variables used in this study is shown in <xref ref-type="app" rid="app1">Multimedia Appendix 1</xref>, and <xref ref-type="app" rid="app2">Multimedia Appendix 2</xref> contains all of the covariates included in the analyses. Capitalizing on MEPS&#8217;s longitudinal panel survey design, we sought to predict patient satisfaction from PROs and total health care expenditures, controlling for demographics, prior health status, and clinical characteristics.</p>
                </sec>
                <sec>
                    <title>Medical Expenditures</title>
                    <p>The MEPS collects data on various categories of medical expenditures such as prescription drugs, emergency patient visits, and inpatient hospital stays. The variable total expenditure is an aggregate of medical expenditures in various categories. In this study, we used total health care expenditures (EXP) from Year 1 (2010) as an independent variable.</p>
                </sec>
                <sec>
                    <title>Patient-Reported Outcomes</title>
                    <p>The MEPS also contains PROs data. Specifically, it contains data from the SF-12v2, which measures patients&#8217; self-reported functional health status and well-being. The SF-12v2&#8217;s physical health component score (PCS), the mental health component score (MCS), and the general health perceptions (GH) score from Year 1 were also included as independent variables in this study. The PCS and MCS possible scores range from 0 (worst health) to 100 (best health). To put GH in the same direction as the PCS and MCS scoring, we reverse coded the original GH such that the possible scores range from 1 (worst health) to 5 (best health).</p>
                </sec>
                <sec>
                    <title>Patient Satisfaction</title>
                    <p>We used the CAHPS&#8217;s single-item global rating of satisfaction in Year 2 (2011) as a dependent variable. This global patient satisfaction item (SAT) reflects patients&#8217; rating of their health care from all physicians and health care providers in the last 12 months when the patients were taking the survey. It is not a recall of a certain visit at a specific time (eg, at 3 month or 5 months ago), rather it represents a patient's average experience of all health care encounters within the last 12 months. The possible scores range from 0 (worst health care possible) to 10 (best health care possible). The survey was administered using computer-assisted personal interviewing technology.</p>
                </sec>
                <sec>
                    <title>Covariates</title>
                    <p>Based on a literature review, we identified a list of potential confounders from the MEPS data to be the covariates and adjusted for them when investigating the contribution of PROs and total health care expenditure to patient satisfaction. The list of potential confounders is included in <xref ref-type="app" rid="app2">Multimedia Appendix 2</xref>, which contains patients&#8217; age, sex, education, race, ethnicity, income, insurance coverage, provider characteristics, prior health status, and different clinical conditions. The covariates selected for the regression analyses were confounders that showed significant associations with patient satisfaction.</p>
                </sec>
            </sec>
            <sec>
                <title>Data Analysis</title>
                <p>The MEPS utilized a multistage, probability clustering sample design that enabled comprehensive examination of the US population. The sampling weight, stratification, clustering, multiple stages of selection, and disproportionate sampling from the MEPS were taken into account in the analyses so that the findings reported represented the entire US population. Sampling weight took into account the differential probability of sample selection and adjusted for nonresponses and missing data. Descriptive statistics were conducted to examine SAT, PCS, MCS, GH scores, EXP, and different service categories of medical expenditures across clinical conditions. We also performed descriptive statistics on all potential confounders and flagged those that had significant associations with patient satisfaction to be included as covariates in subsequent regression analyses.</p>
                <p>To investigate the contribution of PCS, MCS, GH, and EXP on patient satisfaction, we conducted logistic regressions with adjustment of covariates and reported the odds ratio with associated 95% CI. We recoded the PROs, satisfaction, and expenditure variables into low/high SAT, PCS, MCS, GH, and EXP prior to running the logistic regressions. All statistical tests were two sided, were set at an alpha level of .05, and were conducted using SAS 9.3. Institutional review board (IRB) and/or ethics committee approval was not required as the MEPS data are freely available to the general public online.</p>
            </sec>
        </sec>
        <sec sec-type="results">
            <title>Results</title>
            <sec>
                <title>Demographics</title>
                <p>The entire study sample consisted of adult participants (N=10,157), which represented 233.26 million adults (aged &#8805; 18 years) in the United States. The mean age was 47 years (SE 0.28, range 18-85). Approximately 52% (121 million/233.26 million) were female and the majority were white (81%, 188 million/233.26 million) and black (12%, 27 million/233.26 million). About 15% (34 million/233.26 million) were Hispanic, approximately 34% (79 million/233.26 million) were unemployed, and nearly 12% (27 million/233.26 million) spoke non-English at home (<xref ref-type="table" rid="table1">Table 1</xref>).</p>
                <table-wrap position="float" id="table1">
                    <label>Table 1</label>
                    <caption>
                        <p>Demographics of the sample from MEPS (weighted N=233.26 million; unweighted N=10,157).</p>
                    </caption>
                    <table width="568" border="0" cellpadding="7" cellspacing="0" rules="groups" frame="hsides">
                        <col width="77" />
                        <col width="120" />
                        <col width="65" />
                        <col width="65" />
                        <col width="65" />
                        <col width="65" />
                        <thead>
                            <tr valign="top">
                                <td colspan="2">
                                    <break />
                                </td>
                                <td colspan="2">Weighted</td>
                                <td colspan="2">Unweighted</td>
                            </tr>
                            <tr valign="top">
                                <td colspan="2">Variable</td>
                                <td>n (millions)</td>
                                <td>%</td>
                                <td>n (millions)</td>
                                <td>%</td>
                            </tr>
                        </thead>
                        <tbody>
                            <tr valign="top">
                                <td>
                                    <bold>Sex</bold>
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Male</td>
                                <td>113</td>
                                <td>48.3</td>
                                <td>2385</td>
                                <td>72.3</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Female</td>
                                <td>121</td>
                                <td>51.7</td>
                                <td>916</td>
                                <td>27.7</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Race</bold>
                                </td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>White</td>
                                <td>188</td>
                                <td>80.7</td>
                                <td>7060</td>
                                <td>69.5</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Black</td>
                                <td>27</td>
                                <td>11.7</td>
                                <td>1992</td>
                                <td>19.6</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>American Indian/Alaskan native</td>
                                <td>2</td>
                                <td>0.7</td>
                                <td>84</td>
                                <td>0.8</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Asian</td>
                                <td>12</td>
                                <td>5.1</td>
                                <td>805</td>
                                <td>7.9</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Native Hawaiian/Pacific Islander</td>
                                <td>2</td>
                                <td>0.7</td>
                                <td>72</td>
                                <td>0.7</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Multiple races</td>
                                <td>3</td>
                                <td>1.1</td>
                                <td>144</td>
                                <td>1.4</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Ethnicity</bold>
                                </td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Hispanic</td>
                                <td>34</td>
                                <td>14.5</td>
                                <td>2475</td>
                                <td>24.4</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Black (not Hispanic or another race)</td>
                                <td>27</td>
                                <td>11.4</td>
                                <td>1950</td>
                                <td>19.2</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Asian (not Hispanic or another race)</td>
                                <td>12</td>
                                <td>5.0</td>
                                <td>794</td>
                                <td>7.8</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Other race (not Hispanic or another race)</td>
                                <td>161</td>
                                <td>69.1</td>
                                <td>4938</td>
                                <td>48.6</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Hispanic</bold>
                                </td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Hispanic</td>
                                <td>34</td>
                                <td>14.5</td>
                                <td>2475</td>
                                <td>24.4</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Not Hispanic</td>
                                <td>200</td>
                                <td>85.5</td>
                                <td>7682</td>
                                <td>75.6</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Employment status</bold>
                                </td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Employed</td>
                                <td>154</td>
                                <td>66.2</td>
                                <td>6465</td>
                                <td>63.9</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Not employed</td>
                                <td>79</td>
                                <td>33.8</td>
                                <td>3653</td>
                                <td>36.1</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Marital status</bold>
                                </td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Married</td>
                                <td>124</td>
                                <td>53.4</td>
                                <td>5172</td>
                                <td>50.9</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Widowed</td>
                                <td>15</td>
                                <td>6.3</td>
                                <td>612</td>
                                <td>6.0</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Divorced</td>
                                <td>26</td>
                                <td>11.3</td>
                                <td>1173</td>
                                <td>11.5</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Separated</td>
                                <td>5</td>
                                <td>2.3</td>
                                <td>312</td>
                                <td>3.1</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Never married</td>
                                <td>62</td>
                                <td>26.8</td>
                                <td>2888</td>
                                <td>28.4</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Currently smoke</bold>
                                </td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Yes</td>
                                <td>39</td>
                                <td>18.3</td>
                                <td>1732</td>
                                <td>18.5</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>No</td>
                                <td>176</td>
                                <td>81.7</td>
                                <td>7606</td>
                                <td>81.5</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Language spoken at home</bold>
                                </td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>English</td>
                                <td>205</td>
                                <td>88.3</td>
                                <td>8009</td>
                                <td>79.2</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Spanish</td>
                                <td>19</td>
                                <td>8.1</td>
                                <td>1555</td>
                                <td>15.4</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Another language</td>
                                <td>8</td>
                                <td>3.6</td>
                                <td>542</td>
                                <td>5.4</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Highest level of education</bold>
                                </td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>&#160;</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>High school or less with no degree</td>
                                <td>31</td>
                                <td>13.4</td>
                                <td>1986</td>
                                <td>20.0</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>High-school graduate or GED</td>
                                <td>69</td>
                                <td>29.9</td>
                                <td>3239</td>
                                <td>32.5</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Associates degree, beyond college, but no degree</td>
                                <td>62</td>
                                <td>26.9</td>
                                <td>2359</td>
                                <td>23.7</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Bachelor's degree</td>
                                <td>45</td>
                                <td>19.4</td>
                                <td>1596</td>
                                <td>16.0</td>
                            </tr>
                            <tr valign="top">
                                <td>&#160;</td>
                                <td>Master's, PhD, or professional degree</td>
                                <td>24</td>
                                <td>10.4</td>
                                <td>777</td>
                                <td>7.8</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <p>This nationally representative adult population had a number of health conditions. About 32% (74.97 million/233.09 million) had high blood pressure and 5% (12.31 million/233.11 million) had coronary heart disease. Approximately 4% (8.52 million/233.20 million) had previously experienced a stroke. Almost 30% (70.59 million/233.07 million) had high cholesterol and 24% (56.34 million/233.18 million) had arthritis. There were 10% (23.48 million/233.20 million) diagnosed with cancer.</p>
                <p>The sample population visited a variety of providers; however, most visited a general/family practice physician (71%, 60.69 million/86.00 million) and internal medicine physicians (20%, 17.10 million/86.00 million) within the last 12 months. About 68% (101.57 million/150.09 million) stated that their providers always showed respect for their treatment, whereas 3% (3.89 million/150.09 million) stated that their providers never showed respect. Almost 96% (161.35 million/168.25 million) indicated that their providers explained treatment options but 4% (6.90 million/168.25 million) did not. Approximately 67% (156.18 million/233.26 million) had private insurance, 18% (41.31 million/233.26 million) had public health insurance, whereas over 15% (35.77 million/233.26 million) were uninsured. A detailed breakdown of the number of responses for each variable is not provided here but can be obtained by contacting the authors.</p>
            </sec>
            <sec>
                <title>Medical Expenditures</title>
                <p>The 2010 annual total health care expenditure in the US was over US $1.11 trillion and the average total health care expenditure per adult was US $4752.39 (<xref ref-type="table" rid="table2">Table 2</xref>). The total medical expenditures for emergency visits, hospital stay, dental care, and prescription drugs were US $7.17 billion, US $41.21 billion, US $62.87 billion, and US $252.45 billion, respectively. The US medical expenditures, by major service categories, by disease conditions are displayed in <xref ref-type="table" rid="table2">Table 2</xref>. <xref ref-type="table" rid="table3">Table 3</xref> presents the descriptive statistics for medical expenditure, outcomes, and patient satisfaction.</p>
                <table-wrap position="float" id="table2">
                    <label>Table 2</label>
                    <caption>
                        <p>US medical expenditure by service area, by condition, per adult in 2010 (in US $).</p>
                    </caption>
                    <table width="593" border="0" cellpadding="7" cellspacing="0" rules="groups" frame="hsides">
                        <col width="76" />
                        <col width="85" />
                        <col width="65" />
                        <col width="75" />
                        <col width="60" />
                        <col width="60" />
                        <col width="70" />
                        <thead>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Median</td>
                                <td>Mean</td>
                                <td>SE</td>
                                <td>Minimum</td>
                                <td>Maximum</td>
                            </tr>
                        </thead>
                        <tbody>
                            <tr valign="top">
                                <td>
                                    <bold>Emergency visits</bold>
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>High blood pressure</td>
                                <td>0</td>
                                <td>38.19</td>
                                <td>3.92</td>
                                <td>0</td>
                                <td>3406</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Coronary heart disease</td>
                                <td>0</td>
                                <td>60.95</td>
                                <td>11.80</td>
                                <td>0</td>
                                <td>1576</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Angina</td>
                                <td>0</td>
                                <td>77.89</td>
                                <td>16.52</td>
                                <td>0</td>
                                <td>900</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Stroke</td>
                                <td>0</td>
                                <td>56.73</td>
                                <td>11.30</td>
                                <td>0</td>
                                <td>1092</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Emphysema</td>
                                <td>0</td>
                                <td>60.23</td>
                                <td>14.10</td>
                                <td>0</td>
                                <td>701</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>High cholesterol</td>
                                <td>0</td>
                                <td>36.29</td>
                                <td>4.89</td>
                                <td>0</td>
                                <td>4570</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Cancer</td>
                                <td>0</td>
                                <td>34.52</td>
                                <td>5.72</td>
                                <td>0</td>
                                <td>936</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Arthritis</td>
                                <td>0</td>
                                <td>42.72</td>
                                <td>5.41</td>
                                <td>0</td>
                                <td>4570</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Asthma</td>
                                <td>0</td>
                                <td>48.23</td>
                                <td>9.12</td>
                                <td>0</td>
                                <td>4570</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Hysterectomy</td>
                                <td>0</td>
                                <td>52.49</td>
                                <td>9.38</td>
                                <td>0</td>
                                <td>5424</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Heart attack</td>
                                <td>0</td>
                                <td>56.23</td>
                                <td>11.52</td>
                                <td>0</td>
                                <td>732</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Hospital stay</bold>
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>High blood pressure</td>
                                <td>0</td>
                                <td>233.94</td>
                                <td>29.24</td>
                                <td>0</td>
                                <td>28,798</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Coronary heart disease</td>
                                <td>0</td>
                                <td>498.17</td>
                                <td>115.31</td>
                                <td>0</td>
                                <td>17,792</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Angina</td>
                                <td>0</td>
                                <td>674.49</td>
                                <td>190.66</td>
                                <td>0</td>
                                <td>17,792</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Stroke</td>
                                <td>0</td>
                                <td>480.89</td>
                                <td>123.35</td>
                                <td>0</td>
                                <td>17,792</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Emphysema</td>
                                <td>0</td>
                                <td>381.02</td>
                                <td>96.18</td>
                                <td>0</td>
                                <td>5155</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>High cholesterol</td>
                                <td>0</td>
                                <td>228.66</td>
                                <td>27.37</td>
                                <td>0</td>
                                <td>17,792</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Cancer</td>
                                <td>0</td>
                                <td>229.43</td>
                                <td>41.66</td>
                                <td>0</td>
                                <td>8923</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Arthritis</td>
                                <td>0</td>
                                <td>227.38</td>
                                <td>27.28</td>
                                <td>0</td>
                                <td>17,792</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Asthma</td>
                                <td>0</td>
                                <td>183.19</td>
                                <td>33.72</td>
                                <td>0</td>
                                <td>9289</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Hysterectomy</td>
                                <td>0</td>
                                <td>214.13</td>
                                <td>25.81</td>
                                <td>0</td>
                                <td>7550</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Heart attack</td>
                                <td>0</td>
                                <td>572.91</td>
                                <td>178.98</td>
                                <td>0</td>
                                <td>17,792</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Dental care</bold>
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>High blood pressure</td>
                                <td>0</td>
                                <td>235.39</td>
                                <td>20.11</td>
                                <td>0</td>
                                <td>15,692</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Coronary heart disease</td>
                                <td>0</td>
                                <td>252.75</td>
                                <td>68.19</td>
                                <td>0</td>
                                <td>10,289</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Angina</td>
                                <td>0</td>
                                <td>198.33</td>
                                <td>57.69</td>
                                <td>0</td>
                                <td>3514</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Stroke</td>
                                <td>0</td>
                                <td>180.72</td>
                                <td>38.08</td>
                                <td>0</td>
                                <td>3514</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Emphysema</td>
                                <td>0</td>
                                <td>250.03</td>
                                <td>75.47</td>
                                <td>0</td>
                                <td>5998</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>High cholesterol</td>
                                <td>0</td>
                                <td>273.77</td>
                                <td>22.51</td>
                                <td>0</td>
                                <td>15,692</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Cancer</td>
                                <td>0</td>
                                <td>291.01</td>
                                <td>31.46</td>
                                <td>0</td>
                                <td>6192</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Arthritis</td>
                                <td>0</td>
                                <td>259.89</td>
                                <td>21.74</td>
                                <td>0</td>
                                <td>15,692</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Asthma</td>
                                <td>0</td>
                                <td>203.07</td>
                                <td>23.56</td>
                                <td>0</td>
                                <td>5998</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Hysterectomy</td>
                                <td>0</td>
                                <td>266.83</td>
                                <td>23.91</td>
                                <td>0</td>
                                <td>9674</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Heart attack</td>
                                <td>0</td>
                                <td>188.15</td>
                                <td>58.59</td>
                                <td>0</td>
                                <td>5998</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <bold>Prescription drugs</bold>
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>High blood pressure</td>
                                <td>711.50</td>
                                <td>1934.43</td>
                                <td>82.76</td>
                                <td>0</td>
                                <td>50,667</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Coronary heart disease</td>
                                <td>2030.00</td>
                                <td>3209.79</td>
                                <td>246.04</td>
                                <td>0</td>
                                <td>23,355</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Angina</td>
                                <td>2080.50</td>
                                <td>3269.23</td>
                                <td>329.06</td>
                                <td>0</td>
                                <td>17,576</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Stroke</td>
                                <td>1459.00</td>
                                <td>2902.59</td>
                                <td>326.25</td>
                                <td>0</td>
                                <td>40,940</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Emphysema</td>
                                <td>2150.00</td>
                                <td>3292.43</td>
                                <td>334.82</td>
                                <td>0</td>
                                <td>15,071</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>High cholesterol</td>
                                <td>779.00</td>
                                <td>1985.17</td>
                                <td>85.30</td>
                                <td>0</td>
                                <td>40,940</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Cancer</td>
                                <td>691.00</td>
                                <td>2153.63</td>
                                <td>180.58</td>
                                <td>0</td>
                                <td>37,509</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Arthritis</td>
                                <td>914.50</td>
                                <td>2178.59</td>
                                <td>100.20</td>
                                <td>0</td>
                                <td>50,667</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Asthma</td>
                                <td>571.50</td>
                                <td>1863.06</td>
                                <td>130.80</td>
                                <td>0</td>
                                <td>31,763</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Hysterectomy</td>
                                <td>826.50</td>
                                <td>1826.24</td>
                                <td>104.19</td>
                                <td>0</td>
                                <td>40,940</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Heart attack</td>
                                <td>1858.00</td>
                                <td>3141.72</td>
                                <td>326.99</td>
                                <td>0</td>
                                <td>23,355</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
                <table-wrap position="float" id="table3">
                    <label>Table 3</label>
                    <caption>
                        <p>Descriptive statistics for medical expenditure, outcomes, and patient satisfaction.</p>
                    </caption>
                    <table width="518" border="0" cellpadding="7" cellspacing="0" rules="groups" frame="hsides">
                        <col width="220" />
                        <col width="137" />
                        <col width="118" />
                        <thead>
                            <tr valign="top">
                                <td>Variables</td>
                                <td>Mean (SE)</td>
                                <td>95% CI</td>
                            </tr>
                        </thead>
                        <tbody>
                            <tr valign="top">
                                <td>Physical health component score (PCS)</td>
                                <td>49.28 (0.16)</td>
                                <td>48.97-49.59</td>
                            </tr>
                            <tr valign="top">
                                <td>Mental health component score (MCS)</td>
                                <td>50.98 (0.14)</td>
                                <td>50.7-51.25</td>
                            </tr>
                            <tr valign="top">
                                <td>General health (GH)</td>
                                <td>3.55 (0.02)</td>
                                <td>3.52-3.58</td>
                            </tr>
                            <tr valign="top">
                                <td>Total health care expenditure (EXP), US $</td>
                                <td>4752.39 (145.43)</td>
                                <td>4465.61-5039.17</td>
                            </tr>
                            <tr valign="top">
                                <td>Patient satisfaction (SAT)</td>
                                <td>8.30 (0.03)</td>
                                <td>8.24-8.36</td>
                            </tr>
                        </tbody>
                    </table>
                </table-wrap>
            </sec>
            <sec>
                <title>Patient-Reported Outcomes</title>
                <p>The mean score for PCS, MCS, and GH was 49.28 (SE 0.16), 50.98 (SE 0.14), and 3.55 (SE 0.02), respectively. These scores were significantly correlated with each other (PCS with MCS, &#961;=.16, <italic>P</italic>&#60;.001; PCS with GH, &#961;=.96, <italic>P</italic>&#60;.001; MCS with GH, &#961;=.62, <italic>P</italic>&#60;.001).</p>
            </sec>
            <sec>
                <title>Patient Satisfaction</title>
                <p>As measured by CAHPS&#8217;s global rating, the mean patient satisfaction score across the national adult sample was 8.30 (SE 0.03). The following were some of the variables that were significantly associated with patient satisfaction: age (&#961;=.25, <italic>P</italic>&#60;.001), currently smoking (&#967;<sup>2</sup>
                    <sub>1</sub>=29.7, <italic>P</italic>&#60;.001), provider showed respect for treatment (&#967;<sup>2</sup>
                    <sub>3</sub>=75.5, <italic>P</italic>&#60;.001), and provider explained option to person (&#967;<sup>2</sup>
                    <sub>1</sub>=21.0, <italic>P</italic>&#60;.001). The complete list of all of the variables that were found to be associated with patient satisfaction is provided in <xref ref-type="app" rid="app2">Multimedia Appendix 2</xref>.</p>
            </sec>
            <sec>
                <title>Patient-Reported Outcomes, Medical Expenditures, and Patient Satisfaction</title>
                <p>Total health care expenditure was negatively related to PROs; individuals who had lower physical function (&#961;=&#8722;.43, <italic>P</italic>&#60;.001), lower mental function (&#961;=&#8722;.11, <italic>P</italic>&#60;.001), and lower general health (&#961;=&#8722;.51, <italic>P</italic>&#60;.001) had higher total health care expenditures. After adjusting for covariates, we found that PROs and total health care expenditure were highly related to patient satisfaction (<xref ref-type="table" rid="table4">Table 4</xref>). Higher physical function, higher mental function, higher general health status, and higher total health care expenditure were associated with higher patient satisfaction. The odds of those who had high GH being satisfied were 6 times greater than those who had low GH (adjusted OR 5.98, 95% CI 2.95-12.12). High GH was defined as those who had excellent GH and low GH was defined as those who had poor or fair GH. There was more than a 2-fold difference in patient satisfaction between those who had high and low PCS (adjusted OR 2.54, 95% CI 1.36-4.72) and a 2-fold difference between those who had high and low MCS (adjusted OR 1.95, 95% CI 1.20-3.15). Those who had high EXP being satisfied were 3 times greater than those who had low EXP (adjusted OR 3.20, 95% CI 1.47-6.98). High PCS, MCS, and EXP were defined by those respondents who had &#8805;75 percentile of the scores, whereas low PCS, MCS, and EXP were defined by those with &#60;25 percentile scores.</p>
                <table-wrap position="float" id="table4">
                    <label>Table 4</label>
                    <caption>
                        <p>Prediction of patient satisfaction.</p>
                    </caption>
                    <table width="518" border="0" cellpadding="7" cellspacing="0" rules="groups" frame="hsides">
                        <col width="162" />
                        <col width="63" />
                        <col width="147" />
                        <col width="90" />
                        <thead>
                            <tr valign="bottom">
                                <td>Independent variables</td>
                                <td>n</td>
                                <td>Adjusted odds ratio<sup>a</sup>
                                </td>
                                <td>95% CI</td>
                            </tr>
                        </thead>
                        <tbody>
                            <tr valign="top">
                                <td>Physical health component score (PCS)</td>
                                <td>4782</td>
                                <td>2.54</td>
                                <td>1.36-4.72</td>
                            </tr>
                            <tr valign="top">
                                <td>Mental health component score (MCS)</td>
                                <td>4728</td>
                                <td>1.95</td>
                                <td>1.20-3.15</td>
                            </tr>
                            <tr valign="top">
                                <td>General health (GH)</td>
                                <td>3251</td>
                                <td>5.98</td>
                                <td>2.95-12.12</td>
                            </tr>
                            <tr valign="top">
                                <td>Total health care expenditure (EXP)</td>
                                <td>5082</td>
                                <td>3.20</td>
                                <td>1.47-6.98</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <fn id="table4fn1">
                            <p>
                                <sup>a</sup>Covariates are listed in <xref ref-type="app" rid="app2">Multimedia Appendix 2</xref>.</p>
                        </fn>
                    </table-wrap-foot>
                </table-wrap>
            </sec>
        </sec>
        <sec sec-type="discussion">
            <title>Discussion</title>
            <sec>
                <title>Principal Findings</title>
                <p>The purpose of this study was to investigate the contribution of physical health, mental health, general health, and total health care expenditures to patient satisfaction. We found that higher scores of physical health, mental health, and general health were related to higher scores of patient satisfaction. Consistent with previous research, we found that some factors such as age and provider interactions could impact patient satisfaction. Additionally, total health care expenditure was associated with patient satisfaction. Taken together, findings from this study can help providers, payers, policy makers, and the general public better understand the relationship between PROs, health care expenditures, and satisfaction.</p>
                <p>General health demonstrated the strongest relationship with patient satisfaction. After accounting for demographics and various factors, we see that greater patient satisfaction is directly related to greater physical and mental health, although the relationship is stronger with physical health. The argument that the relation between higher patient satisfaction and better health is an artifact of the tendency of healthy patients to be satisfied is not new [<xref ref-type="bibr" rid="ref21">21</xref>]. This stresses the importance of controlling for prior health status as we did in this study and with the inclusion of prior clinical conditions into the model. Previous research found that a functional measure of health predicted greater satisfaction levels immediately following the medical treatment [<xref ref-type="bibr" rid="ref9">9</xref>]. Differing research results regarding the impact of patient satisfaction on health have been partially attributed to differences in how risk or health have been assessed as well as the time frame as to when the satisfaction scores were gathered [<xref ref-type="bibr" rid="ref22">22</xref>]. It may be that individuals who are in poor health have to visit a physician more often, increasing the likelihood of a bad or unsatisfactory visit. Prior experience with health care, along with age and mental status variables had been shown to impact patient expectations [<xref ref-type="bibr" rid="ref23">23</xref>]. Our study emphasizes the importance of controlling for prior health status, prior health care experience, nonmodifiable characteristics, and patient expectations when assessing the effect of patient satisfaction.</p>
                <p>Mental health often goes unnoticed or it is dismissed as someone having a bad day. Both identifying mental health issues and addressing problems require training that goes beyond that of a general physician. As a result, a patient or a provider often needs to raise a concern about mental health. A stigma still exists about discussing and treating mental health issues, which may lead patients to be less willing to discuss mental health conditions. Seeing a mental health specialist adds an additional cost for patients that they may want to avoid. Finally, patients might not even notice that they have mental health issues. These may be reasons why mental health is a weaker predictor of patient satisfaction than physical health.</p>
                <p>A surprising finding was that total health care expenditures also had a significant relation to patient satisfaction. In a recent review of health care quality, only one third of the 61 studies reviewed found a positive association between higher spending and better health care quality [<xref ref-type="bibr" rid="ref10">10</xref>], but did not address patient satisfaction directly as a measure of quality. While our findings add to the body of research that suggests an association between spending and patient satisfaction [<xref ref-type="bibr" rid="ref11">11</xref>], it contradicts other research that states there is no association [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref24">24</xref>]. It is possible that initiatives that improve PROs and control cost at the same time contribute to patient satisfaction. Instead of raising health care expenditures, health policy makers and providers should attend to modifiable characteristics that are within their control such as providers showing respect and providers explaining treatment options to enhance PROs and thus, patient satisfaction.</p>
            </sec>
            <sec>
                <title>Limitations</title>
                <p>We were limited by the measurement tools in the MEPS, thus limiting the data we could use to measure physical, mental, and general health. Newer instruments have been developed using advanced techniques and these instruments may have better psychometric properties than instruments included in MEPS. The MEPS was administered using computer-assisted personal interviewing technology and the results obtained from this mode of survey administration may be different from those obtained from other modes. Care needs to be taken when doing cross-comparisons of results from different modes in different studies. Furthermore, the definition of health care expenditures reflects the CMS&#8217;s definition but might not represent a complete assessment of medical expenditures. We were not able to look at diseases that were not included in MEPS. Even though we had adjusted for nonresponses and missing data in the sample, such adjustment could only be made to a certain degree. The adjustment might not be adequate in the event that nonrespondents differed from respondents. It is well-known that there could be a larger share of nonrespondents having severe illness, impairment, and dealing with poor social economic conditions on a daily basis. Additionally, the majority of the population is white, but within the past few years, the United States has seen a growth of racial and ethnic diversity. Therefore, our findings might not represent underrepresented minorities at this moment in time.</p>
                <p>Finally, the concept of patient satisfaction lacks a clear connotation and definition in the literature. It has sometimes been considered as a component of consumer marketing [<xref ref-type="bibr" rid="ref6">6</xref>] that measures important customer service qualities within the realm of health care. These qualities include effective provider communication, support from physicians, waiting time, fulfillment of patient requests, staff integrity, and shared decision making, and represent multiple dimensions of patient satisfaction. Together, these dimensions of patient satisfaction constitute a patient&#8217;s overall health care experience. It is this overall patient health care experience that this study used to define patient satisfaction. It is likely that we were not accounting for everything that comprises patient satisfaction. In the future it would be beneficial to collect different aspects of patient satisfaction data and examine them under a different lens.</p>
            </sec>
            <sec>
                <title>Future Research Directions</title>
                <p>Future research should consider other modifiable characteristics that may influence patient satisfaction so that changes can be enacted. Often, underrepresented minorities have different experiences with health care than European Americans. Therefore, investigating their perspectives may illuminate group differences. Finally, future research should apply business intelligence or big data analytics to investigate whether there is a differential effect of PROs and medical expenditures on patient satisfaction across different medical areas.</p>
            </sec>
            <sec>
                <title>Conclusions</title>
                <p>We found that PROs and total health care expenditure had a strong relationship with patient satisfaction. As more emphasis is placed on health care value and quality, this area of research will become increasingly needed. Critical questions should be asked about what we value in health care and whether we can find a balance between patient satisfaction, outcomes, and expenditures. These questions need to be asked to policy makers, physicians, patients, insurers, and the general public.</p>
            </sec>
        </sec>
    </body>
    <back>
        <app-group>
            <app id="app1">
                <title>Multimedia Appendix 1</title>
                <p>List of all MEPS variables examined in this study.</p>
                <media xlink:href="publichealth_v1i2e13_app1.pdf" xlink:title="PDF File (Adobe PDF File), 144KB" />
            </app>
            <app id="app2">
                <title>Multimedia Appendix 2</title>
                <p>Association between patient satisfaction and potential confounders. Variables are rank listed with the strongest relations to patient satisfaction at the top and the lowest relations at the bottom.</p>
                <media xlink:href="publichealth_v1i2e13_app2.pdf" xlink:title="PDF File (Adobe PDF File), 313KB" />
            </app>
        </app-group>
        <glossary>
            <title>Abbreviations</title>
            <def-list>
                <def-item>
                    <term id="abb1">CAHPS</term>
                    <def>
                        <p>Consumer Assessment of Healthcare Providers and Systems</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb2">CMS</term>
                    <def>
                        <p>Center for Medicare &#38; Medicaid Services</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb3">EXP</term>
                    <def>
                        <p>total health care expenditure</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb4">GH</term>
                    <def>
                        <p>general health</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb5">MCS</term>
                    <def>
                        <p>mental health component score</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb6">MEPS</term>
                    <def>
                        <p>Medical Expenditures Panel Survey</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb7">PCS</term>
                    <def>
                        <p>physical health component score</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb8">PRO</term>
                    <def>
                        <p>patient-reported outcomes</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb9">SAT</term>
                    <def>
                        <p>patient satisfaction</p>
                    </def>
                </def-item>
            </def-list>
        </glossary>
        <fn-group>
            <fn fn-type="conflict">
                <p>None declared.</p>
            </fn>
        </fn-group>
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</article>